
Medicinal mushrooms have been used for hundreds of years, mainly in Asian countries, to treat infections, pulmonary diseases, and cancer. In Japan and China, mushrooms have been approved as an adjunct to standard cancer treatments for over 30 years. Turkey tail, Reishi, Shiitake, and Maitake are some of the more common medicinal mushrooms. While research on the health benefits of mushrooms is limited, they are believed to have anti-inflammatory, antimicrobial, and immunomodulatory properties. However, the FDA has not approved the use of medicinal mushrooms for the treatment of cancer or any other medical condition.
| Characteristics | Values |
|---|---|
| Are mushrooms approved by the FDA for medicinal use? | No, the FDA has not approved the use of medicinal mushrooms as a treatment for cancer or any other medical condition. |
| Are mushrooms approved by the FDA for food use? | The FDA has not approved the use of the Amanita muscaria mushroom for food use. |
| Are mushrooms approved for use in cancer treatment in China and Japan? | Yes, medicinal mushrooms have been approved as an adjunct to standard cancer treatments in China and Japan for more than 30 years. |
| Are there any specific mushroom types approved for use in cancer treatment in China and Japan? | Turkey tail (Trametes versicolor or Coriolus versicolor), Reishi (Ganoderma lucidum), and Meshima (Phellinus linteus) are some mushrooms approved for use in cancer treatment in China and Japan. |
| Are there any specific mushroom supplements approved for use in cancer treatment? | Turkey tail mushroom supplements are approved in Japan as an immune-boosting supplement for individuals undergoing cancer treatment. |
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What You'll Learn
- Turkey tail mushrooms have been used to treat lung diseases in traditional Chinese medicine
- Reishi mushrooms are often used in cancer treatment protocols due to their immunomodulating and anti-inflammatory properties
- The FDA has not approved the use of medicinal mushrooms as treatment for cancer or any other medical condition
- Amanita muscaria mushrooms, also known as fly agaric, are not approved for food use due to safety concerns
- Medicinal mushrooms have been used to treat infections for hundreds of years, especially in Asian countries

Turkey tail mushrooms have been used to treat lung diseases in traditional Chinese medicine
Mushroom supplements are not approved by the U.S. Food and Drug Administration (FDA) for medicinal use. However, they are often used for wellness and to help manage stress. Turkey tail mushrooms (Trametes versicolor or Coriolus versicolor) have been used in traditional Chinese medicine for centuries to treat lung diseases and boost immunity. In traditional Chinese medicine, it is known as Yun Zhi, while in Japan, it is called Kawaratake (roof tile fungus). Its medicinal properties were first reported in the "Compendium of Materia Medica" and "Shen Non-Compendium Medica".
Turkey tail mushrooms have been used as a complementary treatment for cancer, especially in integrated cancer therapy in conjunction with chemotherapy or radiotherapy. They contain compounds known as polysaccharopeptide (PSP) and polysaccharide-K (PSK). PSK is an approved adjuvant cancer treatment in Japan. Polysaccharide K (PSK) is the best-known active compound in turkey tail mushrooms. Turkey tail mushrooms have been approved for clinical use in China since 1987 and in Japan since 1977.
Turkey tail mushrooms may help boost the immune system, which may be beneficial for people undergoing cancer treatment. A number of studies have shown that these mushrooms have immune-boosting properties. They also have antibacterial properties against several common pathogens. Previous laboratory studies have found that turkey tail extract may have antiviral properties against HIV, human papillomavirus, and herpes simplex virus. It may also have antifungal action against Candida albicans. However, studies differ on the strength of these effects, and not many have tested turkey tail extracts as solo treatments for these infections in humans.
Turkey tail mushrooms are generally safe, but they are a type of fungus, so anyone with a mushroom or mold allergy should avoid them. Taking any mushroom extract could cause a life-threatening reaction known as anaphylaxis. It is important to note that not all dietary supplement products are safe, and they should not be used as a replacement for medical treatment.
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Reishi mushrooms are often used in cancer treatment protocols due to their immunomodulating and anti-inflammatory properties
Reishi mushrooms, also known as Ganoderma lucidum, have been used in traditional Chinese medicine for centuries. They are believed to have various health benefits, including boosting immunity and energy levels, and are often used in cancer treatment protocols. While Reishi mushrooms are not a cure for cancer, they are thought to possess immunomodulating and anti-inflammatory properties that can support the body during cancer treatment.
Reishi mushrooms contain bioactive compounds, including triterpenoids and polysaccharides, that exhibit pharmacological activities such as antimicrobial, anti-inflammatory, immunomodulating, antioxidant, and antitumor effects. These compounds have been studied in laboratory and animal models, as well as in some human clinical trials. For example, a study in Japan involving 225 patients with benign colorectal tumors found that those who received an extract of G. lucidum mycelia (MAK) experienced a decrease in the number and size of tumors compared to those who did not receive MAK. Another study in China involving 36 patients with advanced lung cancer showed that an over-the-counter product made from Reishi, called Ganopoly, may help strengthen the immune system in patients undergoing chemotherapy or radiation therapy.
The anti-inflammatory properties of Reishi mushrooms are attributed to their triterpenes content, which inhibits the release of histamine and prevents allergic reactions and inflammations. Additionally, Reishi has been found to have immunomodulating effects, which can help regulate the immune system and enhance its ability to fight cancer. In traditional Chinese medicine, Reishi mushrooms are believed to prolong life, prevent aging, and increase energy.
While Reishi mushrooms have a long history of use in East Asian medicine, it is important to note that research on their efficacy in cancer treatment is still ongoing. Some studies suggest that Reishi mushrooms may provide a small benefit when combined with standard cancer treatments, such as chemotherapy and radiotherapy. However, randomized controlled trials have not supported the use of Reishi for all purposes, such as reducing cardiovascular risk factors associated with type 2 diabetes. More high-quality trials are needed to conclusively determine the effectiveness of Reishi mushrooms in cancer treatment.
In conclusion, Reishi mushrooms are often included in cancer treatment protocols due to their perceived immunomodulating and anti-inflammatory properties. While traditional medicine and some modern studies support their use, further research is required to fully understand their efficacy and safety in cancer treatment. As with any herbal supplement, it is important to consult a healthcare professional before use, as they can interact with certain medications.
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The FDA has not approved the use of medicinal mushrooms as treatment for cancer or any other medical condition
While medicinal mushrooms have been used for centuries in traditional medicine, particularly in Asian regions, they have not been approved by the U.S. Food and Drug Administration (FDA) for medicinal use. The FDA has issued warning letters to companies like Mushroom Revival, Inc. for making unapproved claims about the medicinal properties of their mushroom products.
Mushroom Revival, Inc. received a warning letter from the FDA on December 1, 2020, for its marketing of Cordyceps Militaris, Reishi, and Mush-10 products. The company claimed that these products had anti-inflammatory, antihistamine, and immune-boosting properties, with the ability to treat respiratory diseases, allergies, and even cancer. However, the FDA stated that these products are considered "new drugs" under the FD&C Act and require prior approval, which they had not received.
The FDA's role is to ensure the safety and efficacy of drugs before they are introduced to the market. In the case of Mushroom Revival, Inc., the FDA asserted that the company's mushroom products were not generally recognized as safe and effective for their intended uses. This is a critical step to protect consumers from potentially harmful products or false advertising.
While research on the medicinal properties of mushrooms is ongoing, and some compounds have shown promising results in vitro and in vivo, clinical studies on humans are still limited. These studies are necessary to assess the efficacy and safety of mushroom-based treatments within the complex human body system. Without sufficient clinical data and FDA approval, the public is prohibited from accessing these treatments under federal law.
It's important to note that some countries, like Australia, have approved the use of psychedelic-assisted therapy for patients with PTSD and treatment-resistant depression. Additionally, in China and Japan, certain mushroom-based drugs have been approved for clinical use, particularly in integrated cancer therapy. However, in the United States, the FDA has not yet approved the use of medicinal mushrooms as treatment for cancer or any other medical condition.
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Amanita muscaria mushrooms, also known as fly agaric, are not approved for food use due to safety concerns
Fly agaric is a large, white-gilled mushroom with a bright red cap covered in distinctive white warts. It is native to the temperate and boreal forests of the Northern Hemisphere but has now spread to the Southern Hemisphere as well. Its name is derived from its traditional use as an insecticide, as it contains compounds that attract and kill flies.
Despite its long history of cultural significance, fly agaric can cause poisoning, especially in children and those seeking its hallucinogenic effects. The psychoactive compounds muscimol, ibotenic acid, and muscarine are the main culprits, and while fatal poisonings are rare, they have been known to occur. As a result, the FDA has warned food manufacturers that Amanita muscaria and its compounds are not authorized for use in food due to safety concerns.
The market for psychoactive edibles containing fly agaric has grown substantially in recent years, with hundreds of brands sold online and in stores. The FDA's ruling does not prohibit people from growing or picking Amanita muscaria, but it does restrict its use as an ingredient in food products, citing the need to meet safety standards. The inaccurately labeling of food products containing this mushroom is a concerning issue that goes against federal regulations.
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Medicinal mushrooms have been used to treat infections for hundreds of years, especially in Asian countries
Reishi mushrooms have been traditionally used in Asian countries, particularly China and Japan, for their purported health benefits. They are believed to possess anti-inflammatory, antimicrobial, and anti-tumor properties, making them a popular choice for immunity support and cancer treatment. In Japan, reishi mushrooms are often used alongside chemotherapy and radiation therapy for cancer patients. Turkey tail (Trametes versicolor), another type of mushroom, has been used in traditional Chinese medicine to treat lung conditions and boost the immune system during cancer treatment.
The use of medicinal mushrooms is not limited to China and Japan; they have also been traditionally used in Korea, Vietnam, Thailand, India, and other Far Eastern civilizations. For example, Phellinus linteus, an endemic species in Korea, has been used for its medicinal properties. In Japan, the native shiitake mushroom (Lentinus edodes) has been a well-known medicinal mushroom since ancient times, with records dating back to 199 AD.
While medicinal mushrooms have a long history of use in Asian countries, their effectiveness as a treatment for various conditions is still being studied. There is growing interest in mycotherapy, and clinical trials are being conducted to expand our understanding of the safety and efficacy of mushroom supplements. However, it is important to note that the U.S. Food and Drug Administration (FDA) has not approved mushroom supplements for medicinal use.
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Frequently asked questions
No. The FDA has not approved the use of all mushrooms. For example, the Amanita muscaria mushroom, also known as fly agaric or fly amanita, is not approved for food use.
Turkey tail mushrooms, also known as Trametes versicolor or Coriolus versicolor, are approved in Japan as an immune-boosting supplement to individuals undergoing cancer treatment. In China, there are currently at least 12 C. versicolor-based drugs approved by the State Administration of Food and Drugs (SAFD) for clinical use.
Medicinal mushrooms are not approved by the U.S. Food and Drug Administration (FDA) for medicinal use. However, they are distributed as dietary supplements. In the United States, dietary supplements are regulated separately from foods, cosmetics, and drugs.

























