
Mushrooms, specifically psychedelic mushrooms, have been used for recreational, religious, and medicinal purposes. They contain the psychoactive ingredients psilocybin and psilocin, which affect the brain and body in various ways. While some people experience positive effects such as euphoria, sensory distortion, and increased emotional and brain plasticity, others may encounter negative consequences like hallucinations, anxiety, and panic. The impact of mushrooms on the brain remains a subject of ongoing research, with studies exploring both their potential therapeutic benefits and possible harmful long-term effects.
| Characteristics | Values |
|---|---|
| Hallucinogenic effects | Altered perception of time and space, intense changes in mood and feeling, sensory distortion, euphoria, hallucinations, agitation, psychosis, panic |
| Therapeutic effects | Rewiring the brain to ease depression, anxiety, PTSD, substance use disorders, and tobacco and alcohol use disorders |
| Physical side effects | Increase in blood pressure, heart rate, body temperature, tremors, numbness, weakness, uncoordinated movements, accidental self-harm |
| Long-term side effects | Change in personality, ability to recall memories, mental illness, long-lasting psychosis |
| Addiction | Non-addictive, low risk of addiction |
| Safety | Should be consumed in a supervised, medical setting |
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What You'll Learn
- Hallucinogenic mushrooms can cause dangerous behaviour and injuries
- Mushrooms can alter the chemical composition of brain cells
- Research suggests mushrooms can change a person's personality for a year or longer
- Mushrooms may cause memory issues, including false memories
- Mushrooms may trigger mental illness or long-lasting psychosis

Hallucinogenic mushrooms can cause dangerous behaviour and injuries
Hallucinogenic mushrooms, such as magic mushrooms, are mind-altering substances that can cause unpredictable and dangerous behaviour, which may lead to injuries. Magic mushrooms contain the psychoactive ingredients psilocybin and psilocin, which affect the brain and body in various ways. The effects of psilocybin are generally similar to those of LSD and include an altered perception of time and space, intense changes in mood and feeling, euphoria, hallucinations, and sensory distortion.
The quantity of the drug consumed, the user's past experiences, expectations, mental state, personality, and immediate environment may all affect their reaction to psilocybin. An altered sense of reality can lead to accidental self-harm, especially if the user is not in a safe environment. This is why the consumption of magic mushrooms should always happen in a supervised, medical setting.
The effects of psilocybin vary widely, and adverse side effects are often mild or moderate and may resolve with time. However, some people may experience disturbing hallucinations, anxiety, panic, agitation, or psychosis. These side effects can be distressing and harmful. Additionally, dried hallucinogenic mushrooms may contain other substances that affect their safety profile, and there is a risk of poisoning from picking the wrong types of mushrooms.
While the potential risks of hallucinogenic mushrooms are important to consider, recent research has also explored the therapeutic potential of psilocybin. Small clinical trials have shown that one or two doses of psilocybin, given in a therapeutic setting, can make dramatic and long-lasting changes in people suffering from depression, anxiety, and substance use disorders. Psilocybin may increase emotional and brain plasticity, and it has been shown to reduce negative affect and increase positive affect.
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Mushrooms can alter the chemical composition of brain cells
Magic mushrooms contain the psychoactive ingredients psilocybin and psilocin, which affect the brain and body in various ways. Psilocybin is a classic psychedelic compound that may have efficacy in treating mood and substance use disorders. It works by binding to and activating serotonin receptors in parts of the brain, such as the prefrontal cortex and amygdala. Serotonin is a key chemical in the brain that affects mood and perception.
Studies have shown that psilocybin can alter emotions and brain function for up to a month after a single high dose. One week after taking psilocybin, negative affect and amygdala response to facial affect stimuli were reduced, while positive affect and dorsal lateral prefrontal and medial orbitofrontal cortex responses to emotionally conflicting stimuli were increased. One month after taking psilocybin, negative affect and amygdala response returned to baseline levels, while positive affect remained elevated, and trait anxiety was reduced. These findings suggest that psilocybin may increase emotional and brain plasticity.
Psilocybin can also cause an altered perception of time and space, intense changes in mood and feeling, and sensory distortion. It may distort how some people who use the drug perceive objects and people in their environment. The effects of psilocybin vary widely between individuals, and factors such as the quantity of the drug consumed, past experiences, expectations, mental state, personality, and immediate environment may all affect an individual's response.
While magic mushrooms have a low risk of addiction, they can be harmful if they lead to distressing hallucinations, agitation, or psychosis. They can also cause physical side effects, such as increased blood pressure, heart rate, and body temperature. However, so far, no serious long-term side effects have been identified, and researchers are actively discovering ways that psilocybin can treat certain mental health conditions. Small clinical trials have shown that one or two doses of psilocybin, given in a therapeutic setting, can make dramatic and long-lasting changes in people suffering from depression, anxiety, and other mental health disorders.
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Research suggests mushrooms can change a person's personality for a year or longer
Mushrooms are hallucinogenic drugs that alter the chemical composition of brain cells, leading to profound shifts in perception and sensation. While concerns have been raised about their impact on heart function and the potential for long-lasting psychosis, recent studies suggest that mushrooms may offer therapeutic benefits when used in controlled settings.
Research has indicated that psilocybin, the active ingredient in "magic mushrooms," can induce lasting personality changes, particularly an increase in "openness." This trait is associated with a willingness to explore new ideas and experiences, enhanced creativity, and a greater appreciation for art and emotion. The effects of psilocybin on personality have been observed to persist for at least 12 months and, in some cases, may lead to permanent alterations.
The Johns Hopkins University School of Medicine researchers found that individuals who underwent mystical experiences while under the influence of psilocybin exhibited more significant personality changes. These experiences were characterised by feelings of profound connectedness, transcendence, joy, and peace. As a result, individuals became more open about their feelings and developed a different perspective on themselves and their surroundings.
The potential for psilocybin to facilitate enduring personality changes has sparked interest in its therapeutic applications. Small clinical trials have demonstrated that one or two doses of psilocybin, administered in a therapeutic setting, can produce dramatic and long-lasting improvements in individuals suffering from depression, anxiety, and substance use disorders. The reduction of clinical symptoms has been observed to last up to 128 months after 1 to 3 psilocybin administrations.
While the exact mechanisms behind these changes are not yet fully understood, the research suggests that psilocybin interacts with serotonin receptors in the brain, which play a crucial role in regulating mood and cognition. Further controlled studies are needed to expand our understanding of the long-term effects of psilocybin on brain function and personality.
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Mushrooms may cause memory issues, including false memories
While the use of psychedelic mushrooms has been associated with various mental health benefits, there are concerns about their impact on memory. Mushrooms with hallucinogenic properties, such as psilocybin mushrooms, can alter an individual's perception and sensation, leading to profound shifts in their experience. These shifts can result in memory issues, including the potential formation of false memories.
A study published in the British Journal of Psychiatry suggests that the persistent effects of mushrooms can impact an individual's ability to recall memories accurately. The study indicates that portions of the brain fire at different rates when influenced by mushrooms, which can lead to two main issues with memory. Firstly, individuals may remember events or details that never actually occurred, creating false memories. Secondly, they may embellish the few details they can recall, filling in gaps with fabricated information.
The implications of these memory distortions are unclear and potentially concerning, especially for individuals with traumatic past experiences they wish to forget. The impact of mushrooms on memory underscores the profound power of these substances and raises questions about their long-term effects on mental health. While some studies suggest that psilocybin mushrooms are non-addictive and can positively impact brain health, the potential for memory distortions highlights the importance of further research to fully understand the risks and benefits associated with their use.
It is worth noting that the effects of psilocybin mushrooms vary widely between individuals, and factors such as mental state, personality, and environment play a role in the intensity of the experience. Additionally, the quantity of mushrooms consumed can also influence the likelihood of adverse effects, with higher doses potentially increasing the risk of negative experiences. While the formation of false memories is a concern, it is important to recognize that psilocybin mushrooms have shown promise in treating various mental health conditions, including depression, anxiety, and substance use disorders.
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Mushrooms may trigger mental illness or long-lasting psychosis
While some sources claim that magic mushrooms have the potential to trigger mental illness or long-lasting psychosis, the evidence is mixed. Research suggests that psilocybin, the psychedelic compound found in magic mushrooms, can cause both positive and negative mental health effects. On the one hand, psilocybin has been shown to reduce negative moods, increase positive moods, and decrease amygdala reactivity to negative stimuli. This suggests that psilocybin may be an effective treatment for mood and substance use disorders, as well as conditions like depression, anxiety, and PTSD.
On the other hand, psilocybin can cause unpleasant side effects, including disturbing hallucinations, anxiety, panic, and, in rare cases, accidental self-harm. Additionally, psilocybin can alter the chemical composition of brain cells, affecting perception, sensation, and heart function. There is also a risk of unintentional fatal poisoning if the wrong type of mushroom is consumed.
While some studies suggest that psilocybin can change a person's personality for a year or longer, it is difficult to determine the long-term effects of psilocybin on mental health. Some research indicates that the positive effects of psilocybin can last for several months to years, while others suggest that the benefits may wane over time.
Overall, while magic mushrooms may have therapeutic potential for some mental health conditions, they should be consumed in a supervised, medical setting to minimize the risk of adverse events. More research is needed to fully understand the potential risks and benefits of psilocybin for brain health.
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Frequently asked questions
Hallucinogenic mushrooms can alter the chemical composition of brain cells and produce profound shifts in perception and sensation. However, there is ongoing research into the potential of psilocybin, the psychedelic compound found in mushrooms, to positively impact brain health and treat mental health conditions.
The risks of taking hallucinogenic mushrooms include unpredictable and potentially dangerous behaviour, physical side effects, and psychological distress in the form of extreme anxiety or short-term psychosis. In rare cases, an altered sense of reality can lead to accidental self-harm.
Small clinical trials have shown that one or two doses of psilocybin in a therapeutic setting can make dramatic and long-lasting positive changes in people suffering from mental health conditions such as depression, anxiety, and substance use disorders.
Research into the long-term side effects of hallucinogenic mushrooms is ongoing. While some studies have observed very few long-term side effects, it is not clear how these drugs might impact all people. There are concerns that they could trigger a mental illness or cause long-lasting psychosis.

























