
Mushrooms are a popular food worldwide, but they are also prone to microbiological spoilage, which can lead to the generation of biogenic amines (BAs). Tyramine is one such BA, and it can be dangerous for those with certain medical conditions or medication regimens. High levels of tyramine can cause migraine headaches and increase blood pressure, so it is important to understand how much of this compound is present in mushrooms.
| Characteristics | Values |
|---|---|
| Are mushrooms high in tyramine? | Mushrooms and mushroom products are very popular in many countries and can be a source of biogenic amines, including tyramine. However, most mushroom products do not contain these compounds in quantities that could threaten consumers' health and lives. |
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What You'll Learn

Mushrooms are a source of tyramine
Mushrooms, particularly those that are processed or unprocessed, contain tyramine. A study analysing the content of biogenic amines in mushrooms from the Polish market found that while spermidine was the most abundant biogenic amine, tyramine was also present. This study included both cultivated and wild-growing mushrooms, such as white and brown button mushrooms, oyster mushrooms, and shiitake mushrooms.
The presence of tyramine in mushrooms is important to note, especially for individuals who are sensitive to its effects. High levels of tyramine in the body can lead to increased blood pressure and other potential health concerns. Therefore, those who already have high blood pressure or are taking certain medications need to be cautious when consuming mushrooms or other foods with high tyramine levels.
It is worth mentioning that the same study from Poland concluded that most mushroom products did not contain biogenic amines in quantities that posed a significant threat to consumers' health. However, it is always advisable for individuals to be aware of their specific dietary needs and sensitivities. Overall, mushrooms are a source of tyramine, and while they may not cause harm to everyone, certain individuals may need to moderate their consumption or opt for alternative food choices.
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Tyramine is a natural compound
The Polish market offers a variety of fresh and cultivated mushrooms, such as white and brown button mushrooms, oyster mushrooms, and shiitake mushrooms, as well as processed mushroom products. A study analyzed the content of seven BAs, including tyramine, in 47 processed mushroom products and six unprocessed mushrooms purchased from Polish stores. Spermidine was found to be the most abundant BA, detected in most processed products and all raw material samples.
While the study did not find life-threatening levels of BAs in the mushroom products, significant differences in BA content were observed. Dried forest mushrooms, in particular, were noted to have higher levels of BAs. However, it is important to note that the effects of tyramine can vary depending on individual sensitivity and medication use.
High amounts of tyramine can lead to several health issues. The most common problem associated with tyramine is migraine headaches. Tyramine can trigger nerve cells to release norepinephrine, a hormone that increases blood pressure and heart rate. This can be particularly concerning for individuals already suffering from high blood pressure. Additionally, some medications can interfere with monoamine oxidase production, an enzyme responsible for breaking down tyramine, making the consumption of tyramine dangerous.
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High tyramine levels can cause migraines and high blood pressure
Tyramine is a natural compound found in plants and animals. It is a byproduct of tyrosine breakdown, an amino acid. While tyramine is commonly found in many foods, high levels of it in the body can cause several health issues. The two most common health issues associated with high tyramine levels are migraines and high blood pressure.
High tyramine levels can trigger nerve cells to release norepinephrine, a hormone that increases blood pressure and heart rate. People who already have high blood pressure need to be cautious when consuming foods with high levels of tyramine. The most common signs of a sudden increase in blood pressure are worth knowing if you are taking MAOIs (monoamine oxidase inhibitors). If you experience any of these symptoms after consuming high-tyramine foods, you may require medical attention.
Some foods that are high in tyramine include aged cheeses like cheddar, blue cheese, Swiss cheese, parmesan, feta, and Camembert. Citrus fruits like oranges, grapefruits, lemons, limes, and tangerines also contain high levels of tyramine. Tropical fruits tend to have higher tyramine levels when ripened, so ripe bananas, pineapples, and avocados should be avoided if you are sensitive to tyramine. Additionally, fermented alcohol contains significant amounts of tyramine, including beer, red wine, vermouth, sherry, and some liqueurs.
Mushrooms and mushroom products are popular worldwide and can be a source of biogenic amines, including tyramine. While most mushroom products do not contain enough tyramine to threaten consumers' health, some dried forest mushrooms may have higher levels. Spermidine, a type of biogenic amine, was found to be the most abundant in the mushroom samples tested.
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Tyramine content in mushrooms varies
Tyramine is a natural compound found in plants and animals. It is a byproduct of tyrosine breakdown, an amino acid. While tyrosine and tyramine are commonly found in many foods, high amounts of tyramine can cause several health issues such as migraine headaches and high blood pressure. Certain medications can also interfere with monoamine oxidase production, which breaks down tyramine, making its consumption dangerous.
Mushrooms and mushroom products are popular in many countries, but they can be a source of biogenic amines. The Polish market, for instance, offers fresh cultivated mushrooms, including white and brown button mushrooms, oyster, shiitake, and various processed products from both cultivated and wild-growing mushrooms. The content of seven biogenic amines, including tyramine, was analysed in 47 processed mushroom products and 6 unprocessed mushrooms purchased from Polish stores.
Spermidine was the most abundant biogenic amine detected in the mushroom samples. It was found in 41 out of 47 types of processed products and all raw material samples. The tyramine content in the unprocessed samples of white button mushrooms ranged from 1686.58 to 2714.74 mg kg–1. While significant differences in the content of biogenic amines were observed in mushroom products, most did not contain these compounds in quantities that posed a significant health risk.
Overall, while mushrooms do contain tyramine, the levels can vary depending on the type and processing of the mushroom. The tyramine content in mushrooms does not appear to be high enough to cause significant health concerns for most individuals. However, those sensitive to tyramine or taking certain medications may need to monitor their intake and consult with a healthcare professional if they experience any adverse effects.
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Tyramine is a biogenic amine
Mushrooms are a rich source of protein and are perishable. They are susceptible to microbiological spoilage due to the absence of a protective cuticle. This makes them prone to the generation of biogenic amines (BAs). Biogenic amines, including tyramine, are organic compounds produced by the breakdown of amino acids. Tyramine, in particular, is formed from the breakdown of tyrosine. While tyramine is naturally present in many foods, its consumption should be approached with caution by certain individuals.
Mushrooms available in the Polish market, for instance, have been analysed for their biogenic amine content. This includes both processed and unprocessed mushrooms, such as white and brown button mushrooms, oyster mushrooms, shiitake mushrooms, and wild-growing varieties. The analysis revealed that spermidine was the most prevalent biogenic amine in the mushroom samples, followed by tyramine. While the presence of tyramine in mushrooms is notable, it is important to understand its potential effects on human health.
Tyramine is known to trigger the release of norepinephrine, a hormone that increases blood pressure and heart rate. Consequently, individuals with high blood pressure are advised to exercise caution when consuming foods with significant tyramine levels. Additionally, certain medications, such as monoamine oxidase inhibitors (MAOIs), can interfere with the body's ability to process tyramine, making its consumption potentially dangerous. High levels of tyramine in the body can lead to adverse health effects, with the most common being migraine headaches.
It is worth noting that while mushrooms may contain tyramine, the levels are typically not high enough to pose a significant threat to consumer health. Nevertheless, for individuals sensitive to tyramine or those on specific medications, it is important to be mindful of tyramine content in mushrooms and other food sources. Overall, tyramine is a biogenic amine that can have important implications for certain individuals, and its presence in mushrooms, although generally safe, underscores the need for awareness and moderation in consumption.
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Frequently asked questions
Mushrooms and mushroom products are very popular in many countries around the world, and they can be a source of biogenic amines, including tyramine. However, most mushroom products have not been shown to contain these compounds in a quantity that could threaten consumer health and life.
Tyramine can trigger nerve cells to release norepinephrine, a hormone that increases blood pressure and heart rate. High levels of tyramine in the body can cause high blood pressure and migraine headaches. People who are sensitive to tyramine, do not produce enough of the monoamine oxidase enzyme to process it, or are taking certain medications should be careful when consuming foods with high tyramine levels.
Many foods are high in tyramine, including aged cheeses such as cheddar, blue, Swiss, parmesan, feta, and Camembert. Citrus fruits like oranges, grapefruits, lemons, limes, and tangerines also contain high levels of tyramine, as do some fermented alcoholic beverages such as beer, red wine, vermouth, and sherry.

























