
Mushrooms are part of the fungal kingdom and play an important role in our ecosystem. They are responsible for breaking down waste and recycling usable nutrients back into the soil, enabling plants to survive. Interestingly, mushrooms share more DNA with humans than with plants. In fact, humans and fungi share nearly 50% of their DNA. Recent studies have discovered that paternal and maternal DNA in mushrooms are expressed at different times during development, with genes from both parents being active at different times in the process. This new understanding of mushroom DNA can help breed new strains and improve the cultivation of edible mushrooms.
| Characteristics | Values |
|---|---|
| DNA structure | Mushrooms contain DNA and are part of the fungal kingdom |
| Similarity to humans | Humans share nearly 50% of their DNA with mushrooms |
| Similarity to plants | Mushrooms are more closely related to humans than to plants |
| Paternal and maternal DNA | Paternal and maternal DNA in mushrooms are active at different times |
| Alternative splicing | Occurs in mushrooms, which can lead to mutations |
| Vitamin D production | Mushrooms produce vitamin D when exposed to sunlight, like humans |
| Carbohydrate storage | Mushrooms store carbohydrates as glycogen, like humans |
| Cell wall composition | Mushrooms use chitin to build cell walls, like insects |
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What You'll Learn

Mushrooms and humans share nearly 50% of their DNA
Mushrooms, which are a type of fungus, share nearly 50% of their DNA with humans. This means that mushrooms are more closely related to humans than they are to plants. While mushrooms were once considered plants, they now fall under their own kingdom, Fungi.
Genetic comparisons have revealed that fungi and animals share genetic characteristics that plants do not have. For instance, fungi and animals share a common ancestor, whereas plants constitute an independent evolutionary lineage. This means that mushrooms are more similar to humans and animals than they are to plants. In fact, the DNA in fungi more closely resembles the DNA of animals. Only a few tiny changes in our DNA structure differentiate us from fungi, giving us our variations in eye, skin, and hair colour.
The discovery that humans and mushrooms share a significant amount of DNA has important implications for medicine. For example, fungi have developed immunities against some viruses that affect humans and animals. By studying these natural immunities, we may be able to extract and use them to strengthen our defences against these viruses. Additionally, mushrooms have been found to have various health benefits, and some experts believe that they can be used as a form of medicine to treat mental health conditions such as anxiety, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and depression.
Furthermore, understanding the molecular mechanisms of mushroom DNA can help breed new strains that improve the cultivation of edible mushrooms. Recent research has also revealed that paternal and maternal DNA in fungi are active at different times during mushroom development. This discovery has important implications for understanding gene expression in mushrooms and could lead to new insights into mushroom formation.
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Mushrooms are part of the Kingdom Fungi
Mushrooms are indeed part of the Kingdom Fungi. The word "fungus" is derived from the Latin "fungus" (mushroom), which was used in the writings of Horace and Pliny. The English word is directly adopted from this Latin term, which in turn comes from the Greek word "sphongos" ("sponge"), referring to the macroscopic structures and morphology of mushrooms and molds.
The Kingdom Fungi is composed of seven phyla: Basidiomycota, Ascomycota, Glomeromycota, Neocallimastigomycota, Blastocladiomycota, Chytridiomycota, and Microsporidia. The 2007 classification of Kingdom Fungi was the result of collaborative research involving dozens of mycologists and other scientists working on fungal taxonomy. This classification recognizes seven phyla, two of which—Ascomycota and Basidiomycota—are contained within the subkingdom Dikarya, the most species-rich and familiar group, including all the mushrooms, most food spoilage molds, and most plant-pathogenic fungi.
Fungi, including mushrooms, are more closely related to animals than to plants. They share genetic characteristics with animals that plants do not have. Humans and mushrooms are nearly 50% alike in terms of DNA, with only a few tiny changes in DNA structure setting them apart. Fungi are some of the most widely distributed organisms on Earth and are of great environmental and medical importance. They are the primary degraders of organic matter in the environment, turning dead plants into small nutrient building blocks that other organisms can use.
Recent studies have investigated the replacement of animal meat with mushrooms in the formulation of sausages. Mushrooms are poor in fat and digestible carbohydrates, are rich in fiber and protein, have a well-balanced composition of minerals and vitamins, and are low in calories.
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Fungi and animals share genetic characteristics that plants don't
Mushrooms, a type of fungus, share more DNA with humans than with plants. Fungi and animals share genetic characteristics that plants do not have. This has been confirmed by various experts, including mycologist and author Paul Stamets, who asserted that humans share almost 50% of their DNA with fungi. Matt Kasson, an associate professor of mycology at West Virginia University, and John Walker, a professor at Appalachian State University who studies fungi, concur with this assertion.
The first hypotheses about the relationship between fungi and animals emerged in the 1950s, and scientists have since tested and confirmed these suspicions. One notable difference between fungi and plants is that some fungi can move or appear to crawl, whereas no plant possesses this motility. This movement is achieved through flagella, a tail that whips like a sperm cell. Additionally, fungi have rigid cell walls that support them, distinguishing them from both plants and animals.
Fungi, including mushrooms, are more closely related to animals than to plants. This relationship can be traced back to a common ancestor shared by fungi and animals, forming a clade called opisthokonta. The name opisthokonta refers to the presence of a single, posterior flagellum in their last common ancestor. This classification is based on molecular evidence and computational phylogenetics comparing eukaryotes, providing strong support for the separation of fungi and plants.
Furthermore, fungi exhibit unique genetic characteristics not found in plants. For instance, many fungi possess two different nuclei in their cells, each containing distinct genetic material. In contrast, humans have a single nucleus where DNA from both parents is mixed. Recent research has revealed that genes from parental DNAs in fungi are expressed at different times during mushroom development, a phenomenon not previously observed. This discovery has significant implications for breeding new strains of edible mushrooms and improving their cultivation.
While the genetic relationship between fungi and animals is intriguing, it is important to note that the meaty taste of mushrooms may not be solely attributed to this shared ancestry. According to Walker, the taste is likely due to the presence of glutamate, a neurotransmitter found in various savory foods, including meats. However, the absence of genetic research makes it challenging to establish a definitive link between the mushroom's genetic relationship and its taste.
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Mushrooms inherit DNA from both parents
Mushrooms, a type of fungus, share more DNA with humans than with plants. They are more closely related to animals than plants, exhibiting genetic characteristics that are absent in plants.
Thies Gehrmann, a TU Delft doctoral candidate, investigated gene expression in both a model mushroom and the common edible mushroom. Gehrmann's research revealed that genes on both parental DNAs are expressed at different times during the mushroom's development, a phenomenon previously unknown. This finding is significant because it means that when studying genes involved in mushroom formation, researchers must first determine whether the paternal or maternal nucleus is active.
Furthermore, Gehrmann's work also shed light on alternative splicing in fungi, a process where a single gene can produce different proteins, each with its own function. Abnormal alternative splicing has been linked to cancer, autism, and serious developmental disorders in mammals. However, despite these consequences, there has been limited research into alternative splicing in fungi. Gehrmann's research addressed this gap by demonstrating thousands of cases of alternative splicing in the fungus S. commune.
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Mushrooms produce vitamin D when exposed to sunlight, like humans
Mushrooms are a member of the Fungi kingdom and share similar genetic characteristics with animals, including humans. In fact, according to mycologist and author Paul Stamets, humans share nearly 50% of their DNA with fungi.
Like humans, mushrooms can produce vitamin D when exposed to sunlight. Mushrooms exposed to sunlight or UV radiation are an excellent source of dietary vitamin D2. This is because they contain high concentrations of the vitamin D precursor, provitamin D2. Provitamin D2 absorbs UV radiation between 240 and 320 nm and acts as a sunscreen. When exposed to UVB radiation, provitamin D2 is converted to previtamin D2, which then rapidly isomerizes to vitamin D2 in a similar manner to the process in human skin.
Vitamin D is an essential vitamin that plays a vital role in human metabolism and immune function. Exposing mushrooms to sunlight is a natural way to increase their vitamin D content. The vitamin D levels in shiitake mushrooms dried with their gills facing upwards for six hours a day over two days soared from 100 IU/100 grams to nearly 46,000 IU/100 grams.
However, it is important to note that the process of vitamin D synthesis in mushrooms requires specific conditions, including the right intensity and duration of UV exposure. Sunlight intensity and UVB radiation levels vary depending on factors such as time of day, season, geographical location, and weather conditions. Commercial producers of mushrooms utilize controlled environments and artificial UV light to enhance vitamin D synthesis.
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Frequently asked questions
Yes, mushrooms have DNA.
Mushrooms are more closely related to humans than plants. Fungi, including mushrooms, share genetic characteristics with animals that they do not share with plants.
Humans share about 50% of their DNA with fungi.
Mushrooms inherit DNA from both parents, but this is not mixed in a single nucleus as in humans. Genes from the parental DNAs are expressed at different times in mushroom development.

























