
Mushrooms are more closely related to humans than to plants, sharing nearly 50% of their DNA with humans. Genetic studies have shown that animals and fungi share a common ancestor, branching away from plants around 1.1 billion years ago. Fungi, including mushrooms, share genetic characteristics with animals that are not present in plants. Mushrooms and humans have several similarities, such as the production of vitamin D when exposed to sunlight and the storage of carbohydrate energy as glycogen.
| Characteristics | Values |
|---|---|
| Similarity in DNA | Humans share nearly 50% of their DNA with mushrooms |
| Carbohydrate energy storage | Mushrooms and humans store it as glycogen, while plants use starch |
| Cell wall composition | Fungi and insects use chitin, while plants use cellulose |
| Vitamin D production | Mushrooms and humans produce vitamin D when exposed to sunlight |
| Common ancestor | Animals and fungi share a common ancestor, branching away from plants around 1.1 billion years ago |
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What You'll Learn

Humans and mushrooms share nearly 50% of their DNA
Mushrooms and humans share nearly 50% of their DNA, according to mycologist and author Paul Stamets. This is because fungi, including mushrooms, are more closely related to animals than plants, with both sharing a common ancestor that branched off from plants around 1.1 billion years ago. This common ancestor was likely a single-celled organism with sperm-like characteristics that later developed a stronger cell wall.
Genetic studies have found similarities in certain proteins in animals and fungi that are not present in plants or bacteria. For example, both mushrooms and humans store carbohydrate energy as glycogen, while plants use starch. Fungi and insects use chitin to build cell walls, while plants use cellulose. Furthermore, mushrooms, like humans, produce vitamin D when exposed to sunlight.
The close genetic relationship between mushrooms and humans may explain why mushrooms taste meaty, although this has not been proven. The shared ancestry between mushrooms and animals could also explain why mushrooms possess medicinal properties that are beneficial to humans. For instance, mushrooms have been used to treat diseases such as tuberculosis and cancer, and they may even help save the endangered honeybee population by strengthening their immunity against viruses carried by mites.
The fact that mushrooms share nearly 50% of their DNA with humans highlights the importance of fungi in the natural world and their potential for medicinal use.
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Mushrooms and humans both produce vitamin D when exposed to sunlight
Mushrooms and humans share a surprising number of similarities. Recent research has shown that mushrooms are more closely related to humans than to plants. Genetic studies have revealed that animals and fungi share a common ancestor, branching away from plants around 1.1 billion years ago. This common ancestor was likely a single-celled organism with sperm-like characteristics that later developed a stronger cell wall.
One intriguing parallel between mushrooms and humans is their ability to produce vitamin D when exposed to sunlight. This shared trait further underscores the close genetic relationship between the two. Indeed, it has been suggested that humans share nearly 50% of their DNA with fungi, an astonishing figure that highlights the complex evolutionary history we share with these organisms.
The process of vitamin D production in mushrooms is similar to that in humans. When exposed to sunlight, a precursor molecule in the mushroom's cells, ergosterol, undergoes a chemical transformation and converts into vitamin D2, a form of vitamin D. Similarly, in humans, a precursor molecule in the skin, 7-dehydrocholesterol, absorbs UVB radiation from sunlight and converts into vitamin D3, another form of vitamin D.
This ability to produce vitamin D is not only a fascinating biological quirk but also has implications for the nutritional value of mushrooms. Mushrooms are a popular ingredient in many dishes, and their meat-like taste and texture have contributed to their culinary appeal. By exposing mushrooms to sunlight before consumption, one can increase their vitamin D content, thereby enhancing their nutritional benefits.
The discovery of shared traits between mushrooms and humans highlights the intricate connections within the natural world. It invites further exploration of the potential benefits that mushrooms may offer in various fields, from medicine to environmental sustainability. As researchers continue to uncover the secrets of this ancient bond, we gain a deeper understanding of the complex web of life and the role that mushrooms play within it.
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Fungi and animals share a common ancestor
Mushrooms and, by extension, fungi, share a closer genetic relationship with humans than with plants. While mushrooms do not contain human DNA, they do share nearly 50% of their DNA with humans, according to mycologist and author Paul Stamets. This is because fungi and animals share a common ancestor.
Fungi and animals are both Opisthokonts, which means they share a more recent common ancestor with each other than they do with plants. This was discovered in the 1950s, and later confirmed by scientists. Fungi and animals share genetic characteristics that plants do not have, such as the use of the polysaccharide chitin to build cell walls. Plants, on the other hand, use cellulose.
Another similarity between mushrooms and humans is that they both produce vitamin D when exposed to sunlight. Furthermore, both mushrooms and humans store carbohydrate energy as glycogen, whereas plants store energy in the form of starch.
The close relationship between mushrooms and humans may explain the meaty taste of mushrooms, according to some. However, this has not been proven, and the variety of flavours among different mushroom species makes it difficult to draw a definitive conclusion.
Despite their distant relationship, animals and fungi have diverged significantly from one another over time. A recent study found that the genomic features characteristic of both groups arose even before the origin of the animal and fungi kingdoms.
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Mushrooms and humans both use polysaccharides
Mushrooms and humans share nearly 50% of their DNA with fungi, according to Paul Stamets, a mycologist and author. This is because fungi and animals share genetic characteristics that plants do not have. One of the most well-known components of mushrooms is their polysaccharide content. Polysaccharides are carbohydrates, or chains of sugars, made up of carbon, hydrogen, and oxygen atoms.
Mushrooms contain a variety of polysaccharides, including alpha- and beta-glucans. Beta-glucans, in particular, have been found to support and activate the body's immune response to fight off infections by stimulating both the innate and adaptive immune systems. They have also been proposed as a "nutritional fuel" for the immune system.
The health benefits of mushroom polysaccharides have been observed in studies on rodents and humans. For example, a purified polysaccharide isolated from an aqueous extract of Ganoderma lucidum mushroom (also known as Lingzhi or Reishi medicinal mushrooms) was injected into mice, and the results showed improved antifatigue symptoms. Another study found that dietary consumption of Agaricus bisporus mushrooms reduced diabetes risk factors, suggesting that these mushrooms contain compounds with potential anti-inflammatory and antioxidant health benefits.
Mushrooms also possess unique protein complexes that interact with human cells to provide healing abilities. They form symbiotic relationships with plant roots, trading nutrients for carbohydrates, and have the capacity to connect disparate life forms through cooperative networks. This demonstrates the power of symbiosis for mutual survival, which has been recognized by ancient cultures that revered mushrooms for their psychedelic compounds and ability to induce dream-like states.
In summary, mushrooms and humans both utilize polysaccharides, which are carbohydrates that provide an energy source when consumed. Polysaccharides in mushrooms have been found to offer a range of health benefits, including potential anti-inflammatory, antioxidant, antitumor, antiviral, and anti-carcinogenic properties. These findings have prompted further research into the potential therapeutic applications of mushroom polysaccharides for human health and wellness.
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Mushrooms are more closely related to humans than plants
Further evidence for this comes from the observation that fungi and animals share genetic characteristics that plants do not have. For example, both mushrooms and humans store carbohydrate energy as glycogen, while plants use starch. Fungi and insects use chitin to build cell walls, while plants use cellulose. And mushrooms, like humans, produce vitamin D when exposed to sunlight.
This genetic relatedness has important implications for human health. For instance, oral antifungals can be dangerous because of the similarity between human and fungal DNA. However, understanding the similarities between human and fungal DNA can also lead to medical breakthroughs. For example, by studying the natural immunities that fungi have developed, we may be able to extract treatments to help humans fight off viruses.
In addition to their genetic similarities, mushrooms and humans also share a capacity for connection and symbiosis. Mushrooms form vital symbiotic relationships with plant roots through their mycelial networks, acting as "nature's internet" and allowing information and resources to flow between diverse species. Similarly, humans form social bonds and commune with each other and the natural world. Ancient cultures also revered mushrooms for their psychedelic compounds and ability to induce dreamlike states, which may have facilitated spiritual exploration and connection.
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Frequently asked questions
No, mushrooms do not have human DNA. However, mushrooms are more closely related to humans than to plants. Humans share nearly 50% of their DNA with fungi.
Mushrooms and humans have a lot in common. They both store carbohydrate energy as glycogen, produce vitamin D when exposed to sunlight, and use the polysaccharide chitin to build cell walls.
Mushrooms contain a neurotransmitter called glutamate, which is also found in meats and other savory foods. This gives mushrooms their distinct umami flavor.

























