
Magic mushrooms, also known as psilocybin mushrooms, have been used by people living with cluster headaches to treat head pain and headache frequency. While the use of psilocybin to treat headaches is not officially recognized, many people in the cluster headache community have reported that microdosing psilocybin mushrooms can alleviate pain and reduce the frequency of attacks. Researchers are now conducting controlled trials to document the effects of psilocybin on cluster headaches, with some preliminary studies confirming the positive effects of psilocybin on headache pain and frequency. However, the use of psilocybin for headache treatment remains controversial, with some experts arguing that the reported relief may be due to the placebo effect or natural remission.
| Characteristics | Values |
|---|---|
| Types of Mushrooms | Psilocybin, Magic Mushrooms |
| Types of Headaches | Cluster Headaches, Migraines |
| Dosage | Microdosing, Medium-Sized Mushroom |
| Effectiveness | May Reduce Pain and Attack Frequency, May Not Work for Full-Blown Migraines |
| Legality | Schedule I Substance, Class A Offence in the UK |
| Side Effects | No Detox Effect, No Proven Physical Addiction |
| Research | Limited Controlled Studies, More Research Needed |
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What You'll Learn
- Magic mushrooms have been used to treat cluster headaches
- Psilocybin mushrooms are classified as a Schedule I substance
- Microdosing is the practice of taking small, regular doses
- Anecdotal evidence suggests mushrooms improve overall capacity
- Controlled studies have yielded no conclusions about psilocybin

Magic mushrooms have been used to treat cluster headaches
Magic mushrooms, or mushrooms containing the psychedelic compound psilocybin, have been used by people living with cluster headaches to treat head pain and headache frequency. While psilocybin has never been officially recognized as a treatment for cluster headaches, many in the cluster headache community have reported that microdosing psilocybin mushrooms can alleviate pain and reduce the frequency of attacks.
In 2006, the medical journal Neurology published a study titled "Response of cluster headache to psilocybin and LSD," which interviewed 53 cluster headache sufferers about their use of magic mushrooms and LSD to treat their condition. The study found that 22 out of 26 psilocybin users reported aborted attacks, and 25 out of 48 reported cluster cycle termination. Additionally, 18 out of 19 psilocybin users and 4 out of 5 LSD users reported extended remission.
Several individuals have shared their positive experiences with using magic mushrooms to treat their cluster headaches. One person reported that taking magic mushrooms enabled them to lead a normal life, allowing them to hold down a job. Another individual shared that since incorporating mushrooms, the intensity of their headaches had decreased by a third, and the remissions between attacks had lengthened to 40 days.
Despite these anecdotal reports, the effectiveness of magic mushrooms in treating cluster headaches remains controversial. Some experts argue that the relief reported by patients may be due to a placebo effect or natural remission. However, the promising results from preliminary studies and personal testimonies have sparked renewed interest in researching psychedelics like psilocybin for treating various conditions, including cluster headaches. Researchers are hopeful that future studies will help clarify the therapeutic mechanism behind the long-lasting effects of psilocybin and lead to the development of more effective treatments for this debilitating condition.
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Psilocybin mushrooms are classified as a Schedule I substance
While there have been reports of people using magic mushrooms to relieve headaches, the use of psilocybin mushrooms, also known as magic mushrooms, is controversial. Psilocybin is a Schedule I controlled substance under the 1971 United Nations Convention on Psychotropic Substances. This means that it is considered to have a high potential for abuse and no recognized medical uses. However, psilocybin mushrooms have been used medicinally and religiously in many cultures throughout history, and some people claim that they can be effective in treating headaches.
The classification of psilocybin mushrooms as a Schedule I substance has been controversial, as some people argue that they have legitimate medical and therapeutic uses. There has been a renewed interest in researching the potential benefits of psilocybin for treating various diseases and disorders, including anxiety, depression, addiction, and PTSD. Some preliminary studies have suggested that psilocybin may be effective in reducing the frequency and intensity of cluster headaches when taken in low doses. However, more research is needed to understand the therapeutic mechanism behind these effects and to determine the potential risks and benefits of using psilocybin mushrooms for medical purposes.
The legal status of psilocybin mushrooms varies across different jurisdictions. While they are illegal to possess or use without authorization in many countries, some regions have adopted a more permissive approach. For example, in the US, the regulations differ across states, with some states specifically prohibiting the sale and possession of psilocybin mushroom spores while others do not consider growing psilocybin mushrooms as "manufacturing" a controlled substance. Similarly, in countries like the Netherlands, authorities focus on promoting the safe use of psychedelic drugs, including psilocybin, to reduce potential harm.
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Microdosing is the practice of taking small, regular doses
Psilocybin mushrooms, often referred to as "magic mushrooms", have been anecdotally reported to alleviate pain and reduce the frequency of cluster headache attacks. Cluster headaches are considered one of the most excruciating forms of head pain, with up to 25% of sufferers considering suicide due to the severity of their condition. While there is limited scientific research on the effectiveness of psilocybin for cluster headaches, some preliminary studies and anecdotal reports suggest potential benefits.
One preliminary study published in "Headache" found that psilocybin mushrooms could relieve cluster headache pain and reduce attack frequency. Additionally, a survey of 53 cluster headache sufferers at Harvard McClean Hospital showed promising results, with 22 out of 26 psilocybin users reporting aborted attacks and 18 out of 19 psilocybin users reporting extended remission.
Microdosing psilocybin mushrooms typically involves taking small doses at regular intervals, such as every four days. Some individuals adjust their dosage and timing based on their headache patterns and preferences. For example, if an individual wakes up with a full-blown migraine, they may opt to take a strong painkiller instead of mushrooms. It is important to note that the effectiveness of microdosing may vary among individuals, and there is no one-size-fits-all approach.
While microdosing psilocybin mushrooms has shown potential in alleviating cluster headaches, it is important to approach this practice with caution. Psilocybin mushrooms are considered a Schedule I substance by the federal Drug Enforcement Agency, indicating no currently accepted medical use and a high potential for abuse. Additionally, possession and sale penalties vary by state, and in some places, it is illegal. Therefore, individuals considering microdosing should stay informed about the legal status and potential risks associated with psilocybin mushrooms.
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Anecdotal evidence suggests mushrooms improve overall capacity
While there is some evidence to suggest that psilocybin mushrooms can help alleviate pain and reduce the frequency of cluster headaches, this has not been officially recognized as a treatment. However, many people with chronic cluster headaches have reported experiencing relief from their symptoms after consuming psilocybin mushrooms, also known as "magic mushrooms."
Psilocybin mushrooms have been used by people living with cluster headaches for over 20 years, and while there has been renewed interest in researching their therapeutic potential, controlled studies on the topic are limited. In a preliminary study published in "Headache," researchers confirmed that psilocybin mushrooms could indeed relieve cluster headache pain and reduce attack frequency.
Despite the lack of extensive clinical research, anecdotal evidence and personal testimonies abound. One individual shared their experience in "New York Magazine," detailing how psychedelic mushrooms helped cure their cluster headaches. They described the excruciating pain and the sense of desperation that led them to explore alternative treatments, ultimately finding relief through psilocybin.
Another individual, Richard Ayliffe, shared his story with The Guardian, explaining how magic mushrooms have enabled him to lead a normal life, free from the debilitating symptoms of chronic cluster headaches. He tried conventional treatments without success and now faces the difficult choice between breaking the law and finding relief through mushrooms or forgoing the treatment altogether.
While these personal accounts provide compelling reasons to further explore the potential of psilocybin mushrooms in treating cluster headaches, it's important to approach them with caution. Dr. Peter Goadsby, a leading expert on cluster headaches, acknowledges the reported relief but suggests it could be a placebo effect or natural remission. Nonetheless, he believes that the positive experiences reported by patients warrant proper clinical studies to thoroughly investigate the effects of psilocybin mushrooms on cluster headaches.
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Controlled studies have yielded no conclusions about psilocybin
While psilocybin mushrooms have been used to treat headaches for over 20 years, there is still no consensus on their effectiveness. Controlled studies have yielded no conclusions about psilocybin, and its status as a Schedule I substance—defined as having "no currently accepted medical use and a high potential for abuse"—has made researching its efficacy challenging.
In a preliminary study published in "Headache", researchers confirmed that psilocybin mushrooms can relieve cluster headache pain and reduce attack frequency. However, this study was not a controlled trial, and Dr. Schindler, who led the research, encourages future investigations to include multiple rounds of treatment to better evaluate psilocybin's effects over time.
The medical community remains divided on the role of psilocybin in headache treatment. Some neurologists and headache specialists acknowledge the potential of psilocybin but stop short of recommending it due to its legal status and the lack of conclusive evidence from controlled studies. They emphasize the need for rigorous clinical trials to determine its effectiveness and safety.
On the other hand, some headache sufferers have taken matters into their own hands, flouting drug laws to access psilocybin mushrooms. They report significant relief from their headaches and are willing to risk legal consequences to maintain their treatment. These personal testimonies and case reports further fuel the interest in researching psilocybin for headache treatment.
While controlled studies have not yet provided conclusive evidence, the preliminary findings and anecdotal reports suggest that psilocybin mushrooms may offer a promising direction for headache treatment. Further well-designed, controlled investigations are necessary to confirm these preliminary findings and establish the role of psilocybin in headache management.
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Frequently asked questions
According to some reports, ingesting small amounts of LSD, psilocybin (a hallucinogenic compound found in some mushrooms), or DMT can reduce pain and interrupt cluster headache cycles. However, psilocybin has never been officially recognized as a treatment for cluster headaches.
Some people take tiny doses of psychedelic mushrooms, also known as microdosing. Microdosing is taking small, regular doses of a drug, in this case, mushrooms, to achieve a desired effect.
While there has been no proven physical addiction to psychedelics like mushrooms or LSD, it is possible to build up a tolerance. Some people have also reported feeling like they had a hangover the next day after taking too high a dose.

























