
Psilocybin mushrooms, commonly known as magic mushrooms, are a type of hallucinogenic mushroom that contains the prodrug psilocybin, which turns into the psychedelic compound psilocin upon ingestion. While psilocybin mushrooms are primarily known for their psychoactive effects, there is interest in understanding their nutritional value and potential health benefits. This includes exploring their ability to positively impact mental health conditions such as depression and PTSD.
| Characteristics | Values |
|---|---|
| Effects | Hallucinations, sound and sight disturbance, muscle weakness, drowsiness, nausea, vomiting, euphoria, muscle relaxation, lack of coordination |
| Psychedelic compound | Psilocybin |
| Psychedelic effects | Caused by psilocin |
| Short-term increases in tolerance | Yes |
| Physical or psychological dependence | No |
| Timing of effects | Around 20 minutes after ingestion |
| Duration of effects | Up to 6 hours |
| Positive effects on mental health | Yes |
| Treatment | PTSD, headaches, substance misuse disorders, depression |
| Nutritional value | Potassium, vitamin D, B vitamins, selenium, protein, minerals, antioxidants |
| Health benefits | Support heart health, immune function, reduce inflammation, boost cognitive health, prevent cancer |
| Nutritional value of vitamin D2-enhanced mushrooms | Decrease in PAI-1 concentration, increase in total 25(OH)D concentration |
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What You'll Learn

Vitamin D content
Mushrooms are a nutritious food item that contains protein, vitamins, minerals, and antioxidants. They are also a good source of folate during pregnancy. Some studies have found that certain types of mushrooms, such as Lion's Mane, can improve brain cell growth and memory.
Psilocybin mushrooms, commonly known as magic mushrooms or shrooms, are a type of hallucinogenic mushroom that contains the prodrug psilocybin. When ingested, psilocybin is broken down by the liver and converted into psilocin, which is responsible for the psychedelic effects of these mushrooms. Psilocybin mushrooms are often used as recreational drugs and have been a part of various cultures for thousands of years.
While psilocybin mushrooms are primarily known for their psychoactive properties, they do contribute to vitamin D intake. Vitamin D is essential for maintaining healthy bones, teeth, and muscles, and it also plays a role in regulating mood and immune function.
The vitamin D content in mushrooms can vary depending on their exposure to sunlight or UV light. Sliced mushrooms have more surface area exposed to sunlight, increasing their vitamin D content. Wild mushrooms tend to have higher levels of vitamin D compared to commercially produced ones, but the vitamin D content in commercially produced mushrooms can be significantly increased by exposing them to sunlight or UV light.
It is worth noting that the vitamin D content in mushrooms is generally considered to be small. However, the specific amount of vitamin D in psilocybin mushrooms may vary depending on the species, growing conditions, and other factors. Overall, while psilocybin mushrooms may contribute to vitamin D intake, they should not be solely relied upon as a primary source of this nutrient.
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Cancer prevention
Although psilocybin mushrooms are known for their hallucinogenic effects, they may also offer nutritional value and health benefits. However, it is important to note that psilocybin mushrooms are classified as a controlled substance in many places, and their possession or consumption may be illegal. Therefore, it is essential to follow local laws and regulations regarding their use.
Mushrooms, in general, are a good source of various vitamins, minerals, and antioxidants. They contain vitamin D, vitamin B6, selenium, zinc, riboflavin, niacin, and pantothenic acid, and potassium. These nutrients contribute to heart health, immune function, and cognitive health. Some mushrooms, like lion's mane, are specifically known for their potential brain health benefits.
When it comes to cancer prevention, mushrooms have been studied for their potential anticancer properties. Here are some ways in which mushrooms may contribute to cancer prevention:
- Antioxidants and Anti-inflammatory Properties: Mushrooms contain antioxidants that help protect the body from stress and prevent or slow cell damage caused by chronic inflammation. This includes the antioxidant choline, which some studies suggest may reduce the risk of certain types of cancer. However, there are conflicting findings, as one study indicated a potential increased risk of lethal prostate cancer associated with choline intake.
- Immunomodulating Effects: Mushrooms are known for their immunomodulating properties, meaning they can enhance the immune system. A strong immune system is crucial in cancer prevention and the body's defence against tumour growth.
- Anticancer Compounds: Certain compounds in mushrooms, such as beta glucan, have been found to act as prebiotics, promoting the growth of beneficial gut bacteria. A healthy gut plays a role in maintaining immune defences, which can help in cancer prevention. Additionally, beta glucan has been linked to potential antitumor activity.
- Cancer-Specific Prevention: Specific types of mushrooms have been studied for their potential cancer-specific preventive effects. For example, Trametes versicolor has been shown to inhibit the growth of several human cancer cell lines and act as an adjuvant in breast cancer prevention. Grifola frondosa is promoted as an anticancer agent, particularly for human gastric carcinoma, by inducing cell apoptosis and accelerating anticancer activity.
- Nutritional Value: Mushrooms provide nutritional value that may contribute to overall health and cancer prevention. They are low in calories, sodium, and cholesterol, making them a healthy substitute for meat. This nutritional profile may help maintain a healthy weight, which is a factor in cancer prevention.
While these potential cancer prevention properties of mushrooms are promising, it is important to note that further research is needed to confirm these effects. The studies mentioned involve various types of mushrooms, and the specific effects may vary between different species. Additionally, it is always advisable to consult with a healthcare professional before incorporating any new dietary or medicinal components, especially when considering substances like psilocybin mushrooms, which may have legal restrictions.
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Neurodegenerative diseases
While psilocybin mushrooms are known for their hallucinogenic effects, there is growing interest in their potential therapeutic benefits. Research suggests that psilocybin mushrooms may have neuroprotective properties that can help in the management and treatment of neurodegenerative diseases.
Mushrooms, including those with psilocybin, contain bioactive compounds that exhibit therapeutic properties. These compounds, such as alkaloids, polyphenols, and terpenoids, have been found to reduce neurotoxicity and exhibit anti-inflammatory and antioxidant effects. For example, studies have shown that the alkaloid corallocins, isolated from the mushroom Hericium coralloides, can stimulate the expression of neurotrophins, which are essential for brain health.
Additionally, mushrooms like Lion's Mane, Reishi, and Hericium erinaceus are thought to have neuroprotective and neuroregenerative properties. They may improve cognitive functions and play a role in preventing or slowing down age-related neurological dysfunctions associated with Alzheimer's and Parkinson's diseases.
While the research is still ongoing, the potential of psilocybin mushrooms and other medicinal varieties in the field of neurodegenerative diseases is promising. These mushrooms may offer a natural and alternative approach to managing and treating these debilitating conditions.
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Positives for mental health
Psilocybin mushrooms, commonly known as magic mushrooms, are hallucinogenic mushrooms that contain the prodrug psilocybin. When ingested, psilocybin is metabolized to produce psilocin, the active form of the compound. Psilocybin has been used for recreational purposes and has also been explored for its potential therapeutic benefits in treating various mental health disorders.
Treatment of Psychiatric Disorders:
Psilocybin has shown potential in the treatment of various psychiatric conditions, including depression. When administered in controlled conditions with supportive therapy, psilocybin may help treat psychiatric disorders. Research suggests that psilocybin can lead to positive changes in attitude, mood, and behavior. It appears to elevate a personality trait known as "openness," which includes sensitivity, imagination, and an appreciation for the values and viewpoints of others.
Smoking Cessation:
Psilocybin has demonstrated positive results in smoking cessation studies. The National Institute of Health awarded Johns Hopkins a grant to explore psilocybin's potential as a smoking cessation tool, indicating its promising prospects in this area.
Eating Disorders:
Preliminary studies have shown encouraging results in using psilocybin therapy for patients with anorexia nervosa, warranting further investigation in larger-scale clinical trials.
Safe and Non-Addictive:
Psilocybin has been found to be extremely safe when administered in controlled settings. It does not cause physical or psychological dependence, and the more often it is taken within a short period, the weaker the effects become, making it difficult to misuse.
Treatment of Anxiety and OCD:
Psilocybin has been studied for its potential in treating anxiety disorders and obsessive-compulsive disorder (OCD). Its ability to interact with serotonin receptors in the brain may contribute to its therapeutic effects in these areas.
Positive and Meaningful Experiences:
In controlled studies, participants reported significantly increased ratings of positive attitudes, mood, social effects, and behavior after psilocybin sessions. Many patients described their psilocybin experience as one of the most meaningful experiences of their lives, which could enhance patient buy-in and satisfaction with treatment.
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Risks of overdose
Psilocybin mushrooms, commonly known as magic mushrooms or shrooms, are a type of hallucinogenic mushroom that contains the prodrug psilocybin. When ingested, psilocybin is broken down by the liver and converted into the psychedelic compound psilocin, which is responsible for the mushrooms' psychological effects.
While psilocybin mushrooms are considered physiologically safe relative to other psychoactive drugs, with no evidence of organ damage or addiction potential, there are still risks associated with their consumption, particularly in the case of an overdose.
The risks of a psilocybin mushroom overdose can vary depending on the individual and the amount consumed. The psychological effects of psilocybin can induce adverse reactions, even in moderate doses. These reactions may include:
- Anxiety
- Disorientation
- Fear
- Grief
- Paranoia
- Panic attacks
- Psychosis
- Trip-induced psychosis
In addition to the psychological effects, a psilocybin mushroom overdose can also result in physical symptoms such as:
- Nausea
- Vomiting
- Euphoria
- Muscle weakness or relaxation
- Drowsiness
- Lack of coordination
- Shivering
- Abdominal pain
- Increased heart rate and blood pressure
While fatal overdoses from psilocybin mushrooms are rare, they are possible. Significantly elevated levels of psilocin can overstimulate the 5-HT2A receptors in the brain, leading to acute serotonin syndrome. Additionally, fatal events related to emotional distress and trip-induced psychosis have been reported as a result of overconsumption of psilocybin mushrooms.
It is important to note that the dosage of psilocybin-containing mushrooms can vary significantly between species and even within the same species, making it difficult to estimate the exact amount required for an overdose. Therefore, it is crucial to exercise caution when consuming psilocybin mushrooms to avoid any potential risks associated with overdose.
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Frequently asked questions
Yes, psilocybin mushrooms are a type of hallucinogenic mushroom that causes hallucinations, sound and sight disturbances, muscle weakness, drowsiness, nausea, euphoria, and lack of coordination.
Psilocybin mushrooms have not been known to cause physical or psychological dependence (addiction). The more often they are taken within a short period, the weaker the resultant effects are.
Psilocybin mushrooms are classified as a class A drug and are illegal to possess, give away, or sell in the UK. In the US, they are a Schedule I substance and are illegal to use.
Psilocybin mushrooms contain the prodrug psilocybin, which turns into the psychedelic psilocin upon ingestion. They do not seem to contain the nutrients found in other mushrooms, such as vitamins, minerals, and antioxidants.

























