
Mushrooms are a popular food choice, especially for vegetarians, but they can be tough on the stomach. Some people experience stomach aches, vomiting, and diarrhea after consuming mushrooms. This could be due to the presence of chitin, a polysaccharide that is difficult for the human body to digest. Chitin is found in the cell walls of mushrooms and can cause gastrointestinal irritation and intestinal obstruction in extreme cases. Other possible causes of mushroom-related stomach issues include food allergies, mild poisoning, or the presence of toxins and bacteria in wild mushrooms. It is recommended to consume no more than 200-300 grams of fresh mushrooms per week and to avoid raw mushrooms, as cooking can destroy certain toxins.
| Characteristics | Values |
|---|---|
| Cause of stomach upset | Chitin, a polysaccharide found in the cell walls of fungi, insects, and other organisms |
| Other causes | Mannitol and trehalose (two carbohydrates that are difficult to digest), protein, toxins, bacteria, pollutants like radioactive substances or heavy metals |
| Symptoms | Stomach pain, vomiting, diarrhea, drowsiness, confusion, nausea, blood disorders, seizures, liver and kidney damage |
| Prevention | Chew well, consume no more than 200g to 300g of fresh mushrooms per week, cook thoroughly, avoid raw mushrooms, avoid wild mushrooms |
| Treatment | Call the Poison Control Center at 1-800-222-1222, consult a healthcare professional |
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What You'll Learn

Magic mushrooms and stomach problems
Magic mushrooms can cause various negative side effects, including gastrointestinal issues. The most common stomach problems associated with magic mushroom consumption are nausea, vomiting, and stomach pain. Other possible side effects include anxiety, paranoia, confusion, disorientation, panic attacks, psychotic reactions, and seizures.
The negative side effects of magic mushrooms can be influenced by several factors, such as dose, environment, mood, and the mental health of the individual. Additionally, the preparation and cleanliness of the mushrooms can also impact the likelihood of experiencing stomach problems. Improperly prepared mushrooms may contain dirt, bacteria, or other contaminants that can irritate the gastrointestinal tract and cause stomach discomfort.
Chitin, a substance found in both insects and mushrooms, is believed to be a significant contributor to stomach problems associated with mushroom consumption. Chitin is an indigestible polysaccharide that can trigger inflammation and immune responses in the body. Cooking mushrooms breaks down chitin, making them easier to digest. However, individuals who consume raw or undercooked mushrooms may experience more stomach problems due to the presence of chitin.
To reduce the likelihood of stomach problems when consuming magic mushrooms, it is recommended to properly prepare and clean the mushrooms before consumption. Grinding and powdering dried mushrooms can also help ease the burden on the stomach by mechanically breaking down the chitinous mushroom flesh. Additionally, consuming lemon juice along with the mushrooms can aid in digestion, as its acidic environment partially converts psilocybin to psilocin, a process that also occurs in the stomach.
It is important to note that the negative side effects of magic mushrooms can vary significantly from person to person, and some individuals may be more sensitive to the gastrointestinal effects. If you experience stomach problems after consuming magic mushrooms, it is recommended to seek medical advice and explore alternative preparation methods to find one that suits your individual needs.
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Poisonous mushrooms
Of the 10,000 known species of large mushrooms, only around 300 are edible. The vast majority of mushroom-related deaths are caused by species in the genus Amanita, which are often mistaken for edible mushrooms. For example, the "death cap" mushroom closely resembles edible straw mushrooms and Caesar's mushrooms, and its heat-stable amatoxins are not destroyed by cooking. Other deadly Amanita species include Amanita virosa, or the "destroying angel", and Amanita phalloides, which resembles the Asian paddy-straw mushroom.
Symptoms of mushroom poisoning range from an upset stomach, drowsiness, and confusion to heart, liver, and kidney damage. The symptoms may occur soon after eating or can be delayed for up to several days. The majority of deaths from poisonous mushrooms are caused by Amanitas or "death caps". Death caps do not have a distinct taste or smell, and symptoms from consuming them are typically delayed for 6 to 24 hours. Other poisonous mushrooms include false morels, which can cause vomiting, diarrhoea, cramps, kidney failure, and death.
To prevent mushroom poisoning, it is important to correctly identify mushrooms before consuming them. Mushroom gatherers should familiarise themselves with the mushrooms they intend to collect, as well as with any similar-looking toxic species. It is also recommended to consume no more than 200 to 300 grams of fresh mushrooms per week to avoid the risk of overexposure to harmful substances that may accumulate in mushrooms from the environment.
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Edible mushrooms causing sickness
Mushrooms are a delicious and nutritious addition to many dishes, but they can sometimes cause sickness, even if they are edible. There are around 10,000 known species of large mushrooms, but only about 300 are considered edible. Even these edible varieties can cause illness if not handled, cooked, or consumed properly.
Firstly, it is important to identify mushrooms with absolute certainty before consuming them. Many poisonous mushrooms closely resemble edible ones, and misidentification is a common cause of mushroom poisoning. For example, the "chicken of the woods" or sulphur shelf (Laetiporus sulphureus) is considered edible if gathered from hardwood trees, but those from conifers or locusts are toxic. Similarly, the Coprinus genus, or "inky caps", is generally edible, but they can cause an adverse reaction when consumed with alcohol. This is because coprine interferes with how the body processes alcohol, which can lead to an unpleasant illness.
Secondly, some edible mushrooms are only safe to eat when cooked. For instance, true morels (Morchella spp.) are generally safe to eat if cooked thoroughly, but eating them raw can cause gastric upset. Other mushrooms, such as the Gyromitra esculenta, Verpa conica, and Verpa bohemica, are commonly mistaken for true morels, but they can have deadly results. These false morels often cause vomiting, diarrhoea, and cramps, and can even lead to kidney failure and death.
Thirdly, the way mushrooms are handled and prepared is crucial. They should be cooked properly, and leftovers containing mushrooms should be reheated with caution. Mushrooms have thick cell walls, so the protein in their cells can only be absorbed if they are chewed well. It is also recommended to consume no more than 200-300 grams of fresh mushrooms per week to avoid the risk of exposure to harmful substances that may accumulate in mushrooms from the environment.
Lastly, some people may experience digestive problems after consuming mushrooms due to their individual physiology. Mushroom cell walls contain chitin, an indigestible fibre. Some people lack the enzyme needed to break down trehalose, another component of mushrooms. As a result, they may experience flatulence and diarrhoea after eating mushrooms.
In summary, while mushrooms are a tasty and nutritious food, it is important to take precautions when consuming them. Proper identification, handling, and cooking are essential to avoid illness. Additionally, individual tolerance to mushrooms varies, and some people may experience digestive issues even with edible varieties.
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Mushroom toxins
Mushroom poisoning, or toxicity, occurs after consuming mushrooms that contain toxins. While there are thousands of mushroom species, only about 100 are toxic, and 15-20 species are potentially lethal when ingested. The severity of mushroom poisoning depends on the geographic location where the mushroom is grown, growth conditions, the amount of toxin delivered, and the genetic characteristics of the mushroom.
Other toxins found in mushrooms include muscarine, psilocybin, muscimol, ibotenic acid, and coprine. Muscarine stimulates the muscarinic receptors of nerves and muscles, causing symptoms such as sweating, salivation, tears, blurred vision, palpitations, and respiratory failure in high doses. Psilocybin and psilocin-containing species can cause hallucinations, altered sensorium, and euphoria. Coprine causes a disulfiram-like reaction when combined with alcohol, leading to symptoms such as headache, nausea, vomiting, flushing, tachycardia, and hypotension.
In addition to these specific toxins, mushrooms can also accumulate harmful substances from the environment, such as radioactive substances or heavy metals. The indigestible dietary fibre chitin found in mushroom cell walls can also cause digestive problems, and some people may lack the enzyme needed to break down trehalose, another component of mushrooms.
To prevent mushroom poisoning, it is crucial to properly identify mushroom species before consumption and be aware of any potential toxic look-alikes. Cooking mushrooms may reduce toxicity in some cases, but it is important to note that boiling, cooking, freezing, or processing may not always alter the toxicity of certain mushrooms.
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Mushroom allergy
Although mushrooms are a versatile and widely consumed ingredient, enjoyed in various cuisines worldwide, they can trigger adverse reactions in some people, including allergic responses ranging from mild to severe. Mushroom allergies are relatively rare, but they can affect anyone, regardless of age or background. The overall extent of mushroom allergies is unknown, but it is believed to be slight, affecting around 1% of people who eat mushrooms. However, it could be as prevalent as pollen and mould allergies, affecting 10-30% of an allergic population.
Mushroom allergies occur when the immune system mistakenly identifies mushroom allergens, the proteins found in mushrooms, as harmful substances. This misidentification leads to an allergic reaction, which can manifest in various ways. While not everyone will have an allergic reaction to mushrooms, those who do may experience symptoms ranging from mild discomfort to life-threatening anaphylaxis. Specific examples include the cultivated mushroom, which has been linked to anaphylaxis due to the presence of mannitol and IgE-mediated allergies.
Common symptoms of a mushroom allergy include itching, hives, swelling of the lips, face, or throat, and gastrointestinal distress such as nausea, vomiting, or diarrhoea. These symptoms may appear shortly after consuming mushrooms or inhaling mushroom spores. Inhaling airborne mushroom spores can lead to a respiratory allergy, causing symptoms such as sneezing, coughing, wheezing, and shortness of breath. These symptoms can be particularly problematic for individuals with pre-existing respiratory conditions like asthma.
Certain factors may increase the likelihood of developing a mushroom allergy. These include a family history of allergies, existing food allergies, or a predisposition to allergic conditions such as asthma, eczema, or mould allergy due to potential cross-reactivity between mushroom proteins and moulds.
The most effective way to manage a mushroom allergy is to avoid consuming or coming into close contact with edible mushrooms and their spores. If you suspect that you have a mushroom allergy, it is recommended to seek a professional diagnosis from an allergist, who can perform tests such as skin prick tests or blood tests to determine if you have an allergy to mushrooms.
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Frequently asked questions
Mushrooms contain chitin, a polysaccharide that is difficult for the human body to digest. Chitin can cause gastrointestinal irritation, resulting in stomach upset, gas, bloating, diarrhoea, or constipation. Some people also have mushroom allergies or are sensitive to the proteins in mushrooms.
Raw mushrooms are harder to digest than cooked mushrooms because the act of cooking breaks down chitin. However, some people report that cooked mushrooms cause them more stomach pain than raw mushrooms.
No, some types of mushrooms are more likely to cause stomach upset than others. For example, button mushrooms, shiitake, oyster, and king trumpet mushrooms can be eaten raw and are less likely to cause issues. On the other hand, morels, chanterelles, and honey mushrooms are known to cause stomach upset in some people.
Yes, it is recommended to consume no more than 200g to 300g of fresh mushrooms per week. It is also important to properly identify mushrooms and cook them thoroughly before consuming them, as some wild mushrooms can be toxic.
If you experience mild digestive discomfort after consuming mushrooms, it is recommended to wait and observe your symptoms. If the discomfort persists or becomes more severe, consult a healthcare professional to rule out infection, intolerance, or other digestive conditions.

























