
Mushrooms are a type of fungus that can be found almost anywhere in the world. While some mushrooms are edible, others are toxic and can cause mushroom poisoning, which can lead to death. The number of mushroom-related deaths per year varies depending on the source and region. In the United States, according to the American Association of Poison Control Centers (AAPCC), there were 7 deaths from poisonous mushrooms in 2012, while another source estimates an average of about 3 deaths per year over a ten-year period from 2012 to 2020. Globally, it is estimated that there are about 100 mushroom-related deaths per year, with Amanita phalloides, also known as the death cap, being the most poisonous mushroom and responsible for the majority of fatal mushroom poisonings.
| Characteristics | Values |
|---|---|
| Number of deaths per year in the US | 3 on average over a 10-year period (2012-2020) |
| Number of deaths per year globally | 100 estimated |
| Number of deaths in China in 2019 | 22 |
| Number of deaths in 2012 | 7 |
| Number of deaths in 2010 | 1 |
| Number of deaths in 2011 | Unknown, but higher than 2010 |
| Most deadly mushroom | Amanita phalloides (death cap) |
| Percentage of mushroom-related fatalities attributed to Amanita phalloides | 90% |
| Estimated toxicity of Amanita phalloides | 30 grams or half a cap is enough to kill a human |
| Average time until symptoms of death cap toxicity | 6 to 12 hours after ingestion |
| Symptoms of death cap toxicity | Nausea, vomiting, jaundice, seizures, coma, and death |
| Mortality rate of death cap ingestion | 10-30% |
| Average time until death after ingestion of a toxic mushroom | 10 days |
| Mortality rate of patients hospitalized within 60 hours of ingestion of amanitin-containing mushrooms | 50-90% |
| Mortality rate of patients hospitalized almost immediately after ingestion of amanitin-containing mushrooms | 10% |
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What You'll Learn
- Global deaths from mushroom poisoning are estimated to be 100 per year
- Amanita phalloides, the most poisonous mushroom, causes 90% of mushroom fatalities
- Death cap mushrooms are responsible for the majority of fatal mushroom poisonings
- In the US, 3 people die per year from mushroom poisoning
- In China, mushroom poisoning is a serious food safety issue, causing many deaths

Global deaths from mushroom poisoning are estimated to be 100 per year
Poisonous mushrooms are a serious health concern, and according to some estimates, they cause about 100 deaths annually worldwide. While this number may vary, it highlights the dangers of consuming certain types of mushrooms. Mushroom poisoning occurs when toxic mushrooms are ingested, and it can lead to severe health issues and even death.
The symptoms of mushroom poisoning can range from mild gastrointestinal discomfort to organ failure and death. The toxicity of mushrooms depends on the presence of secondary metabolites produced by the fungus. These toxins can cause damage to vital organs, such as the liver and kidneys, leading to mortality. The mortality rate for mushroom poisoning has decreased over the years due to advancements in medical care, but it still remains a significant risk.
Mushroom poisoning is often a result of misidentification, where toxic mushrooms are mistaken for edible species. This is particularly common when the toxic mushrooms closely resemble edible ones in terms of colour and morphology. Certain types of mushrooms, such as Amanita phalloides, also known as death caps, are highly poisonous and have been responsible for a significant number of fatalities worldwide. Death caps, for instance, are estimated to be responsible for 90% of mushroom-related deaths annually.
To prevent mushroom poisoning, it is crucial to accurately identify mushrooms before consumption. Familiarizing oneself with both edible and toxic mushroom species is essential. Additionally, consuming wild mushrooms without proper knowledge can be dangerous. In regions like China, mushroom poisoning has become one of the most serious food safety issues, contributing to a significant proportion of oral poisoning deaths.
While the global estimate of 100 deaths per year from mushroom poisoning provides a broad perspective, it is challenging to determine the exact number of fatalities. This is partly due to variations in reporting and the possibility of misattribution to other causes. Nevertheless, the development of potential antidotes, such as the ICG drug, offers hope in mitigating the deadly effects of poisonous mushrooms.
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Amanita phalloides, the most poisonous mushroom, causes 90% of mushroom fatalities
Mushroom poisoning is a result of consuming wild mushrooms that have been misidentified as edible. In the United States, mushroom poisoning kills an average of three people per year, according to the National Poison Data System (NPDS). Over a period of 18 years, NPDS recorded 52 fatalities, with most deaths caused by cyclopeptide-producing mushrooms. Globally, it is estimated that mushroom poisoning causes 100 deaths per year.
Amanita phalloides, commonly known as the death cap, is the most poisonous mushroom and is responsible for 90% of mushroom-related fatalities. It is a deadly poisonous basidiomycete fungus that originates in Europe but has spread to other parts of the world. The death cap has large fruiting bodies that appear in summer and autumn, with caps that are generally greenish, white, or dirty green in colour, and a white stipe and gills.
The principal toxic constituent of Amanita phalloides is α-amanitin, which causes liver and kidney failure. As little as half a mushroom contains enough toxin to kill an adult human. The toxin inhibits RNA polymerase II, disrupting the synthesis of mRNA, microRNA, and small nuclear RNA, leading to cell death. The liver is the first organ affected after absorption in the gastrointestinal tract, but other organs, especially the kidneys, are also susceptible.
Amanita phalloides is similar in appearance to several edible mushroom species, including the paddy straw mushroom and A. princeps, commonly known as "white Caesar". It has also been mistaken for edible puffballs or mature specimens of other edible Amanita species. This similarity in appearance increases the risk of accidental poisoning and has resulted in Amanita phalloides being responsible for the majority of human deaths from mushroom poisoning, including possible historical cases involving Roman Emperor Claudius and Holy Roman Emperor Charles VI.
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Death cap mushrooms are responsible for the majority of fatal mushroom poisonings
Mushroom poisoning is a serious issue, causing about 10,000 illnesses and an estimated 100 deaths globally each year. In the United States, mushroom poisoning kills an average of about 3 people a year, according to the National Poison Data System (NPDS) annual reports. However, some sources suggest the number could be as high as 60, while others estimate it to be closer to 10. The actual number is hard to pinpoint due to potential underreporting or misattribution to other causes.
Death cap mushrooms, or Amanita phalloides, are particularly deadly and are responsible for the majority of fatal mushroom poisonings. This species is the most poisonous of all known mushrooms, with just half a mushroom containing enough toxin to kill an adult human. It is estimated that 30 grams, or half a cap, can be fatal. The toxins primarily target the liver, causing liver and kidney failure, but other organs can also be affected. The mortality rate of ingestion is believed to be around 10-30%symptoms typically occurring 6 to 12 hours after consumption.
The death cap mushroom is easily mistaken for edible varieties, especially the paddy straw mushroom, which has a similar appearance. This similarity has led to poisonings among immigrants from East and Southeast Asia in Australia and the West Coast of the United States, as well as in Oregon and Canada. In Oregon, a Korean family required liver transplants after misidentifying the mushrooms, and in Canberra, Australia, two people died after consuming a meal containing death caps.
The lack of effective treatments for death cap poisonings has been a significant concern. However, recent research by Chinese and Australian scientists offers new hope, suggesting that a widely available FDA-approved drug may be effective in countering death cap mushroom poisoning. This discovery could potentially save lives not only from death caps but also from other poisonous mushroom species worldwide.
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In the US, 3 people die per year from mushroom poisoning
Mushroom poisoning is a rare but serious occurrence. It results from ingesting mushrooms that contain toxic substances, and symptoms can vary from slight gastrointestinal discomfort to death in about 10 days. While mushroom poisoning is more common in Europe, it does occur in North America, with an average of 3 deaths per year in the US.
The death cap (Amanita phalloides) is the most poisonous mushroom known and is responsible for the majority of fatal mushroom poisonings worldwide. It is estimated that just 30 grams (1.1 ounces), or half a cap, of this mushroom is enough to kill a human. The mortality rate of ingestion of the death cap mushroom is believed to be around 10–30%. The toxins of the death cap mushroom primarily target the liver, but other organs, such as the kidneys, are also affected. Symptoms of ingestion include nausea and vomiting, followed by jaundice, seizures, and coma, which can lead to death.
In North America, death cap poisoning has particularly affected Laotian and Hmong immigrants, as this mushroom can be easily confused with A. princeps ("white Caesar"), a popular mushroom in their native countries. Similarly, East and Southeast Asian immigrants in Australia and the West Coast of the US have been susceptible to death cap poisoning due to its resemblance to the edible paddy straw mushroom (Volvariella volvacea). In Oregon, four members of a Korean family required liver transplants after consuming death caps.
While the death cap is the most deadly mushroom, other species are also poisonous and can cause serious harm or death. For example, in 2012, four out of seven total deaths from mushroom poisoning in the US were attributed to a single incident where a housekeeper at a care home cooked wild Amanita mushrooms into a sauce. In addition, over 1,300 emergency room visits in the US in 2016 were attributed to poisonous mushroom ingestion, with about 9% of patients experiencing serious adverse outcomes.
It is important to note that mushroom poisoning is often a result of misidentification, as toxic mushrooms can closely resemble edible species in terms of colour and morphology. To prevent mushroom poisoning, it is crucial for mushroom gatherers to familiarize themselves with both edible mushrooms and similar-looking toxic species.
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In China, mushroom poisoning is a serious food safety issue, causing many deaths
Mushroom poisoning is a serious food safety issue in China, causing hundreds of deaths per year. From 2010 to 2020, there were 788 deaths from mushroom poisoning in China, with an average of 78.8 deaths per year. The number of deaths per year ranged from a low of 16 in 2023 to a high of 28 in 2022.
Mushroom poisoning is often the result of ingesting wild mushrooms that have been misidentified as edible. This is due to the close resemblance between some toxic and edible mushroom species in terms of colour and morphology. In China, there are over 480 known poisonous mushroom species, and this number continues to grow as new species are discovered. For example, in 2022, three new species were recorded as poisonous, and in 2023, 12 new species were identified.
The geographical distribution of mushroom poisoning incidents in China varies, but the highest incidence typically occurs in the southwest and central regions of the country. Within these regions, Yunnan, Hunan, Sichuan, Guizhou, and Hubei have been the most affected areas in recent years. The temporal distribution of mushroom poisoning incidents shows that they can occur at any time of year, but the peak season is typically summer through autumn, with most cases occurring between May and October.
To prevent mushroom poisoning, it is important for mushroom gatherers to familiarize themselves with both edible and toxic mushroom species. Health education is essential to reducing the incidence of mushroom poisoning, especially in high-risk regions like southwest China. Citizens are advised to refrain from collecting or consuming wild mushrooms, as the risks associated with ingesting toxic species can be life-threatening.
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Frequently asked questions
On average, about 3 people die each year in the United States from mushroom poisoning, according to the National Poison Data System (NPDS). However, some estimates place the number of fatalities between 10 and 60.
It is estimated that mushroom poisoning causes about 100 deaths each year worldwide. Amanita phalloides, also known as the death cap mushroom, is responsible for 90% of mushroom-related fatalities.
Death can occur within a week or a few days of consuming poisonous mushrooms. However, symptoms typically appear 6 to 12 hours after ingestion, and patients who receive treatment within 60 hours of ingestion have a lower mortality rate.

























