
Psilocybin, the main psychedelic ingredient in magic mushrooms, has gained attention for its therapeutic potential. The amount of psilocybin in a gram of mushrooms varies depending on the species and strain, ranging from 0.5% to 2% per gram. Psilocybe cubensis, a common species, typically contains around 1% psilocybin, meaning a gram of dried Psilocybe cubensis mushrooms contains approximately 10 milligrams of psilocybin. However, it's important to note that psilocybin content can vary within and between species, and factors like environment and state of mind can also influence the effects of psychedelic mushrooms.
| Characteristics | Values |
|---|---|
| Psilocybin content in 1 gram of dried Psilocybe cubensis mushrooms | 1% (10mg) |
| Psilocybin content between species and strains | 0.5–2% per gram |
| Average psilocybin content in dried Psilocybe cubensis mushrooms | ~1% per gram |
| Low dose | 0.1-1 gram |
| Medium dose | 1.75-3 grams |
| High dose | 3.5 grams |
| Ultra-high dose | 5 grams |
| Heroic dose | Over 5 grams |
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What You'll Learn

A low dose of 1 gram of magic mushrooms
At this dosage, users may experience a range of effects, including euphoria, relaxation, creative thinking, an altered perception of time, dizziness, lightheadedness, confusion, and nausea. It is worth noting that the effects of magic mushrooms can vary depending on the individual and their underlying mental health. Additionally, the environment and state of mind can also play a significant role in the effects of magic mushrooms.
It is recommended to start with a low dose and gradually increase the amount to ensure a positive and safe experience. When consuming magic mushrooms, it is crucial to follow safety guidelines, such as having a trusted source, knowing the species, and being in a comfortable and familiar setting.
Magic mushrooms are a broad category encompassing at least 300 different species of hallucinogenic mushrooms, most of which contain psilocybin and psilocin, the active compounds responsible for their mind-altering effects. Psilocybin and psilocin are tryptamine/indolamine hallucinogens that activate serotonin receptors in the brain, influencing mood and perception. While magic mushrooms have shown potential therapeutic benefits, such as disrupting connections in the brain associated with depression, anxiety, and substance use disorders, it is important to approach their use with caution and a thorough understanding of dosage and potential risks.
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A medium dose of 1.75 grams of dried mushrooms
Psilocybin mushrooms, commonly known as "magic mushrooms", contain the psychoactive substances psilocybin and psilocin. The psilocybin content of mushrooms varies between species and strains, ranging from 0.5 to 2% per gram. On average, there is approximately 1% psilocybin per gram of dried Psilocybe cubensis mushrooms, the most common species for psychedelic use. This equates to roughly 17.5 mg of psilocybin in 1.75 grams of dried mushrooms, considered a medium dose.
At this dosage, individuals typically experience some hallucinogenic and psychedelic effects, including open- and closed-eye visuals, synesthesia (blending of the senses), and heightened euphoria. However, the sense of self typically remains intact, and individuals may still be able to walk around and maintain their sense of identity. It is important to note that the effects of psilocybin mushrooms can vary depending on individual factors and the specific mushroom strain consumed.
When consuming psilocybin mushrooms, it is crucial to prioritize safety and responsible use. The mantra "start low, go slow" is often recommended, suggesting that individuals new to magic mushrooms should start with a low dose (typically considered 0.5 to 1 gram) and gradually increase the dosage over time. Additionally, it is advised to consume mushrooms in a comfortable, familiar, and safe setting, preferably with trusted companions or in the presence of a sober trip sitter.
While psilocybin mushrooms have been traditionally used for healing rituals and religious ceremonies, they have also gained attention for their therapeutic potential in recent years. Clinical trials and therapeutic use of psilocybin have employed fixed doses of 25 mg, consistent with previous weight-based dosing protocols. Microdosing, or consuming small amounts of psilocybin-containing mushrooms without experiencing mind-altering effects, is another emerging trend in therapeutic exploration. Regardless of the dosage or context of use, it is essential to approach psilocybin mushrooms with respect and caution, recognizing that individual experiences may vary significantly.
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A high dose of 3.5 grams of dried mushrooms
It is important to note that the psilocybin content between species and strains can range from 0.5–2% per gram. The average psilocybin content is around 1% psilocybin per one gram of dried Psilocybe cubensis mushroom. Therefore, a 3.5-gram dose of this species will likely contain 35 mg of psilocybin. However, there is intra- and inter-species variability in psilocybin content, and mushroom caps usually have higher psilocybin levels than mushroom stems.
When considering a high dose of psilocybin mushrooms, it is crucial to prioritize safety. Different species of psilocybin-containing magic mushrooms vary in strength and effects, and it is recommended to start with a low dose and gradually increase. The mantra for trying a new psychoactive drug is "start low, go slow." It is also important to obtain mushrooms from a trusted source and know the species you are consuming.
Additionally, your environment and state of mind play a significant role in the effects of psychedelic fungi. Choosing a comfortable, familiar, and safe setting can positively impact your experience. It is advised to avoid using magic mushrooms if you are in a negative or stressful mindset.
While the effects of psilocybin are not influenced by body weight, individual factors, such as the user's unique physiology and psychology, can impact the experience. It is recommended to start with a low dose of 0.1 to 1 gram and gradually increase to determine the optimal dosage for your transformative experience.
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A heroic dose of 5 grams of dried mushrooms
A “heroic dose”, as defined by Terence McKenna, refers to consuming over 5 grams of dried mushrooms, or roughly 50 mg of psilocybin. This is considered a huge dose and may result in a complete loss of the sense of self, or "ego dissolution" (also known as "ego death"), as well as the inability to think or make decisions. This level of cognitive impairment should not be taken lightly, and careful preparation and supervision are necessary to ensure safety.
The Psilocybe cubensis species of mushrooms typically contain around 0.5% to 1% psilocybin by weight, with some sources stating ranges of 0.1% to 2%. This equates to approximately 1% psilocybin per gram of dried mushrooms, or 50 mg of psilocybin in 5 grams of dried mushrooms. However, it is important to note that psilocybin content can vary between species and even within the same species, so it is recommended to start with a lower dose when using a new batch of mushrooms.
The effects of a heroic dose of psilocybin can include sensory and perceptual changes, synesthesia (such as hearing colours or tasting sounds), cognitive changes, and ego dissolution. It is important to note that the effects of psilocybin can vary between individuals, and factors such as environment and state of mind can also play a significant role in the overall experience. Therefore, it is recommended to consume psilocybin in a comfortable, familiar, and safe setting, and to avoid using magic mushrooms if one is in a negative or stressful mindset.
When considering a heroic dose of psilocybin, it is crucial to prioritize safety. It is recommended to start with smaller doses and gradually work up to higher doses to understand how magic mushrooms affect the individual. Additionally, it is advised not to mix magic mushrooms with other drugs, as this can increase the risk of a "bad trip". It is also important to ensure that the mushrooms are obtained from a trusted source and that the species is known, as potency can vary significantly between different species of mushrooms.
While the therapeutic use of psilocybin has gained interest in recent years, it is important to approach any consumption of psilocybin mushrooms with caution and to follow the mantra of "safety first". Understanding the correct dosage and potential effects is key to harm reduction when considering the use of magic mushrooms.
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Psilocybin content varies between species and strains
Psilocybe cubensis mushrooms typically contain between 0.5% and 1.0% of psilocin, which is the pharmacologically active metabolite of psilocybin. 0.7% of total psilocin equals about 1% of psilocybin. Therefore, a batch of Psilocybe cubensis mushrooms with a total psilocin content of 0.7% would be expected to contain approximately 1% psilocybin.
Different strains of Psilocybe cubensis mushrooms can vary in potency, with some strains, like the Enigma strain, known to be 1.5 to 2 times stronger than other cubensis strains. Additionally, mushroom caps typically have higher psilocybin levels than mushroom stems. For example, the Penis Envy strain, which is known to be particularly potent, may produce a significant psychedelic effect with a dose of only 0.5 to 1.0 grams of dried mushrooms.
The variability in psilocybin content between species and strains can have important implications for dosing and safety. A "heroic dose," as coined by Terrence McKenna, refers to a dose of over 5 grams of dried mushrooms (or approximately 50 mg of psilocybin). At this dose, individuals may experience a complete loss of their sense of self ("ego dissolution" or "ego death") and the ability to think or make decisions. Due to the potential for cognitive impairment, careful preparation and supervision are necessary for safety.
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Frequently asked questions
On average, there is around 1% psilocybin per 1 gram of dried Psilocybe cubensis mushrooms. This equates to 10mg of psilocybin per gram. However, psilocybin content varies between species and strains, ranging from 0.5% to 2% per gram.
A low dose of psilocybin is typically considered to be between 0.1 and 1 gram. At this level, you may experience a sense of euphoria and an enhancement of the senses, such as seeing more vibrant colours.
A high dose of psilocybin is typically considered to be 3.5 grams, which is likely to contain around 35mg of psilocybin. At this level, you will likely experience heavy perceptual and cognitive distortions and a full-blown psychedelic experience.
A "heroic dose", as coined by Terrence McKenna, is a dose of over 5 grams of dried mushrooms, or roughly 50mg of psilocybin. This massive dose may cause a complete loss of one's sense of self, also known as "ego dissolution" or "ego death", and the ability to think or make decisions.

























