John Miller
The dosage of mushrooms, or more specifically, psilocybin, is a topic of interest for those exploring the therapeutic benefits of this substance. Psilocybin is the main psychedelic ingredient in magic mushrooms, and its effects can vary depending on the dosage and individual factors. When it comes to dosage, a common starting point is 1 gram of dried mushrooms, which is considered a low dose and can induce noticeable effects without a complete break from reality. However, it's important to note that the psilocybin content in mushrooms can vary between species, typically ranging from 0.5% to 2% of dry weight. As a result, the same weight of different mushroom species may lead to different effects. Additionally, body weight can also be considered when determining dosage, with some studies suggesting a range of 0.28-0.43 mg/kg or 0.3-0.6 mg/kg. For those seeking a full-blown psychedelic experience, higher doses in the range of 20-30 mg of psilocybin are typically required. However, it is crucial to prioritize safety and gradually increase doses, starting with a low dose and slowly experimenting with higher amounts once comfortable.
| Characteristics | Values |
|---|---|
| Common low dose | 1 gram of dried mushrooms or 10 mg of psilocybin |
| Common high dose | 3.5 grams of dried mushrooms or 20-30 mg of psilocybin |
| Ultra-high dose | 5 grams of dried mushrooms or 50 mg of psilocybin |
| Microdose | 100 mg to 250 mg of dried mushrooms or 5-10% of a standard dose |
| Synthetic psilocybin dose in research studies | 2-4 mg |
| Fixed psilocybin dose in clinical trials | 25 mg |
| Supratherapeutic dose | 50-60 mg or 5-6 grams |
| Psilocybin dose based on weight | 0.3 mg/kg, 0.45 mg/kg, or 0.6 mg/kg |
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What You'll Learn
A low dose of 1 gram of magic mushrooms
Magic mushrooms contain the psychedelic compound psilocybin, which is metabolized by the body into psilocin, the active compound responsible for the psychedelic effects. The effects of psilocybin are influenced by its resemblance to serotonin, a neurotransmitter in the brain. The potency of magic mushrooms varies depending on the species, with some types producing stronger effects than others. Typically, there is about 1% psilocybin per 1 gram of dried Psilocybe cubensis mushrooms, which equates to approximately 10 milligrams of psilocybin in a 1-gram dose.
At this dosage, users often report experiencing euphoria and an enhancement of their senses, such as seeing more vibrant colours. Some may also feel a sense of spiritual connection and have deeper thoughts or new insights. However, it's important to note that the effects of magic mushrooms are not limited to positive experiences. Some individuals, especially those prone to anxiety, may encounter thought loops or find it challenging to shift their focus away from negative thoughts.
It is crucial to approach magic mushrooms with caution and to be well-informed about their effects and potential risks. Magic mushrooms are considered a Class A drug in most jurisdictions, and penalties for possession or supply can be severe. Additionally, the effects of magic mushrooms can be profound and may cause a shift in one's perception of the world. It is recommended to wait at least three months between taking magic mushrooms to allow for full processing and recovery from the experience.
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A medium dose of 1.75 grams of dried mushrooms
When discussing mushroom dosages, it is essential to distinguish between dried mushrooms and pure psilocybin. Psilocybin is the primary psychoactive ingredient in psychedelic mushrooms, and its concentration can vary between different species of mushrooms. Generally, dried Psilocybe cubensis mushrooms contain around 1% psilocybin by weight, so a 1.75-gram dose of these mushrooms would provide a similar amount of psilocybin as mentioned earlier.
It is worth noting that microdosing is a different concept, involving smaller amounts of psilocybin-containing mushrooms that do not induce mind-altering effects. Microdoses are typically in the range of 100 to 250 mg of dried mushrooms, taken intermittently over several days. This approach aims to provide subtle benefits, such as improved mood or energy, without the full psychedelic experience.
The effects of psilocybin are well studied, and it has gained attention for its potential therapeutic benefits. Research has shown that psilocybin carries a favorable safety profile compared to other psychedelics and classic drugs. While the primary concern is psychological safety, properly conducted studies and therapeutic settings aim to minimize potential psychological harm through patient preparation and monitoring.
It is important to emphasize that the information provided here is for informational purposes only. The use of psychedelic substances carries inherent risks, and individuals should always exercise caution and seek guidance from trusted sources when considering the use of substances like psilocybin mushrooms.
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A high dose of 20-30 mg of psilocybin
Psilocybin is the main psychedelic ingredient in psychedelic mushrooms. It is an indole alkaloid that occurs naturally in several species of fungi within the genus Psilocybe. These mushrooms are pan-tropical and can be found in the southeastern United States, Central and South America, Southeast Asia, and parts of Africa.
The optimum dose of psilocybin for positive and long-lasting effects with minimal risk of a bad trip is believed to be around 20 mg/70 kg. At this dosage, all volunteers in the Johns Hopkins study benefited from positive experiences, although with less intensity than at the highest dose.
It is important to note that the effects of psychedelic mushrooms are influenced by factors such as environment and state of mind. Additionally, the psilocybin content in dried mushrooms can vary between species, with mushroom caps generally containing higher levels than stems.
When it comes to therapeutic use, psilocybin has been studied for its potential in treating mental health conditions like treatment-resistant depression (TRD) and PTSD. Research has shown that psilocybin doses of 10 mg or 25 mg have no short-term or long-term detrimental effects on healthy individuals.
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A fixed psilocybin dose of 25 mg
The 25 mg dose of psilocybin is equivalent to approximately 2.5 grams of dried Psilocybe cubensis mushrooms. This is considered a standard dose, with higher doses of 3.5 grams (or an eighth of an ounce) likely to contain 35 mg of psilocybin. The effects of psilocybin are also influenced by individual factors such as body weight, with doses typically ranging from 0.2-0.4 mg/kg of psilocybin per session. However, one study found no significant differences in the psychedelic effects between the fixed 25 mg dose and weight-based doses of 0.29 mg/kg and 0.43 mg/kg.
The 25 mg dose of psilocybin has been shown to have a peak subjective effect at 60-90 minutes after administration, with an active duration of 4-6 hours. It is important to note that the effects of psilocybin can vary depending on the individual's environment and state of mind. While psilocybin has been found to be safe for use within controlled settings, it is important to closely monitor participants for any potential psychological harms or adverse events.
Psilocybin has gained attention for its therapeutic potential, particularly in the treatment of mental health conditions such as treatment-resistant depression (TRD) and PTSD. The 25 mg fixed dose has been utilised in clinical trials to explore the efficacy of psilocybin in these areas, with positive results and little-to-no safety concerns reported. This dosage provides a consistent and controlled approach to administering psilocybin, allowing for a better understanding of its effects and potential therapeutic benefits.
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A microdose of 100-250 mg of dried magic mushrooms
Microdosing involves taking small, non-perceptual amounts of psilocybin-containing mushrooms. This means that you won't experience any mind-altering effects, but you may feel subtle positive effects like a boost in mood or energy. A microdose is typically defined as 5-10% of a standard psychoactive dose, which for psilocybin is estimated to be between 0.1 and 0.3 grams (100 to 300 mg) of dried Psilocybe cubensis mushrooms.
It's important to remember that if you start to feel any psychedelic effects, your dosage is too high, and you should reduce it. Additionally, it's crucial to source your mushrooms from a trusted provider and be aware that the potency of magic mushrooms can vary by species.
While microdosing has gained popularity, there is still insufficient evidence to determine whether it is beneficial or safe in the long term. Most studies have focused on single doses, and the limited data available suggests that side effects, while mild and short-lived, can include increased blood pressure, anxiety, and enhanced cognitive functioning.
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Frequently asked questions
One gram of magic mushrooms is commonly considered a low dose that still produces noticeable effects. At 1% psilocybin content, this would be 10 milligrams (mg) of psilocybin.
2.0 grams of dried mushrooms contain 20 mg of psilocybin, which is considered a standard dose.
A high dose of psilocybin is considered to be 3.5 grams of dried mushrooms, which will have around 35 mg psilocybin content.
It is recommended to start with no more than one gram of dried mushrooms, or 10 mg of psilocybin. This is not a microdose, but a low, noticeable dose.
Current clinical trial protocols have switched to using a fixed psilocybin dose, most commonly 25 mg, which is considered safe and consistent with previous weight-based dosing.
