
It is possible to build a tolerance to magic mushrooms, also known as shrooms, which are wild or cultivated mushrooms that contain psilocybin, a naturally occurring psychoactive and
| Characteristics | Values |
|---|---|
| Tolerance dissipation time | A few days to two weeks |
| Tolerance calculator | Online tools available |
| Microdosing | Mixed results |
| Cross-tolerance | LSD and other serotonergic substances |
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What You'll Learn

Take breaks of several days between doses
Taking breaks of several days between doses is a strategy to reduce mushroom tolerance. Tolerance dissipates after a few days, so spacing doses a few days apart can help to avoid tolerance. For example, using mushrooms two days in a row can often lead to a diminished experience on the second day.
Taking breaks of several days between doses can help to reset the body's tolerance to mushrooms. This strategy is based on the understanding that tolerance to mushrooms is not long-lasting, and that trips can return to their peak intensity after a short break. The length of the break depends on individual factors, but it is generally recommended to discontinue use for at least a week to return to normal tolerance levels.
During the break, it is important to consider the potential risks associated with mushroom use. Mushrooms can induce adverse reactions such as nausea, panic attacks, and "bad trips". It is also important to be able to identify mushrooms, as some varieties are poisonous and can cause serious harm.
In addition to taking breaks, there are other strategies to manage mushroom tolerance. For example, some users may choose to microdose psilocybin, which involves taking a tiny dose of psilocybin several times a week for several weeks. However, the effectiveness of microdosing has shown mixed results.
Another strategy is to use a mushroom tolerance calculator, which can help determine an appropriate dose based on the user's last dose amount, desired amount, and the number of days since the last consumption. These calculators take into account the tolerance that may have been built up over time.
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Avoid cross-tolerance with LSD and other substances
Psilocybin, the naturally occurring psychedelic compound in magic mushrooms, interacts with serotonin receptors in a similar way to LSD. This means that taking LSD can produce a tolerance to psilocybin, even if you haven't consumed magic mushrooms at the same time. This is known as cross-tolerance.
Cross-tolerance can also develop between psilocybin and phenethylamines such as mescaline and DOM. This is because psilocybin, LSD, and phenethylamines are all serotonergic substances, which activate serotonin receptors.
To avoid cross-tolerance with LSD and other substances, it is recommended to leave a period of at least two weeks between consuming these substances and psilocybin mushrooms. This will allow your tolerance level to return to its base level.
It is important to note that the development of tolerance can occur quickly with regular use of magic mushrooms. This means that, over time, you may need to consume larger amounts of mushrooms to achieve the same effects. However, consuming a large amount of mushrooms can result in an overdose, which can cause non-fatal symptoms such as tachycardia, hypertension, hyperthermia, nausea, and vomiting. Therefore, it is important to be aware of your tolerance level and adjust your dosage accordingly.
There are mushroom tolerance calculators available online that can help you determine a suitable dosage based on your last dose amount, desired amount, and the number of days since your last consumption. These calculators take into account the tolerance you may have built up over time. Additionally, spacing doses several days apart can help avoid the effects of tolerance.
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Use a mushroom tolerance calculator
Tolerance to mushrooms refers to the body's reduced response to the effects of psilocybin, the active compound in magic mushrooms. While mushroom use is not physically addictive, tolerance can develop with repeated use, leading to a diminished experience.
A mushroom tolerance calculator is a tool that can help you estimate your current tolerance level and provide guidance on dosing and timing to minimise the development of tolerance. Here's how you can use one:
- Find a Reliable Mushroom Tolerance Calculator: Search for a well-reviewed and trusted mushroom tolerance calculator online or on mobile app stores. For example, a simple search may lead you to the "Magic Mushroom Calculator" app.
- Input Your Information: Tolerance calculators typically require information such as your weight, the type of mushroom you're using, and the frequency of your mushroom use. Be as accurate as possible when providing this information.
- Calculate Your Tolerance: Using the information you've provided, the calculator will estimate your current tolerance level. It may provide a percentage or a more qualitative description, such as "low," "moderate," or "high" tolerance.
- Follow the Recommendations: Based on your tolerance level, the calculator may suggest specific dosing guidelines, including the amount and timing of your doses to minimise further tolerance buildup. These recommendations are designed to help you maintain a balanced approach to mushroom consumption.
- Regularly Re-evaluate Your Tolerance: Tolerance to mushrooms can fluctuate over time, especially if you adjust your dosing or take breaks from using mushrooms. Tolerance dissipates after a few days, so spacing out your doses is essential to minimising tolerance buildup and maintaining the desired effects of psilocybin.
By using a mushroom tolerance calculator, you can make more informed decisions about your mushroom usage. Remember that tolerance dissipation takes a few days, so spacing out your doses is essential to minimising tolerance buildup and maintaining the desired effects.
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Microdose psilocybin
Microdosing psilocybin involves taking a fraction of a regular dose, or a sub-perceptual dose, that is much lower than one would take to experience a "trip" or hallucination. A microdose is typically defined as 5-10% of a standard psychoactive dose, which for psilocybin is generally estimated to be between 0.1 and 0.3 grams (100 to 300 mg) of dried Psilocybe cubensis mushrooms. However, due to the inherent variability in the potency of mushrooms, it is challenging to achieve a precise and consistent sub-perceptual dose outside of a controlled, clinical environment.
The practice of microdosing psilocybin has gained popularity in recent years, with many people reporting benefits such as enhanced mood, creativity, concentration, productivity, and ability to empathize with others. Some studies have found small to medium-sized improvements in mood and mental health, while others have shown little to no benefit. The lack of standardized definitions and placebo-controlled studies complicates attempts to perform consistent research on the effects of microdosing psilocybin.
Psilocybin is generally thought to be safe in low dosages, and it does not lead to physical dependence. However, it is important to note that psilocybin can cause adverse reactions such as nausea and panic attacks, and if one takes too large of a dose, it can result in a terrifying or even traumatic experience.
When considering microdosing with psilocybin, it is crucial to source the mushrooms from a trusted provider to ensure their accuracy and safety. Additionally, starting with a very low dose and exercising caution, especially for those new to the practice, is essential due to the variability in potency.
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Discontinue use for a week to reset tolerance
Tolerance to magic mushrooms is very real, and it can develop quickly with regular use. This means that, with continued use, a person will need to consume more of the drug to achieve the same effect. This can be especially risky with mushrooms because consuming a large amount can result in an overdose.
However, tolerance to magic mushrooms is not long-lasting, and a short reset period can bring trips back to their peak intensity. One way to reset tolerance is to discontinue use for a week or so. This will return people to their normal tolerance level.
It is important to note that the effects of magic mushrooms are highly variable and influenced by factors such as dosage, age, weight, personality, emotional state, environment, and history of mental illness. Therefore, when discontinuing use to reset tolerance, it is essential to consider these factors and plan accordingly.
During the week of discontinuing use, it is advisable to focus on self-care and creating a comfortable environment. This can include engaging in relaxing activities, spending time in nature, and connecting with supportive friends or community members. It is also important to be mindful of potential withdrawal symptoms and seek professional support if needed.
By taking this break from using magic mushrooms, individuals can effectively reset their tolerance and prepare for future trips with enhanced effects.
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Frequently asked questions
Mushroom tolerance is not long-lasting and typically dissipates after a few days.
To reduce mushroom tolerance, it is recommended to space doses several days apart. Alternatively, discontinuing use for about a week will return people to their normal tolerance level.
Yes, mushroom tolerance calculators are available online. These tools allow you to estimate a suitable dose by entering your last dose amount, your desired amount, and the number of days since your last consumption.

























