
Yawning is a common side effect of consuming magic mushrooms, and it is often regarded as a notable part of the psychedelic experience. While the exact cause of this phenomenon remains unknown, there are several theories that attempt to explain it. One theory suggests that yawning is related to serotonin receptors in the brain, specifically the 5-HT2A and 5-HT2C subtypes. Psilocin, the active compound in magic mushrooms, binds to these receptors and elicits psychedelic effects. Another theory posits that mushrooms influence how the brain perceives and reacts to oxygen levels, leading to increased yawning as a way to regulate oxygen intake. Despite the lack of a definitive explanation, the yawning side effect is generally not a cause for concern and can even be seen as a positive indicator of the mushrooms' potency.
| Characteristics | Values |
|---|---|
| Nutritional content | Rich in B vitamins, vitamin D, selenium, potassium, and copper |
| Neurotransmitter activity | May influence serotonin and dopamine levels, leading to increased yawning |
| Oxygen levels | May affect how the brain perceives oxygen levels, triggering a yawning response |
| Relaxation | May contain compounds that promote relaxation and reduce fatigue |
| Social bonding | Yawning as a response to seeing others yawn, potentially facilitating social bonding |
| Hallucinogenic properties | Certain mushrooms contain psilocybin and psilocin, causing hallucinations similar to LSD |
| Health risks | Poisonous mushrooms can cause severe gastrointestinal issues and, in rare cases, death |
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What You'll Learn

Yawning is a common side effect of taking mushrooms
Mushrooms influence neurotransmitter activity and oxygen levels in the body, which contributes to yawning. They contain compounds that interact with neurotransmitters like serotonin and dopamine, essential for mood regulation. The rich nutritional content of mushrooms, particularly B vitamins, boosts serotonin production. As your brain adjusts to the increased serotonin, it can lead to more frequent yawning. Additionally, mushrooms may impact how your brain perceives oxygen levels, triggering yawning as a natural respiratory response when oxygen levels are perceived to be low.
The calming compounds found in certain mushrooms also promote relaxation, which can further contribute to yawning. Yawning itself is a fascinating physiological process that helps regulate body temperature and increase alertness. It often occurs when you're feeling fatigued, as a signal that your body needs a boost of oxygen and to combat tiredness.
The chemical composition of different mushroom varieties varies, resulting in diverse effects on the body and mind. Some mushrooms may enhance alertness, while others promote calmness or induce mystical experiences. Understanding the complex interactions between these chemical compounds and neurotransmitters provides insight into the intriguing mechanisms through which mushrooms influence brain function and human behavior.
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The serotonin 5-HT2C receptor may play a role in causing yawns
Yawning is a common occurrence in humans and animals, often associated with stretching and sleepiness. While the exact physiological function of yawning remains unknown, research has revealed that it is regulated by various neurotransmitters and neuropeptides in the brain. One neurotransmitter that has been implicated in yawn induction is serotonin, also known as 5-HT.
5-HT was first proposed to be involved in yawn regulation by Urba-Holmgren et al., who observed that treatment with a selective 5-HT reuptake inhibitor, citalopram, enhanced physostigmine-induced yawning. This effect was blocked by the 5-HT receptor antagonist, metergoline. While the mechanism of 5-HT's role in yawning was initially unclear, subsequent studies have provided more insights.
Recent studies have suggested that 5-HT likely plays multiple roles in mediating yawning. Specifically, the activation of 5-HT2C receptors has been linked to the induction of yawning. This was demonstrated by dose-dependent increases in yawning observed after the administration of 5-HT2C-preferring agonists such as m-CPP, TFMPP, and MK 212. These effects were blocked by 5-HT2 receptor antagonists like mianserin and ritanserin. Additionally, unlike with other types of agonist-induced yawning, 5-HT2C agonist-induced yawning is not reduced by D2-like antagonists or oxytocin antagonists.
The involvement of the 5-HT2C receptor in yawn induction is further supported by studies on the serotonergic modulation of yawning. These studies have shown that while depletion of endogenous 5-HT enhances D2-like agonist- and physostigmine-induced yawning, increasing serotonergic activity through treatment with 5-hydroxytryptophan inhibits yawning. Furthermore, the activation of 5-HT2C receptors results in yawn induction through a mechanism unrelated to oxytocin neurotransmission in the paraventricular nucleus (PVN). However, it is important to note that the specific brain region(s) responsible for serotonergic yawn induction are yet to be identified.
In summary, the serotonin 5-HT2C receptor appears to play a significant role in causing yawns. The activation of these receptors induces yawning, and this effect is mediated through specific neural pathways and interactions with other neurotransmitters. While the exact mechanism requires further elucidation, the current understanding highlights the complex and multifaceted nature of yawn regulation in the body.
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Yawning is a mechanism to regulate brain temperature
Yawning is a fascinating physiological process that activates several mechanisms in the brain and body. One of the primary functions of yawning is to regulate brain temperature and maintain optimal temperature levels for cognitive processes.
When an individual yawns, they initiate a series of physiological responses aimed at cooling down the brain. This regulatory mechanism becomes particularly important when the brain experiences an increase in temperature, often associated with heightened mental activity and cognitive load. By triggering a yawn, the body facilitates a temporary decrease in brain temperature, providing a refreshing effect and enhancing cognitive performance.
Mushrooms, particularly certain varieties, contain compounds that interact with the neurotransmitters in the brain. These compounds can influence the balance of neurotransmitters like serotonin and dopamine, which are crucial for mood regulation and cognitive functions. Serotonin, for example, plays a vital role in maintaining alertness and regulating sleep-wake cycles. By affecting serotonin production and activity, mushrooms can indirectly impact brain temperature regulation.
Additionally, mushrooms are known to possess calming properties, promoting relaxation and reducing stress levels. This calming effect can lead to a decrease in brain activity, which in turn helps regulate brain temperature. The nutritional content of mushrooms, specifically their high vitamin B content, further contributes to this process. Vitamin B supports energy metabolism and can influence the body's ability to maintain optimal temperature levels, including brain temperature.
While the exact mechanisms are still being explored, the link between mushroom consumption and yawning provides intriguing insights into the complex nature of yawning and its role in maintaining brain health and optimal cognitive function.
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Yawning is contagious, and some are more susceptible
Yawning is a fascinating physiological process that involves several mechanisms in the brain and body. It is a natural respiratory response when the body is low on oxygen, helping to regulate temperature and increase alertness. Interestingly, yawning is also contagious, and understanding this phenomenon provides insight into the complex nature of human social behaviour.
When you see someone yawn, you might find yourself yawning in response. This behaviour suggests that yawning serves as a form of non-verbal communication between individuals. It indicates a level of empathy and social bonding, revealing an intriguing aspect of human interaction.
Mushrooms, particularly certain varieties, are known to induce yawning due to their influence on neurotransmitter activity and oxygen levels in the body. The nutritional content of mushrooms, specifically B vitamins, boosts serotonin production, which can lead to increased yawning as the brain adjusts. Additionally, the calming compounds found in some mushrooms promote relaxation, further contributing to yawn-inducing effects.
The impact of mushrooms on brain activity can result in various psychological effects, including enhanced alertness, creativity, and mood regulation. The chemical composition of different mushroom varieties leads to distinct effects on neurotransmitter activity. Some mushrooms, often referred to as "magic mushrooms," contain substances like psilocybin and psilocin, which can induce hallucinations and are considered illegal drugs.
It is important to note that the effects of mushrooms vary depending on the specific type and dosage. While some mushrooms promote relaxation and improved cognitive abilities, others can have more intense effects, including anxiety, paranoia, and distorted senses of time, place, and reality. In rare cases, consuming extremely large amounts of certain mushrooms can even lead to severe health consequences or death. Therefore, it is crucial to approach the consumption of mushrooms with caution and be aware of their potential impacts on the body and mind.
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Remedies include lemon tek, breathing through the nose, and cold compresses
Lemon tek is a method of preparing mushrooms with something acidic, such as lemon or lime juice, before consumption. It is believed to pre-metabolize the psilocybin present in the mushrooms into psilocin, though this claim is not supported by scientific literature. People who use lemon tek say that the psychedelic effects are stronger and the onset of the trip is quicker, with the duration being shorter.
Breathing through the nose is beneficial as it increases oxygen intake, reduces exposure to foreign substances, and helps your body effectively use the air you inhale. Nasal hair filters out dust, allergens, and pollen, preventing them from entering your lungs. The nose also warms and moisturizes the air you breathe in, making it easier for your lungs. Additionally, nitric oxide is produced during nasal breathing, which helps to widen blood vessels.
Breathing exercises can help improve nose breathing and enhance lung function, increase respiratory muscle strength, and relieve stress and anxiety. Alternate nostril breathing is a common exercise where you inhale through one nostril and exhale through the other while using your finger to close the opposite nostril.
Cold compresses, such as ice packs or damp towels, can be used to reduce pain, swelling, and inflammation. They numb the affected area and should not be used for the first 48 hours after an injury.
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Frequently asked questions
There is currently no scientific consensus on why yawning occurs after ingesting magic mushrooms. However, it is a common side effect, and some people even look forward to it as a sign that the mushrooms are working.
If yawning is disrupting your experience, you could try reducing your dosage. Some fans of the Lemon Tek method—which involves infusing ground or chopped mushrooms in lemon juice—claim that it helps reduce yawning.
Yawning is considered a side effect of magic mushrooms because it is not typically caused by other factors like sleepiness or boredom. However, it's important to note that yawning is a normal and usually benign reflex, and there are many potential causes.
Anecdotal evidence suggests a link between dosage and the amount of yawning. This may be due to the chemical variability between batches of mushrooms or the physical health and metabolism of the user.

























