
Mushrooms are fungi, a separate kingdom from plants or animals. They contain a variety of chemical compounds, including nutrients such as chitin, cellulose, starch, and glucose. Some mushrooms also contain psychoactive chemicals, such as psilocybin, which is converted to psilocin in the body and has hallucinogenic effects. Psilocybin is the key ingredient in magic mushrooms and has a long history of use in traditional ceremonies. It is also being studied for its potential therapeutic effects on mental health conditions. Mushrooms can be analysed through chemical experiments and tests to identify their compounds and determine their safety for consumption.
| Characteristics | Values |
|---|---|
| Kingdom | Fungi |
| Eukaryotic | Yes |
| Heterotrophic | Yes |
| Cellulose | Present in cell walls |
| Chitin | Present in cell walls |
| Starch | Absent |
| Glucose | Almost completely absent |
| High levels of | Cadmium, Mercury, Radiocaesium isotopes |
| Sources of | Ergosterol, Provitamin D₂, Phenolids |
| Contains | Pyrrole Alkaloid |
| Main compounds | Psilocybin, Psilocin |
| Converted to | Psilocin in the body |
| Receptors | Serotonin 5-hydroxytryptamine 2A (5HT2a) receptor |
| Effects | Euphoria, Hallucinations, Distorted sense of time, Fear, Panic |
| Use | Traditional ceremonies, Recreational, Therapeutic |
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What You'll Learn

Magic mushrooms and their chemical composition
Mushrooms are fungi, a distinct kingdom of eukaryotic organisms that are neither plants nor animals. Like plants, they absorb nutrients from their surroundings by osmosis, but they do not photosynthesize. Instead, they require food to survive, like animals.
Magic mushrooms, or psilocybin mushrooms, are a type of hallucinogenic mushroom and a polyphyletic informal group of fungi that contain the prodrug psilocybin. Psilocybin is a naturally occurring psychedelic found in certain types of mushrooms that grow on nearly every continent. The psilocybin content of mushrooms varies from almost nothing to 2.5% of their dry weight, depending on species, strain, growth and drying conditions, and mushroom size. The most potent species are members of the genus Psilocybe, such as P. azurescens, P. semilanceata, and P. cyanescens. However, psilocybin has also been isolated from over a dozen other genera, including Panaeolus, Inocybe, and Pluteus.
When ingested, psilocybin is converted by the body into psilocin, which is chemically related to the neurotransmitter serotonin and acts as a non-selective agonist of the serotonin receptors. Activation of the serotonin 5-HT2A receptor is specifically responsible for the hallucinogenic effects of psilocin and other serotonergic psychedelics. The experience, or "trip," is strongly dependent on the user's state of mind, previous encounters with psychedelic drugs, and expectations, as well as the environment in which the drug is taken. Perceptual changes, such as visual and auditory hallucinations, an inability to discern fantasy from reality, panic reactions, and psychosis may occur, particularly with large doses.
Other compounds that may be present in magic mushrooms include norpsilocin, baeocystin, norbaeocystin, and aeruginascin, which can modify the effects of psilocybin. Certain mushrooms also produce β-carbolines, such as harmine, harmane, tetrahydroharmine (THH), and harmaline, which inhibit monoamine oxidase (MAO), an enzyme that breaks down tryptamine alkaloids.
The use of magic mushrooms rarely results in life-threatening symptoms, and it is difficult to overdose on them. However, misidentifying mushrooms and consuming a toxic variety is a risk, as some poisonous mushrooms resemble magic mushrooms. Additionally, combining magic mushrooms with certain medications or other drugs can be dangerous.
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Mushrooms as a food source
Mushrooms are a type of fungus, biologically distinct from plant- and animal-derived foods. They are neither plants nor animals, but form their own taxonomic kingdom. Like plants, mushrooms absorb organic nutrients from their surroundings by osmosis, but their structure and way of reproducing are quite different from plants. Like animals, mushrooms are heterotrophic, meaning they need to take in food and cannot make it themselves.
Mushrooms have been eaten and used as medicine for thousands of years. They are low in calories and fat, and contain modest amounts of fiber, protein, and various nutrients, including vitamins, minerals, and antioxidants. They are also a good source of potassium, which can help to reduce blood pressure. Mushrooms are recognized by chefs for their ability to create savory, rich flavors called umami, thanks to the presence of the amino acid glutamate.
Mushroom production is consistent with a sustainable food supply. They are a local or regional food source, and most mushroom farms are family-owned. Mushroom farms recycle byproducts from other agricultural sectors, providing a useful solution for waste management. The substrate material on which mushrooms are grown can be recycled as a soil amendment. Growing mushrooms indoors also allows producers to better control environmental factors, land use, and energy and water needs.
It is important to note that not all mushrooms are edible. Many wild mushrooms are poisonous and can be hard to distinguish from edible varieties, so it is recommended to source mushrooms from markets rather than foraging them from the wild unless one is trained in recognizing wild mushrooms.
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The health benefits of mushrooms
Mushrooms are a fungus, and they are a popular addition to meals in the United States, with the average American consuming approximately three pounds of mushrooms annually. They are a good source of flavour and nutrition without adding too much fat, calories, sodium or cholesterol to one's diet.
Research has shown that mushrooms have many health benefits. They are a powerful source of ergothioneine, an amino acid and antioxidant that prevents or slows cellular damage. A review of 17 cancer studies from 1966 to 2020 showed that eating just 18 grams of mushrooms daily may lower one's risk of cancer by as much as 45%. Mushrooms also contain polysaccharides, their most abundant carbohydrate, which stimulates the growth of healthy bacteria in the gut.
Mushrooms are a natural source of vitamin D, which is essential for maintaining and building strong bones, as well as boosting immune function and reducing inflammation. They are also a good source of vitamin B6, which helps the body form red blood cells, proteins and DNA. Additionally, mushrooms are low in sodium, which can help keep blood pressure in check.
Shiitake mushrooms, in particular, are known to help keep cholesterol levels low. They contain compounds that inhibit the production and absorption of cholesterol, while also lowering overall cholesterol levels in the blood.
In a study in Singapore, participants who ate more than two cups of mushrooms a week had a 50% lower risk of developing Mild Cognitive Impairment (MCI). Even those who ate only one cup saw some benefit.
While the health benefits of mushrooms are significant, it is important to note that certain types of mushrooms, known as "magic mushrooms", contain psilocybin, a psychoactive chemical. These mushrooms are used recreationally or to improve mental health, and can cause hallucinations and shifts in perception. However, they may also have potential therapeutic uses for conditions such as depression, PTSD, addiction, pain, and neurodegenerative disorders.
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The risks of consuming mushrooms
Mushrooms are fungi, a separate kingdom from plants or animals. They are heterotrophic, meaning they need to take in food as they cannot make it themselves.
Some mushrooms contain the drug psilocybin, also known as magic mushrooms or shrooms. When psilocybin is ingested, it is converted by the body into psilocin, the chemical with psychoactive properties. Psilocybin binds to and activates serotonin receptors in parts of the brain such as the prefrontal cortex and amygdala, which affect mood, cognition, and perception.
While psilocybin has been used for thousands of years in religious rituals and traditional ceremonies, and there is ongoing research into its potential to treat conditions such as depression, post-traumatic stress disorder (PTSD), addiction, pain, and neurodegenerative disorders, there are several risks associated with consuming mushrooms.
Poisonous Mushrooms
The main risk of consuming mushrooms is the possibility of misting a poisonous mushroom for one that contains psilocybin. Poisonous mushrooms can look very similar to those with hallucinogenic properties, and consuming them can be fatal. Symptoms of mushroom poisoning include muscle spasms, confusion, and delirium, and require immediate medical attention.
Bad Trips
The effects of psilocybin vary from person to person and can be influenced by factors such as mental health, setting, quantity, and expectations. In some cases, individuals may experience a "bad trip", characterized by extreme fear, anxiety, panic, paranoia, or psychosis. The risk of a bad trip can be reduced by being in a good state of mind, with trusted friends, and in a safe environment before taking psilocybin.
Polydrug Use
Combining psilocybin with other drugs, including over-the-counter or prescribed medications, can lead to unpredictable and dangerous effects. For individuals taking psychiatric medications, psilocybin may cause a relapse or worsening of their condition.
Physical Effects
While psilocybin is not considered physically addictive, regular users may develop a tolerance to its effects. Additionally, unpleasant physical effects such as increased heart rate, nausea, and delayed headaches may occur after consuming psilocybin.
In conclusion, while mushrooms have been used traditionally and show potential for medicinal use, consuming them, especially without proper identification and preparation, can pose serious health risks. It is important to be cautious and informed about the potential dangers associated with mushroom consumption.
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Mushrooms as a chemical system in education
Mushrooms are a fascinating subject of study, and their chemical composition is a topic that can be explored in great depth within the field of education. They have a long history of use in traditional ceremonies and have more recently become a subject of interest in the scientific community for their potential medicinal properties.
In terms of their chemical composition, mushrooms contain a variety of substances, including proteins, carbohydrates, fats, vitamins, and minerals. They are a good source of ergosterol, provitamin D2, and phenolids, which have antioxidative properties. Additionally, mushrooms contain high levels of potassium and other trace elements, depending on the substrate on which they grow.
When it comes to education, mushrooms can be a valuable tool for teaching students about chemistry and its applications in daily life. Simple experiments can be designed to help students identify important compounds and nutrients present in mushrooms. For example, students can learn about the presence of chitin and cellulose in the cell walls of fungi, which is a unique structural feature not found in plants or animals. Furthermore, the study of mushrooms can dispel the common misconception that "chemical-free" food is desirable. By understanding that all food is composed of chemical substances, students can gain a more accurate perspective on the role of chemistry in their everyday lives.
In addition to their chemical composition, mushrooms also have a significant impact on human health, particularly in the areas of mental and nutritional well-being. The presence of psilocybin, a naturally occurring tryptamine alkaloid, in certain types of mushrooms has led to their classification as magic mushrooms. Psilocybin is converted by the body into psilocin, which is responsible for the psychoactive properties associated with these mushrooms. While the use of magic mushrooms can induce perceptual changes, such as hallucinations and a distorted sense of time and space, it is important to note that they can also have adverse effects, including extreme fear, anxiety, and paranoia, known as a "bad trip." Therefore, the educational study of mushrooms should also encompass their potential risks and dangers, particularly when consumed alongside other substances or medications.
Overall, mushrooms serve as an excellent example of how chemistry is inherently intertwined with our natural world. By studying mushrooms as a chemical system, students can gain a deeper understanding of the role of chemistry in their daily lives and develop a more informed perspective on the potential benefits and risks associated with different substances.
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Frequently asked questions
A chemical system is any system that involves chemical reactions or interactions. This can include anything from a simple chemical equation to complex biological processes.
Yes, mushrooms are a type of fungus. They are not plants or animals but form their own kingdom. They absorb nutrients from their surroundings like plants, but their structure and reproduction are different.
Mushrooms contain a variety of chemical compounds, including chitin and cellulose in their cell walls, and health-promoting compounds like β-glucans, ergosterol, provitamin D₂, and antioxidants. Some mushrooms also contain psychoactive chemicals like psilocybin and psilocin.
Psilocybin, or 4-phosphoryloxy-N,N-dimethyltryptamine (4-PO-DMT), is a naturally occurring tryptamine alkaloid found in over 200 species of mushrooms. It has hallucinogenic and serotonergic effects, causing changes in perception, euphoria, and spiritual experiences. Psilocybin is converted by the body into psilocin, which is chemically related to serotonin.
Magic mushrooms, or psilocybin mushrooms, cause shifts in perception and can induce hallucinations, a distorted sense of time and space, and intense emotions. They have been used in traditional ceremonies and are now being studied for their potential therapeutic effects on conditions like depression, PTSD, and addiction.





















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