
Mushrooms, like all living organisms, undergo mutations. These mutations can occur in the wild and can be caused by various factors, such as environmental conditions or DNA errors. While most mutations are harmless, they can sometimes lead to new strains with unique characteristics. In the wild, mushrooms that grow in fairy rings have been found to accumulate surprisingly few mutations over time, indicating a well-developed protection mechanism against harmful mutations. These findings have significant implications for medicine and evolutionary biology, as understanding how mushrooms resist mutations can provide insights into ageing and disease prevention.
| Characteristics | Values |
|---|---|
| Mutation speed | Low |
| Mutation accumulation over time | Low |
| Protection against harmful mutations | High |
| Types of mutations | Abnormal formations, discolourations, blob, coral, dino egg shapes, giant mushrooms |
| Mutation causes | DNA errors, changes in DNA, cell division |
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What You'll Learn
- Mushrooms that grow in 'fairy rings' accumulate fewer mutations
- Mutations can impact a mushroom's appearance, growth speed, and resistance to contaminants
- Mutations can be harmful, causing weird growths and impacting reproductive capacity
- Long-lived mushrooms are more vulnerable to harmful mutations
- Mutations can be caused by changes in DNA

Mushrooms that grow in 'fairy rings' accumulate fewer mutations
Mushrooms are a type of fungus that grows in fairy rings, also known as "scotch bonnets," and they are called so because they often grow in circular patterns. These mushrooms have a long lifespan, and every cell in them contains DNA, which dictates the functions that the cell can perform.
Whenever a cell divides, there is a risk of new mutations occurring. These mutations can cause a loss of cell function and increase the risk of diseases such as cancer. Therefore, it is crucial to maintain the integrity of the DNA over time. While mutations are common in long-lived organisms, it has been found that mushrooms that grow in fairy rings accumulate surprisingly few mutations.
In a study published in the journal Current Biology, researchers from Uppsala University investigated the mutation rate in the long-lived mushroom species Marasmius oreades, often found in fairy rings. They used whole-genome DNA sequencing to examine the speed and pattern of mutations. The results showed that the number of mutations per cell division was surprisingly low, given the expected number of cell divisions.
The mechanism behind this protection against harmful mutations is not yet fully understood. However, researchers suggest that extremely effective DNA repair systems or asymmetric DNA division during cell division may play a role. This discovery has implications for both medicine and evolutionary biology, and it could potentially provide new insights into understanding and preventing diseases like cancer.
Overall, the findings suggest that mushrooms that grow in fairy rings have evolved mechanisms to maintain high genome integrity and protect themselves against harmful mutations, even over extended periods of growth.
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Mutations can impact a mushroom's appearance, growth speed, and resistance to contaminants
Mushrooms can mutate in the wild, and these mutations can have a range of impacts on their appearance, growth speed, and resistance to contaminants.
Appearance
Mutations in mushrooms can lead to abnormal formations and discolourations. They can affect the mushroom's colour, shape, size, and cap, resulting in odd and sometimes eerie forms. For example, the Albino Penis Envy mutant has a unique appearance due to its lack of the typical cap and stem structure. Blob mutations, also known as Dino Eggs, are common in certain strains and lead to solid, unusual shapes. Coral mutations can also occur, causing the mushroom mycelium to grow outward into branching structures resembling coral reefs.
Growth Speed
Mutations can impact the speed at which mushrooms grow. Some mutations may stunt the development of mushrooms, leading to slower growth rates. Slow-growing mushroom strains are more prone to contamination as they require more time for bulk colonisation and fruiting. For example, mutated strains of Cubensis, such as B+ or Penis Envy, can take 3-6 weeks to reach the first flush, while other Cubensis strains typically take only 3-4 weeks.
Resistance to Contaminants
Mutations can also affect a mushroom's ability to resist contaminants. In some cases, mushrooms may develop mutations that help them fight contamination, leading to unique growth patterns. However, mutations can also make mushrooms more susceptible to contamination, especially if they hinder spore production or development. For example, blob mutations that stop developing halfway through can be challenging to harvest and may be at higher risk of contamination.
While mutations can have negative consequences, they also provide opportunities for growers to cultivate new strains with unique qualities. By understanding and selecting specific mutations, growers can develop mushrooms with desirable characteristics, such as improved resistance to contaminants or unique appearances.
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Mutations can be harmful, causing weird growths and impacting reproductive capacity
Mushrooms, like all living creatures, are susceptible to harmful mutations. Changes in DNA, or mutations, can cause a loss of cell function, boosting the risk of disease. Whenever a cell divides, there is an increased risk of new mutations, and long-lived organisms are particularly vulnerable as every cell can contribute DNA to the next generation.
Some mushroom mutations are somatic, meaning they occur in the mycelium during the mushroom life cycle, but not in the spores. These mutations don't always get passed on, and they can create unique traits within specific sections of a colony. For example, a patch of albino mushrooms might stand out among their ordinary beige-brown relatives in the same cluster. Other mutations just happen spontaneously as a natural part of the mushroom life cycle, caused by minor errors in DNA replication or environmental stressors like UV light radiation, extreme temperature changes, or viruses.
Mushroom mutations can cause weird growths, stunt development, or make it difficult for mushrooms to produce viable spores, impacting their reproductive capacity. Most mutations affect the mushroom's appearance, resulting in changes in colour, shape, size, or strange growths on the caps. For example, UV exposure has been shown to cause unique, resilient mutants, but at the expense of natural mushroom reproduction, leading to sterility. Blob and coral mutations are also common and can reduce overall yield and reproductive capacity since they don't produce spores.
Long-lived mushrooms that grow in 'fairy rings' accumulate surprisingly few mutations over time, indicating that they have well-developed protection against harmful mutations. In-depth studies of these fungi can provide important knowledge about the challenges that need to be resolved for individuals to grow old and reproduce at an advanced age.
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Long-lived mushrooms are more vulnerable to harmful mutations
Mushrooms, like all fungi, are susceptible to mutations. Mutations are changes in the DNA of a cell, which can cause a loss of cell function and increase the risk of disease. Whenever a cell divides, there is a risk of new mutations occurring. Therefore, long-lived organisms, where each cell can contribute DNA to the next generation, are particularly vulnerable to harmful mutations.
A study published in the journal Current Biology examined the mutation speed in the long-lived mushroom species Marasmius oreades, often found in "fairy rings". Fairy rings are naturally occurring circular growth patterns found on lawns or in woodlands and forests. Researchers from Uppsala University used whole-genome DNA sequencing to study the emergence and accumulation of mutations in this species over many years.
The results of the study showed that the number of mutations per cell division was surprisingly low, indicating that long-lived mushrooms have well-developed protection against harmful mutations. This finding is significant in terms of both medicine and evolutionary biology. While the mechanism facilitating this protection is currently unknown, researchers suggest that extremely effective DNA repair systems or asymmetric DNA division during cell division may play a role.
In summary, while long-lived mushrooms are theoretically more vulnerable to harmful mutations due to their longevity, the Marasmius oreades species exhibits a surprisingly low mutation rate. This suggests that long-lived mushrooms may have evolved robust mechanisms to protect against harmful mutations, providing valuable insights for future drug development and our understanding of evolutionary biology.
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Mutations can be caused by changes in DNA
Mutations are changes in a DNA sequence. They can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses. Mutations can also occur when a mutagen reacts with the parent DNA, causing a structural change that affects the base-pairing capability of the altered nucleotide.
All living creatures have cells that contain DNA, which encodes the functions that the cell can perform. Changes in DNA can cause mutations that may lead to a loss of cell function, increasing the risk of disease. For example, a mutation in a key gene may cause the cell to die if the protein coded by the mutant gene is defective. Enzymes can repair a variety of genetic mutations before they affect how a cell functions, but it is still important for the DNA to be kept intact over time.
In the case of mushrooms, researchers from Uppsala University investigated the mutation speed in the long-lived mushroom species Marasmius oreades, which often grows in "fairy rings". The results showed that the number of mutations per cell division was surprisingly low, indicating that these mushrooms have a well-developed protection mechanism against harmful mutations. The mechanism facilitating this protection is currently unknown but may involve extremely effective DNA repair systems or asymmetric DNA division during cell division.
Organisms that are long-lived and in which every cell can contribute DNA to the next generation are particularly vulnerable to harmful mutations. This is because, over time, errors in the DNA accumulate due to mutations. As a result, long-lived organisms are at an increased risk of developing diseases caused by mutations, such as cancer. However, not all genetic mutations lead to genetic disorders, and some mutations may even have positive effects on humans.
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Frequently asked questions
Mushrooms in the wild do mutate. Mutations can cause changes in colour, shape, size, and strange growths on the caps. These mutations may be harmless, but they can also affect the mushroom's development and ability to produce spores, reducing yield and reproductive capacity.
Mutations occur when there are errors in the DNA of a mushroom's cells. These errors can arise from various factors, such as environmental conditions or during cell division, where the risk of new mutations increases.
While most mutations may be detrimental, some can lead to the development of new strains with unique characteristics. For example, certain mutations can result in larger mushrooms, which can be beneficial for yield. Additionally, mutations can change a mushroom's resistance to contaminants and its potency, creating new opportunities for medicinal or psychoactive species.

























