
While some mushrooms are toxic and can cause acute kidney injury and renal failure, others can be beneficial for kidney health. Shiitake mushrooms, for example, are a good source of plant-based protein and are lower in potassium, sodium, and phosphorus than other varieties. They are recommended for individuals with kidney disease, especially those following a plant-based or renal diet. However, it is important to exercise caution when consuming wild mushrooms, as they can cause poisonings that lead to renal failure and increased creatinine levels. Therefore, it is always advisable to consult a medical professional before making any dietary changes, especially when dealing with kidney problems.
| Characteristics | Values |
|---|---|
| Mushroom species causing acute renal failure | Amanita phalloides, Cortinarius orellanus, Boletus edulis |
| Symptoms of mushroom poisoning | Vomiting, diarrhoea, abdominal pain, severe hepatic failure, kidney failure |
| Treatment for mushroom poisoning | Intravenous hydration, insulin, glucose, N-acetyl-cysteine, silymarin, penicillin G sodium, activated charcoal, water and electrolyte replacement, pyridoxine, vitamin K, traxenamic acid, fresh plasma |
| Mushroom species safe for kidney disease patients | Shiitake, white button, portobellos |
| Nutritional benefits of mushrooms | B vitamins, copper, manganese, selenium, plant-based protein, dietary fibre, vitamin D, potassium |
| Negative effects of mushrooms | High levels of oxalates, which can lead to kidney stones |
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What You'll Learn
- Certain mushrooms can cause acute kidney failure and elevated creatinine levels
- Shiitake mushrooms are a good source of plant-based protein for people with kidney issues
- Mushroom poisoning can lead to acute renal failure and increased creatinine levels
- Mushroom coffee may be beneficial for kidney health, but its effects are not scientifically proven
- Wild mushrooms can cause poisonings, resulting in elevated creatinine levels and renal failure

Certain mushrooms can cause acute kidney failure and elevated creatinine levels
Mushroom poisoning can lead to acute kidney injury and renal failure, as evidenced by several case studies. Poisoning by certain mushroom species, such as Amanita phalloides and Cortinarius orellanus, can cause elevated creatinine levels and severe renal deterioration. In one case, a patient presented with intractable vomiting and diarrhoea 12-15 hours after mushroom ingestion, with creatinine levels of 3.4 mg/dL. Treatment for mushroom poisoning involves supportive and symptomatic care, and in some cases, haemodialysis and plasmapheresis for toxin removal.
Mushroom poisoning can result in a mixed syndrome of hepatic and renal failure, as seen in a case study of a 74-year-old male patient. The patient exhibited vomiting, diarrhoea, and elevated creatinine levels after consuming mushrooms from the species Amanita phalloides and Cortinarius orellanus. The patient was treated with penicillin G sodium, activated charcoal, water and electrolyte replacement, and other supportive measures.
Amanita phalloides is a well-known cause of mushroom poisoning, leading to acute renal failure and elevated creatinine levels. In one instance, a patient's creatinine levels rose to 4.2 mg/dL, and they were admitted to the intensive care unit. Another case study reported a maximum creatinine level of 7.1 mg/dL in a patient who remained asymptomatic, and their kidney function gradually improved.
While wild mushrooms can cause poisonings, certain mushroom species are beneficial for individuals with kidney issues. Shiitake mushrooms, for instance, are recommended as a plant-based meat substitute for those on a renal diet due to their lower potassium content. They are also a good source of B vitamins, copper, manganese, selenium, and plant-based protein. However, it is always advisable to consume mushrooms in moderation, paying attention to portion sizes.
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Shiitake mushrooms are a good source of plant-based protein for people with kidney issues
While mushrooms have been linked to acute renal failure and kidney injury in cases of mushroom poisoning, certain types of mushrooms are recommended as part of a kidney-friendly diet.
Shiitake mushrooms, in particular, are recommended as a food option for people with kidney issues. They are a good source of plant-based protein and are lower in potassium, sodium, and phosphorus than other types of mushrooms. This is beneficial for people with kidney problems as they need to watch their potassium intake.
Shiitake mushrooms are also an excellent source of B vitamins, copper, manganese, and selenium. They contain many of the same amino acids as meat and are thus a good substitute for meat. They are also a good source of dietary fiber.
In addition, shiitake mushrooms are the only natural plant source of vitamin D, which is important for building strong bones. They also have antimicrobial properties and may help fight cancer, boost immunity, and support heart health.
It is important to note that nutritional needs and restrictions change during the course of kidney disease, so it is recommended to speak with a doctor or registered dietitian before making any dietary changes.
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Mushroom poisoning can lead to acute renal failure and increased creatinine levels
Mushroom poisoning is a significant cause of concern, especially during the autumn season when wild mushroom harvesting is prevalent. Poisoning from certain mushroom species, such as Amanita phalloides and Cortinarius orellanus, can lead to serious health issues, including acute renal failure and increased creatinine levels.
Amanita phalloides, also known as the "Death Cap," is a highly toxic mushroom species responsible for numerous cases of mushroom poisoning. The toxins in this mushroom cause severe hepatic and renal failure, with patients presenting symptoms such as intractable vomiting, diarrhoea, and abdominal pain. The toxins affect cells with high metabolism, including hepatocytes and the cells of the proximal tubules of the kidneys, leading to cell death and organ failure.
Cortinarius orellanus is another poisonous mushroom species that can cause orellanine syndrome, a mixed syndrome of hepatic and renal failure. Patients may experience symptoms similar to those of Amanita phalloides poisoning, including vomiting and diarrhoea, but the onset of symptoms may vary, with some cases occurring within 6 hours of ingestion and others taking longer.
The treatment for mushroom poisoning is primarily supportive and symptomatic. Intravenous hydration, including saline solution and sodium bicarbonate, is often administered, along with insulin and glucose to normalise kalemia. N-acetyl-cysteine is also used to treat mushroom poisoning, and in some cases, haemodialysis may be required if renal recovery is absent or delayed.
It is important to note that not all mushrooms are harmful, and some mushrooms, like shiitake mushrooms, are recommended for individuals with kidney disease. Shiitake mushrooms are lower in potassium, sodium, and phosphorus and are a good source of plant-based protein and dietary fibre. They also contain B vitamins, copper, manganese, and selenium, making them a nutritious option for those with renal health concerns.
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Mushroom coffee may be beneficial for kidney health, but its effects are not scientifically proven
While mushroom coffee has gained popularity, it is important to understand the effects of its consumption, especially for those with kidney health concerns. Marketers of mushroom coffee claim that it offers numerous health benefits, but it is essential to separate marketing from scientific evidence.
Firstly, it is important to note that mushroom coffee typically contains both ground mushrooms and ground coffee beans, so it is still a caffeinated beverage. However, the reduction in caffeine content compared to regular coffee may be beneficial for those looking to lower their caffeine intake, as it can reduce jitters and improve sleep quality.
Secondly, while some mushrooms have been used in traditional medicine and contain various nutrients, the process of drying, extracting, and brewing mushrooms may impact the health benefits. For example, certain mushrooms used in mushroom coffee, like the chaga variety, contain high levels of oxalates. Consuming too many oxalates can increase the risk of developing kidney stones. Additionally, there is some evidence that the extracts in mushroom coffee can be difficult to digest, and those with kidney issues may be more vulnerable to these effects.
Lastly, while specific types of mushrooms, like shiitake mushrooms, are recommended for individuals with kidney disease due to their low potassium content, it is always advisable to consult a doctor or dietitian before making dietary changes. They can provide personalized recommendations based on your specific kidney health needs.
In conclusion, while mushroom coffee may offer some potential benefits for kidney health, such as reduced caffeine intake and the inclusion of certain nutrients, it is important to approach the claimed benefits with a degree of skepticism until more scientific studies are conducted. Consulting a healthcare professional is crucial before incorporating any new dietary trends, especially when managing kidney health.
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Wild mushrooms can cause poisonings, resulting in elevated creatinine levels and renal failure
The clinical presentation of mushroom poisoning typically begins 6 to 12 hours after ingestion. The initial phase includes cholera-like symptoms such as diarrhoea, vomiting, and abdominal pain. However, after a brief period of clinical improvement, the condition deteriorates, leading to the second phase, which involves severe hepatic failure and kidney failure. This is due to the presence of toxins like amatoxin, which inhibits RNA polymerase II, resulting in cell death, particularly in cells with a high metabolism, including kidney cells.
Creatinine levels can surge significantly in cases of mushroom poisoning, as evidenced by reported cases. For instance, one patient's creatinine levels rose to 10.6 mg/dL, necessitating hemodialysis due to severe renal deterioration. In another case, a patient's creatinine levels increased to 4.2 mg/dL, compared to a previous value of 1.5 mg/dL. These elevated creatinine levels are indicative of impaired kidney function and highlight the seriousness of mushroom poisoning.
It is worth noting that mushroom poisoning can be classified into two main groups based on the time elapsed from ingestion to the onset of symptoms. If symptoms appear within 6 hours of ingestion, it falls into one category, while a longer duration places it in the other. Treatment for mushroom poisoning should be supportive and symptomatic, and early intervention, within 5 days of poisoning, is crucial for effective toxin removal. Intravenous hydration, including saline solution and sodium bicarbonate, is often administered, along with specific treatments tailored to the patient's needs.
While wild mushrooms can indeed cause poisonings that result in elevated creatinine levels and renal failure, it is important to differentiate between wild and cultivated mushrooms commonly found in grocery stores or markets. Shiitake mushrooms, for example, are recommended as a plant-based protein option for individuals with kidney issues. They are lower in potassium, sodium, and phosphorus than other varieties, making them a suitable choice for those with renal disease. Additionally, mushrooms, in general, are a good source of B vitamins, copper, manganese, selenium, and dietary fiber. However, it is always advisable to consult a doctor or dietitian to determine the best dietary choices for kidney health, as individual needs may vary.
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Frequently asked questions
Yes, mushrooms can be a part of a kidney-friendly diet, but only in moderation. Shiitake mushrooms, in particular, are a good source of plant-based protein and are lower in potassium, sodium, and phosphorus than other varieties.
No, some mushrooms are poisonous and can cause acute renal failure. Poisonous mushrooms include Amanita phalloides and Cortinarius orellanus.
The first stage of mushroom poisoning includes cholera-like diarrhea, vomiting, and abdominal pain. After a period of clinical improvement, cytolytic hepatitis occurs silently. The third phase begins 48 hours or more after ingestion, with severe hepatic failure and kidney failure.
Treatment for mushroom poisoning is supportive and symptomatic. Intravenous hydration, insulin, glucose, and N-acetyl-cysteine are often administered.
There is limited scientific evidence to support the health claims of mushroom coffee. However, it does contain beneficial ingredients from medicinal mushrooms and has half the caffeine of regular coffee.

























