
Active Hexose Correlated Compound (AHCC) is a proprietary extract derived from the mycelia of shiitake (Lentinus edodes) mushrooms. It is a group of chemicals taken from fungi and turned into a supplement to boost the immune system. AHCC has been studied for its role in the immune system, cancer, liver disease, and Human Papillomavirus (HPV). It has been investigated for various applications in more than 100 scientific publications.
| Characteristics | Values |
|---|---|
| Full form | Active Hexose Correlated Compound |
| Type | Supplement |
| Source | Shiitake mushrooms |
| Benefits | Boosts immunity, anti-inflammatory, anticancer effects, enhanced resistance to microbial infections, may protect against oxidative stress-induced disorders, may improve prognosis and prevent recurrence of hepatocellular carcinoma, may help clear HPV infections |
| Side effects | May cause hypersensitivity reactions, not recommended during pregnancy or breastfeeding |
| Dosage | 1 to 3 grams daily |
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What You'll Learn

AHCC is a supplement made from mushrooms
AHCC, or Active Hexose Correlated Compound, is a supplement made from mushrooms. It is a proprietary extract derived from the mycelia of shiitake (Lentinus edodes) mushrooms. It is rich in alpha-1,4-glucan oligosaccharides, which are thought to enhance its biological effects.
The supplement has been studied for its potential benefits to the immune system, as well as its role in cancer, liver disease, and Human Papillomavirus (HPV) treatment. It has been suggested that AHCC may help the immune system fight HPV infection, which can lead to cervical cancer. In addition, AHCC has been shown to improve T-cell immune responses, increase dendritic cell number and function, and improve antibody response to the influenza vaccine.
AHCC is available in capsule form and is marketed as a natural immunity booster. It is said to maintain natural killer cell activity and has been the focus of research at various prestigious institutions worldwide, including over 30 human clinical studies. However, it is important to note that AHCC is not intended to treat, cure, or prevent any disease, and individuals should always speak with a healthcare provider before taking any supplement.
The recommended dosage of AHCC may vary depending on its purpose, with daily doses typically ranging from 1 to 3 grams. It is manufactured in Japan and includes ingredients made in Japan, while the supplements are produced in the USA in an FDA-registered facility.
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It is used to boost the immune system
Active Hexose Correlated Compound (AHCC) is a group of chemicals derived from the mycelia of shiitake (Lentinus edodes) mushrooms. It is rich in alpha-1,4-glucan oligosaccharides, which are thought to enhance its biological effects.
AHCC is used to boost the immune system. It works by enhancing cytokine production, maintaining T-cell and natural killer cell activity and longevity, increasing the number of dendritic cells, and promoting optimal T cells and macrophage activity. In healthy adults, AHCC improved T-cell immune responses, increased dendritic cell number and function, and improved antibody response to the influenza vaccine.
AHCC has been studied for its role in regulating the immune system, with promising results in small trials. For example, a small trial of 36 adults showed that AHCC effectively boosted the immune system after four weeks. Another small study of 41 females found that AHCC suppressed HPV infections after three to six months.
However, it is important to note that there is a lack of extensive clinical research on AHCC, and it is not regulated in the same way as prescription drugs. As such, it is recommended to consult a healthcare professional before taking AHCC or any other supplement, as they can interact with medications and may not be suitable for individuals with certain allergies or conditions.
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AHCC may help fight infections and diseases
Active Hexose Correlated Compound (AHCC) is a group of chemicals derived from the mycelia of shiitake mushrooms. It is available in the form of supplements and is known to improve the immune system.
AHCC has been studied for its efficacy in treating various bacterial and viral infectious diseases. It has been found to improve resistance to bacterial infections by increasing inflammatory cytokine and chemokine expression as well as lymphocytes. In a study, immunosuppressed mice inoculated with Methicillin-resistant Staphylococcus aureus (MRSA) showed significantly extended survival duration when administered AHCC.
AHCC has also been found to improve resistance to viral infections. It has been studied for its efficacy in treating the influenza virus, West Nile virus, hepatitis virus, and human papillomavirus (HPV) infection. In a randomized, double-blind, placebo-controlled study, about 60% of patients infected with high-risk HPV showed resolution of the infection after AHCC intake for 6 months. AHCC supplementation also increased T-cell counts, indicating that it may eliminate HPV by modulating immunity.
Additionally, AHCC has been found to improve T-cell immune responses and increase resistance to fungal infections. It has been studied for its efficacy in treating Candida albicans infection.
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It is available in capsules and powder form
Active Hexose Correlated Compound (AHCC) is a proprietary extract derived from the mycelia of shiitake (Lentinus edodes) mushrooms. It is available in capsules and powder form. The capsules are typically made from vegetable products and are suitable for vegans. The powder can be added to drinks and food, or it can be encapsulated at home.
The capsules are available in various strengths, from 500mg to 1100mg per capsule, and are often sold in packs of 60 or 90 capsules. The powder is also available in different quantities, from small bags to bulk buys.
AHCC is a natural supplement that is designed to support immune health. It is suitable for men and women and is often marketed as a way to maintain overall wellness. It is not intended to treat, cure, or prevent any disease, and users should always consult a healthcare professional before taking any supplement.
The recommended dosage of AHCC may vary depending on the purpose of its use. Daily doses are typically between 1 and 3 grams. It is important to read the ingredients list and nutrition facts panel to know which ingredients are included and in what quantities.
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AHCC may have side effects and interactions
AHCC (Active Hexose Correlated Compound) is a proprietary blend derived from the mycelia of several species of cultivated mushrooms. The mushrooms used are typically hybridized derivatives of Basidiomycetes fungi, including the species Lentinus dorsalis and Lentinus edodes (shiitake). AHCC has been studied for its potential immune-boosting and health-promoting effects, and it is often marketed as a dietary supplement. While AHCC is generally considered safe for most people, as with any supplement, there may be side effects and potential interactions with medications or other supplements.
Possible side effects of AHCC are typically mild and may include digestive issues such as nausea, diarrhea, and stomach discomfort. These side effects are generally more likely to occur when AHCC is consumed in high doses or by individuals with sensitive stomachs. Additionally, as AH CC stimulates the immune system, there is a potential risk of autoimmune reactions being triggered or existing autoimmune conditions being exacerbated. Individuals with autoimmune diseases or those taking immunosuppressant medications should use AHCC with caution and under medical supervision.
Furthermore, AHCC may interact with certain medications. For example, because AHCC may lower blood sugar levels, individuals taking diabetes medications should monitor their blood sugar closely and consult their healthcare provider to avoid potential hypoglycemia. AHCC may also interact with blood-thinning medications, such as warfarin, as it could potentially enhance the blood-thinning effect and increase the risk of bleeding. Additionally, AHCC might interfere with chemotherapy drugs, as its immune-boosting effects could potentially reduce the drugs' effectiveness.
Individuals taking any prescription medications or other supplements should consult their healthcare provider before taking AHCC to ensure safe and appropriate use. This is especially important for individuals with existing medical conditions or those who are pregnant or breastfeeding, as the potential risks and benefits should be carefully considered. While AHCC is generally well-tolerated, understanding its potential side effects and interactions is crucial for ensuring safe and effective use.
To minimize the risk of side effects, it is recommended to start with a lower dose of AHCC and gradually increase it while monitoring for any adverse reactions. Additionally, purchasing AHCC from reputable sources and following the recommended dosage instructions on the product label or as advised by a healthcare professional can help ensure safety and efficacy. Overall, while AHCC has shown promising results in various studies, more comprehensive clinical research is needed to fully understand its effects, particularly regarding long-term use and specific populations.
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Frequently asked questions
AHCC stands for Active Hexose Correlated Compound (AHCC). It is a proprietary extract derived from the mycelia of shiitake mushrooms.
AHCC is used as a supplement to boost the immune system. It has also been studied for its role in cancer, liver disease, and Human papillomavirus (HPV).
AHCC works by enhancing cytokine production, maintaining T-cell and natural killer cell activity, increasing dendritic cells, and promoting optimal T cells and macrophage activity.
AHCC may interact with certain medications, such as cancer treatments and aromatase inhibitors. It is also not recommended for those with mushroom allergies or during pregnancy and breastfeeding due to a lack of available data. As with any supplement, it is important to consult a healthcare professional before use.

























