
There are thousands of mushroom species, and many of them are edible and have purported health benefits. Some of the most common types of mushrooms used in supplements include Lion's Mane, Chaga, Reishi, Cordyceps, Turkey Tail, Tremella, and Agaricus. The purported benefits of mushroom extracts range from anti-aging to immune support, cancer-fighting properties, and improved brain function. However, it's important to note that the effectiveness of mushroom extracts depends on the extraction process, and not all mushroom extracts on the market are created equal. The best extraction methods involve heat, such as hot water extraction, which releases the active compounds in mushrooms.
| Characteristics | Values |
|---|---|
| Types of mushroom extracts | Lion's Mane, Siberian Chaga, Reishi, Cordyceps, Agaricus, Tremella, Coriolus versicolor, Ganoderma lucidum, Turkey Tail |
| Extraction methods | Heat-based hot water, dual extraction, ineffective extraction, powder |
| Benefits | Anti-inflammatory, anti-aging, immune-boosting, cancer-fighting, improved cognition, anxiety reduction, wound healing, fatigue reduction, improved digestion |
| Risks | May not be well tolerated by individuals with mushroom allergies, may cause stomach discomfort, nausea and dizziness if taken above the recommended amount |
| Forms | Capsules, powders, liquid extracts, mouth sprays, teas, coffees, gummies |
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What You'll Learn
- Lion's Mane extract may improve brain function and support neurogenesis
- Chaga and Reishi extracts require a dual extraction with ethanol to unlock their active compounds
- Siberian Chaga extract is tested for beta-D-glucans, which are researched for immune system support
- Turkey Tail mushroom extract may boost immune function by increasing natural killer cells
- Mushroom extract supplements may help reduce anxiety and depression

Lion's Mane extract may improve brain function and support neurogenesis
Lion's Mane mushrooms have been used in traditional medicine in Asian countries for centuries. However, scientific research on the effects of Lion's Mane extract on the brain is still in its infancy.
Some studies have found that Lion's Mane extract may improve brain function and support neurogenesis. For example, a pre-clinical trial conducted by researchers from the University of Queensland found that Lion's Mane extract improved brain cell growth and memory in mice. The study also found that the active compounds in Lion's Mane extract promote neuron projections, extending and connecting to other neurons. This suggests that Lion's Mane extract may have a positive impact on neurogenesis.
Additionally, a small 2010 study found that menopausal women who consumed Lion's Mane mushrooms daily for one month reported reduced feelings of irritation and anxiety. This may be due to the potential anti-inflammatory effects of Lion's Mane extract, as inflammation is believed to be a major contributing factor to anxiety and depression.
While these initial findings are promising, more research is needed to confirm the effects of Lion's Mane extract on brain function and neurogenesis in humans. The majority of studies conducted so far have been on animals or in test tubes, and the sample sizes have been relatively small. Further investigation with larger sample sizes and more human studies is necessary to fully understand the potential benefits of Lion's Mane extract for brain health.
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Chaga and Reishi extracts require a dual extraction with ethanol to unlock their active compounds
Chaga and Reishi mushrooms are known for their antioxidant and immune-supporting properties, respectively. They have super-thick cell walls, which makes them challenging to break down and extract their beneficial compounds. This is where dual extraction with ethanol comes into play.
Dual extraction is a process that combines both water and ethanol as solvents to release a "full spectrum" of compounds from the mushrooms. Ethanol, also known as alcohol, plays a crucial role in extracting water-insoluble compounds, such as betulinic acid, betulin, and phytosterols, which are abundant in Chaga mushrooms. On the other hand, hot water extraction is the traditional method and is effective in releasing water-soluble compounds like beta-glucans and polyphenolic components.
The dual extraction process typically involves an initial hot water extraction step, where the mushrooms are simmered in water for an extended period. This breaks down the tough cell walls and extracts water-soluble compounds. The mixture is then strained, and the liquid is preserved. The second step introduces ethanol, which further extracts the alcohol-soluble compounds. This dual approach ensures that a broader range of beneficial compounds are released, making the extraction more comprehensive and potent.
For Chaga mushrooms, 190-proof ethanol is recommended as the most effective solvent for creating tinctures. It is the only edible solvent capable of effectively extracting the non-water-soluble compounds unique to Chaga. Additionally, the ethanol step in dual extraction can help isolate specific bioactive compounds in Chaga, such as triterpenes, sterols, and inotodiol, which have significant health benefits.
Reishi mushrooms, on the other hand, contain water-insoluble triterpenes like ganoderic acids, which contribute to the mushroom's bitter flavor. A dual extraction with ethanol ensures that these important compounds are not left out, providing a more complete and effective Reishi extract. The combination of hot water and ethanol extraction methods offers the benefits of both approaches, maximizing the therapeutic potential of these mushrooms.
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Siberian Chaga extract is tested for beta-D-glucans, which are researched for immune system support
Chaga mushroom is a highly beneficial substance for human health. It is known to increase immune function, boost brain activity, provide stable energy, and reduce stress. Chaga is the most studied herb globally, and its benefits are renowned.
Siberian Chaga extract is one of the most potent forms of Chaga, as it is wild-harvested from Birch trees. It is also known as the "'mushroom part' of the Chaga organism, which has been revered for its health benefits for thousands of years.
The Chaga extract is tested for beta-D-glucans, which are some of the most highly researched natural compounds for immune system support. Beta-glucans are the active constituents in Chaga that give it its amazing benefits. The beta-glucans in Siberian Chaga extract are easily dissolved in water, shakes, or smoothies.
The recommended dosage for adults is two capsules of organic Chaga extract per day, which can be taken at any time. For the best results, it is recommended to use the product over an extended period to notice the effects.
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Turkey Tail mushroom extract may boost immune function by increasing natural killer cells
Mushrooms have been used for their medicinal properties since at least 3000 BCE. They are reported to have antimicrobial, anti-inflammatory, cardiovascular-protective, antidiabetic, hepatoprotective, and anticancer properties. The Turkey Tail mushroom, in particular, has been found to have immune-boosting effects.
Research has shown that Turkey Tail mushroom extract can inhibit the growth and spread of certain types of cancer cells, such as human colon cancer cells. A clinical trial conducted in 2012 found that breast cancer patients who took capsules of powdered Turkey Tail mushroom recovered immune function after radiation therapy more quickly than those who didn't take the capsules. Another study found that Turkey Tail mushroom extract improved the efficacy of chemotherapy in breast cancer patients.
In addition to its anticancer properties, Turkey Tail mushroom extract has also been found to have antibacterial qualities. A test-tube study showed that the extract inhibited the growth of Staphylococcus aureus and Salmonella enterica, bacteria that can cause illness and infection. Turkey Tail mushroom extract may also help to improve athletic performance and reduce markers of fatigue, as seen in a mouse study.
Turkey Tail mushroom extract is generally well-tolerated and has been found to be immunomodulatory, especially at higher doses. It can be taken as a supplement in capsule form or used topically, as in the case of a vaginal gel for treating Human Papillomavirus (HPV) infections. Overall, Turkey Tail mushroom extract shows promise as a natural way to boost immune function and improve health.
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Mushroom extract supplements may help reduce anxiety and depression
Mushrooms have been used for medicinal purposes for thousands of years. Many types of mushrooms contain unique compounds that offer a wide range of health benefits, including the potential to help with anxiety and depression.
Reishi, also known as the "Mushroom of Immortality," has been used in Chinese medicine for over 2,000 years. It has been shown to have a positive impact on the immune system, which is important for mental health as a weakened immune system is linked to depression and anxiety. Reishi also contains compounds called triterpenoids, which have been shown to have anti-inflammatory, antioxidant, and anti-anxiety effects. In addition, Reishi contains beta-glucans, which are thought to have a positive impact on the immune system and enhance mood and sleep quality.
Lion's Mane is another type of edible mushroom that has been used for medicinal purposes for hundreds of years. It has gained popularity due to its unique properties, including the ability to support brain health and improve cognitive function. Lion's Mane contains compounds called hericystin and erinacines, which are thought to stimulate the growth of nerve cells and improve communication between these cells. Research has shown that anxiety and depression are associated with changes in brain structure and function, making Lion's Mane a promising natural treatment option.
Turkey Tail is a type of mushroom commonly used in traditional medicine to support the immune system. It contains a compound called PSK, which has been found to have anti-inflammatory and antioxidant effects. Turkey Tail has been shown to improve symptoms of anxiety and depression in some studies, likely due to its ability to affect neurotransmitter levels, which play a key role in regulating mood and anxiety.
Chaga mushroom is also rich in antioxidants and is known for its ability to support the immune system and reduce stress, which can help alleviate anxiety.
While the research on mushroom extract supplements for anxiety and depression is promising, it is important to note that the evidence is still evolving, and more studies are needed to fully understand their effectiveness and any potential risks. It is always recommended to consult with a healthcare professional before starting any new supplement regimen, especially when dealing with mental health concerns.
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Frequently asked questions
Mushroom extracts are supplements or powders produced from various types of mushrooms.
The mushrooms are first hand-sorted, ground to a coarse powder, and then combined with hot water. The liquid is then filtered, separating the solids from the liquid. The liquid is then concentrated into a powder.
Medicinal mushrooms have been credited with at least 130 therapeutic applications. Some benefits include anti-aging, improved cognition, immune support, anti-inflammatory effects, and cancer-fighting properties.
Yes, Lion's Mane, Siberian Chaga, Turkey Tail, Tremella, and Reishi mushrooms are all used for their purported health benefits.
Mushroom extracts can be found in capsules, powders, liquid extracts, mouth sprays, teas, coffees, gummies, and sometimes in combination with other products such as CBD.

























