
Mushrooms are widely consumed as a healthy food worldwide, but some people are allergic to them. The overall extent of mushroom allergies is not known, but it is thought to be rare. However, it can be life-threatening for those affected. Mushroom allergy symptoms can appear within minutes to hours after consuming mushrooms, and can include gastrointestinal issues, inflammation of the intestines, anaphylaxis, and even death. If you experience any symptoms after consuming mushrooms, it is important to seek medical attention immediately.
| Characteristics | Values |
|---|---|
| Prevalence of mushroom allergy | 1% to 10-30% of the allergic population |
| Cause of mushroom allergy | Body's immune system response to the proteins in mushrooms |
| Symptoms | Mild to severe anaphylaxis, gastrointestinal symptoms, inflammation of the intestines, influx of histamine, dilation of blood vessels, increased mucus production, constriction of the lungs, hives, itching, rash, drop in blood pressure, difficulty breathing, loss of consciousness |
| Treatment | Avoidance of mushrooms, antihistamines, vitamin C, aloe vera, epinephrine, allergy shots |
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What You'll Learn

Mild symptoms and home remedies
Some people do exhibit allergic reactions to mushrooms, and the symptoms can vary from mild to severe. Mild symptoms may include:
- Skin irritation, such as a rash, hives, or itching
- Redness and swelling of the skin
- Nausea, vomiting, or diarrhea
- Abdominal cramps
- Headache
- Runny nose or congestion
- Watery or itchy eyes
If you are experiencing any of these mild symptoms after consuming mushrooms, there are several home remedies that may help alleviate the discomfort:
- Remove any traces of mushrooms from your environment and wash your hands thoroughly to avoid further contact with the allergen.
- Take an over-the-counter antihistamine to help reduce itching, swelling, and hives.
- Apply a cold compress to the affected area to soothe itching and reduce swelling.
- Use calamine lotion or a similar over-the-counter product to relieve itching and dryness.
- Wear loose, cotton clothing to avoid irritating the skin further.
- Stay well hydrated by drinking plenty of fluids, especially if you are experiencing diarrhea or vomiting.
- Get plenty of rests to help your body recover and reduce the strain on your immune system.
For mild digestive symptoms, such as nausea, vomiting, or diarrhea:
- Sip clear fluids or electrolytes in small but frequent quantities to prevent dehydration.
- Once the vomiting or diarrhea has stopped, slowly introduce bland, easy-to-digest foods like crackers, rice, toast, and bananas.
- Avoid spicy, fatty, or greasy foods that can irritate your stomach further.
- Probiotics may also help restore balance to your digestive system.
It is important to note that these remedies are intended for mild allergic reactions to mushrooms. If you are experiencing severe symptoms, such as difficulty breathing, a rapid heartbeat, dizziness, or anaphylaxis, seek immediate medical attention. Additionally, always consult a healthcare professional if your symptoms persist or worsen, or if you are unsure about the severity of your reaction.
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Anaphylaxis and adrenaline
Mushroom allergies are uncommon but can be serious. The overall extent of mushroom allergies is not known, but it is estimated that it may affect 1% of people. However, it could be as prevalent as pollen and mould allergies, which affect 10-30% of an allergic population.
Mushroom allergies are triggered when the body's immune system overreacts to the proteins or moulds present in mushrooms. This causes an influx of histamine in the body, a hormone that helps protect against infections and diseases. Histamine causes blood vessels to dilate, increasing blood flow, mucus production, and can cause the lungs to constrict.
Mushroom allergy symptoms can range from mild to severe and can be life-threatening in some cases. Common symptoms include hives, skin rash, itching, swelling of the lips, tongue, throat, or face, difficulty breathing, stomach pain, and gastrointestinal issues. In severe cases, anaphylaxis can occur, which is a severe allergic reaction that can cause a rapid pulse, dizziness, a drop in blood pressure, difficulty breathing, and loss of consciousness.
If an individual experiences symptoms of anaphylaxis, it is considered a medical emergency, and epinephrine (also known as adrenaline) should be administered immediately. Adrenaline comes in pre-loaded adrenaline auto-injectors (AAIs) that are designed to be easy to use. It is important for individuals at risk of anaphylaxis to carry these injectors with them at all times and know how and when to use them.
In addition to adrenaline, other treatments for mushroom allergies include antihistamines and corticosteroids. Antihistamines can help alleviate mild symptoms such as a runny nose, itching, and sneezing. Corticosteroids may be prescribed for severe symptoms to reduce inflammation. Allergen immunotherapy, or allergy shots, is another treatment option that involves injecting small doses of the allergen into the body to build up immunity over time.
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Mushroom allergy diagnosis
Another method of diagnosis is a blood test, which measures the amount of specific antibodies, known as Immunoglobulin E (IgE), in the blood. If the IgE levels are high, it indicates an allergic reaction. However, results from blood tests may take a few days, unlike the immediate results from skin prick tests.
It is important to note that the overall extent of mushroom allergies is not precisely known. It may be very slight, with only 1% of people experiencing allergic reactions to eating mushrooms. However, it could also be as prevalent as pollen and mould allergies, affecting 10-30% of an allergic population.
If an individual suspects they have a mushroom allergy, they should consult a healthcare professional, such as an allergist, for diagnosis and treatment. The most effective treatment for a mushroom allergy is to avoid mushrooms altogether, including common types such as shiitake, portobello, white button, and oyster mushrooms. Antihistamines can help relieve mild allergy symptoms, but severe anaphylactic reactions require immediate medical attention and treatment with epinephrine.
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Species of mushrooms and their effects
People can indeed be allergic to mushrooms, and this is influenced by the specific species of mushroom and individual sensitivity. Mushrooms, belonging to the fungi kingdom, encompass a diverse range with varying effects on human health. Some species are safe and nutritious, offering potential medicinal benefits, while others can induce allergic reactions or even pose serious health risks. Here is an overview of some common mushroom species and their respective effects:
Button Mushrooms (Agaricus bisporus): This popular variety, including white and brown mushrooms, is generally well-tolerated and considered safe for most individuals. They are a good source of nutrients, providing selenium, riboflavin, niacin, and ergothioneine, an antioxidant with potential health benefits. However, some people may exhibit allergic reactions, ranging from mild symptoms like itching and hives to more severe anaphylactic responses.
Shiitake Mushrooms (Lentinula edodes): Native to East Asia, shiitake mushrooms are widely cultivated and valued for their culinary and potential medicinal properties. They contain compounds like eritadenine and beta-glucans, which may offer immune-boosting and cholesterol-lowering effects. However, shiitake mushrooms can also trigger allergies, particularly in individuals sensitive to mold or with pre-existing respiratory conditions. Allergic reactions can manifest as respiratory issues, skin rashes, or gastrointestinal discomfort.
Oyster Mushrooms (Pleurotus ostreatus): Oyster mushrooms are known for their delicate flavor and texture and are commonly used in cuisine and traditional medicine. They contain unique polysaccharides and sterols, which may provide anti-inflammatory and antioxidant benefits. While generally considered safe, some individuals may experience allergic reactions, particularly those with pre-existing allergies to other types of fungi. Allergic symptoms can include nasal congestion, skin irritation, and, in rare cases, anaphylaxis.
Chanterelle Mushrooms (Cantharellus cibarius): Chanterelle mushrooms are wild mushrooms prized for their distinct flavor and aroma. They are a rich source of vitamins and minerals, including vitamins C and D, potassium, and iron. Chanterelle mushrooms are generally well-tolerated, but some individuals may exhibit sensitivity, particularly if they have allergies to related mushroom species. Allergic reactions can include digestive issues, skin rashes, and, in rare instances, anaphylaxis.
Honey Mushrooms (Armillaria mellea): Honey mushrooms are widely distributed and known for their distinctive honey-colored caps. While they are edible and provide nutritional benefits, they can also cause adverse reactions. Honey mushrooms contain a unique compound called armillarin, which has potential anti-cancer properties but may also be toxic in large doses. Additionally, individuals allergic to other types of fungi may be sensitive to honey mushrooms, experiencing symptoms such as nausea, vomiting, and diarrhea.
In conclusion, while mushrooms offer nutritional and potential health benefits, it is important to approach them with caution. Always properly identify wild mushrooms before consumption, as some species can be toxic or deadly. Additionally, if you have known allergies or respiratory conditions, exercise caution when introducing new mushroom varieties into your diet, and consult a healthcare professional if you experience any adverse symptoms.
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The prevalence of mushroom allergies
Mushrooms are widely consumed as a nutritious food worldwide, but they can cause allergic reactions in some individuals. Mushroom allergies are triggered when the body's immune system mistakenly identifies the proteins in mushrooms as harmful. This response results in an increase in histamine levels, leading to symptoms such as gastrointestinal issues, inflammation, and swelling. Those allergic to mould are more likely to also be allergic to mushrooms.
There are numerous species of mushrooms, and the specific allergens within each species are not yet fully understood. The majority of allergenic mushrooms and fungi grow in both Europe and North America, with certain species unique to specific regions. For example, the genus Chlorophyllum is only found in North America, while its close relative, Macrolepiota, is common in Europe.
The extent of mushroom allergies also varies locally and annually, depending on species and spore concentrations in different environments. Mushroom allergies can be induced through inhalation, ingestion, or skin contact, with respiratory allergies attributed to spores and ingestion allergies to other parts of the mushroom.
Fungus-related foods, including edible mushrooms, mycoprotein, and fermented foods, can cause fungus food allergy syndrome (FFAS) through allergic cross-reactivity with airborne fungi. FFAS can manifest in various organs, ranging from oral allergy syndrome to severe anaphylaxis. While adverse reactions to mycoprotein are rare, they have been reported and can include urticaria, throat swelling, and breathing difficulties.
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Frequently asked questions
Yes, some people are allergic to mushrooms. Mushroom allergy is an immune system response to the proteins in mushrooms. The symptoms can range from mild to severe and can be life-threatening in some cases.
The symptoms of a mushroom allergy can include anaphylaxis, a severe allergic reaction that can cause a drop in blood pressure, difficulty breathing, and loss of consciousness. Other symptoms may include gastrointestinal issues, itching, hives, and rashes.
The most effective treatment for a mushroom allergy is to avoid consuming mushrooms altogether. Mild allergic reactions can be treated with home remedies like antihistamines, vitamin C, and aloe vera. In severe cases, an injection of epinephrine (also known as adrenaline) may be required to reverse the symptoms of anaphylaxis.

























