
Magic mushrooms, or psychedelic mushrooms, are known for their hallucinogenic effects. However, recent years have seen a resurgence of interest in their potential health benefits. Research suggests that controlled psilocybin therapy may show promise in treating mental and behavioural health disorders, including depression, anxiety, PTSD, OCD, addiction, and anorexia nervosa. Microdosing, or taking tiny amounts of psilocybin mushrooms, has become a popular trend, with many people believing it can enhance their mood, creativity, concentration, productivity, and empathy. While some studies have found evidence to support these claims, others have been less conclusive, and more research is needed to determine the safety and efficacy of microdosing.
| Characteristics | Values |
|---|---|
| Potential health benefits | Easing depression, anxiety, PTSD, OCD, addiction, cluster headaches, anorexia nervosa, and smoking cessation |
| Therapeutic benefits | Treating depression and anxiety due to end-stage cancer |
| Microdosing benefits | Enhancing mood, creativity, concentration, productivity, and ability to empathize with others |
| Safety | Poisoning is possible if the wrong type of mushroom is consumed; a large dose can lead to a terrifying or traumatic experience |
| Legality | Psilocybin is a Schedule I substance, meaning it is considered to have a high potential for abuse and no legitimate medical purpose |
| Research | Research is ongoing, with mixed results; some studies have shown positive effects, while others have been less impressive |
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What You'll Learn

Microdosing may enhance mood, creativity, concentration, and productivity
Microdosing, or taking tiny amounts of psychedelic mushrooms, has gained popularity as a way to enhance mood, creativity, concentration, and productivity. This practice involves consuming a fraction of a regular dose of psilocybin mushrooms, typically around 0.1 to 0.3 grams of dried mushrooms. While there is some scientific evidence to support these benefits, the effects of microdosing are still being studied and understood.
Several studies have found positive effects of microdosing on mood and mental health. One study compared 953 psilocybin microdosers to 180 non-dosing participants over 30 days and found small to medium-sized improvements in mood and mental health across different demographics. Another study conducted by researchers at Johns Hopkins found that adults who took a single 25-milligram dose of psilocybin with psychological support experienced a significant reduction in depressive symptoms compared to adults who took a placebo. These findings suggest that psilocybin may have therapeutic potential for treating depression and improving mood.
In addition to mood enhancement, microdosing may also improve creativity and concentration. Some people who microdose report feeling happier and more creative, with increased ability to focus. The practice of microdosing is believed by some to maintain brain health and promote a creative perspective on life. The improved openness found in people who take psilocybin may be due to the chemical's ability to increase neuroplasticity, allowing the brain to create new connections and break out of negative thought patterns.
Microdosing may also enhance productivity and overall mental health. Some individuals take microdoses of psilocybin with the intention of improving mental health symptoms such as depression and stress, as well as increasing productivity. While there is anecdotal evidence to support these benefits, more research is needed to determine the safety and effectiveness of microdosing. The potency of mushrooms can vary, and they are not regulated outside of clinical trials, making it challenging to perform consistent research.
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Can be used to treat mental health disorders
Psychedelic mushrooms have been found to be effective in treating various mental health disorders. In recent years, there has been a resurgence of research interest in the potential therapeutic benefits of psychedelic drugs, including psilocybin, the active compound in magic mushrooms.
Depression and Anxiety
Small-scale studies have shown that one or two doses of psilocybin, administered in a therapeutic setting, can lead to dramatic and long-lasting improvements in people with treatment-resistant major depressive disorder. A 2022 study found that participants who received two doses of psilocybin over a period of several months experienced reduced depression levels for up to one year after treatment. Additionally, a 2023 clinical trial demonstrated that a single dose of psilocybin, combined with psychological support, resulted in a significant reduction in depressive symptoms compared to a placebo group. Psilocybin's ability to enhance neuroplasticity and increase the brain's adaptability may contribute to its antidepressant effects, helping individuals break free from negative thought patterns associated with depression and anxiety.
Post-Traumatic Stress Disorder (PTSD)
Psilocybin has been explored as a potential treatment for PTSD. While more research is needed, initial findings suggest that psychedelic-assisted psychotherapy may help alleviate existential distress and psychological distress associated with traumatic experiences.
Addiction
Research has also examined the potential of psilocybin in treating addiction. For example, the National Institute of Health awarded a grant to explore psilocybin's efficacy in smoking cessation, recognizing its potential as a treatment for addictive behaviours.
Other Disorders
Psychedelic mushrooms have shown promise in treating additional mental health disorders. For instance, psilocybin therapy has yielded encouraging preliminary results in the treatment of anorexia nervosa. Furthermore, psilocybin's ability to induce a state of heightened neuroplasticity may have implications for managing obsessive-compulsive disorder (OCD) and other conditions characterized by rigid thought patterns.
While the potential benefits of psychedelic mushrooms in treating mental health disorders are intriguing, it is important to approach their use with caution. The effects of psilocybin are highly variable and depend on factors such as mental health status, setting, quantity consumed, and individual expectations. Additionally, consuming mushrooms containing psilocybin carries risks, including the possibility of adverse reactions such as anxiety, paranoia, and disturbing hallucinations. Therefore, it is crucial to have a trusted source for the mushrooms and to seek guidance from mental health professionals when considering their therapeutic use.
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May help treat addiction
While psilocybin mushrooms are currently classified as a Schedule I substance by the Drug Enforcement Administration (DEA), which means they are believed to have a high potential for abuse and no legitimate medical purpose, there is a growing body of research that suggests they may have therapeutic benefits in treating addiction.
One of the most notable studies on the potential benefits of psilocybin mushrooms for addiction treatment was conducted by Griffiths and his team at Johns Hopkins University. They found that psilocybin can induce mystic-type experiences, which are a major factor in why a single exposure to the substance often produces substantial and enduring anti-addictive effects. In fact, 80% of the participants in the Griffiths study rated their experience with psilocybin as one of the top five most meaningful experiences of their lives.
Psilocybin-assisted therapy has also been found to be effective in treating addiction to substances such as cigarettes, with an 80% abstinence rate six months after treatment, compared to the general six-month smoking cessation rates of 15-30% obtained by current treatment modalities. Additionally, research from Harvard Medical School and Boston University reported that psychedelic substances had a protective effect on opioid addiction. Furthermore, psilocybin has been found to be effective in treating alcohol use disorder, with two doses of psilocybin pills, along with psychotherapy, helping people reduce drinking for at least eight months after their first treatments.
While the exact mechanism of how psilocybin-assisted therapy works is still being studied, it is believed that it may reshape the neural networks in the brain that are associated with addiction-related habits and help individuals escape rigid thinking patterns. Additionally, functional magnetic resonance imaging (fMRI) studies have shown that the states of consciousness induced by psilocybin are nearly identical to those achieved by accomplished meditators, suggesting that psilocybin may stimulate the brain growth necessary for learning and change.
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May ease depression and anxiety
While psychedelic mushrooms are currently designated as a Schedule 1 drug by US federal law due to their hallucinogenic properties and potential for abuse, research suggests that they may offer certain health benefits. One notable area of exploration is the potential of psilocybin, the psychedelic compound found in magic mushrooms, to ease symptoms of depression and anxiety.
Small clinical trials have shown that one or two therapeutic doses of psilocybin can bring about dramatic and long-lasting improvements in people with treatment-resistant major depressive disorder, a condition that typically does not respond to traditional antidepressants. A 2023 study found that adults who took a single 25mg dose of psilocybin alongside psychological support experienced a significant reduction in depressive symptoms compared to adults who took a placebo. Furthermore, a follow-up study by Johns Hopkins Medicine researchers found that the antidepressant effects of psilocybin-assisted therapy may last at least a year for some patients, with remission of symptoms observed even after 12 months.
The potential efficacy of psilocybin in treating depression may be attributed to its ability to regulate the brain's reward system and act on specific serotonin receptors, resulting in alterations to mood, cognition, and perception. These changes in consciousness may facilitate therapeutic growth and enable individuals to manage their symptoms more effectively. Additionally, psilocybin has been found to produce effects similar to those of LSD, including altered perception of time and space, intense changes in mood and feeling, and sensory distortion.
While the research on the benefits of psychedelic mushrooms is promising, it is important to approach their consumption with caution. Factors such as mental health history, setting, quantity, and expectations can influence the experience and impact of taking psilocybin. Furthermore, taking too large a dose may result in a traumatic experience, and it is crucial to obtain mushrooms from a trusted source to avoid poisoning, as some mushrooms that resemble psychedelic varieties can be poisonous and harmful to the liver.
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May have negative side effects
While psychedelic mushrooms may offer some health benefits, they may also have negative side effects.
Firstly, it is very easy to poison oneself with the wrong type of mushroom. There are many types of mushrooms in nature that look similar to each other, but some are poisonous and can harm the liver, causing severe illness or even death.
Secondly, even when consuming the right type of mushroom, taking too large a dose can result in a terrifying or even traumatic experience. A 2020 analysis suggests that higher doses of psilocybin may increase the risk of negative experiences.
Thirdly, although current research suggests that psilocybin is not addictive, users may experience disturbing hallucinations, anxiety, paranoia, panic, or short-term psychosis. A pre-existing mental health condition may also increase the risk of negative experiences.
Finally, the potency of mushrooms can vary greatly as they are not regulated outside of clinical trials, making it difficult to determine the appropriate dosage and potentially increasing the risk of adverse effects.
While psychedelic mushrooms may show promise in treating certain conditions, it is important to approach their consumption with caution due to the potential negative side effects.
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Frequently asked questions
Psychedelic mushrooms, also known as magic mushrooms, are fungi that contain the hallucinogenic chemical psilocybin.
Some studies have shown that psychedelic mushrooms may have therapeutic benefits for people with depression, anxiety, PTSD, OCD, addiction, and cluster headaches. One study found that participants' depression levels remained low for up to 12 months after treatment with psilocybin. Another study found that psilocybin may help treat depression and anxiety due to end-stage cancer.
Psilocybin increases neuroplasticity in the brain, allowing it to create new connections, become more adaptive, and break out of negative thought patterns.
Microdosing is the practice of taking small amounts of psychedelic mushrooms several times a week to maintain brain health and enhance mood, creativity, concentration, and productivity. A typical microdose is around 0.1 to 0.3 grams of dried psilocybin mushrooms.
While psilocybin is not considered addictive, taking too large of a dose can lead to negative experiences such as disturbing hallucinations, anxiety, paranoia, and short-term psychosis. It is also very easy to poison oneself with the wrong type of mushroom, as many types of mushrooms in nature look similar but are poisonous and can cause severe illness or even death.

























