Michael Davis
Microdosing with psilocybin mushrooms has gained popularity in recent years, with many believing that it can enhance mood, creativity, concentration, productivity, and empathy. However, research on the effects of microdosing is limited, and the evidence from recent studies is mixed. When it comes to dosing psilocybin mushrooms, it's important to start with a low dose and gradually increase, as the effects can vary depending on individual factors such as body weight and suggestibility. The average psilocybin content is about 1% per gram of dried Psilocybe cubensis mushroom, so a 25 mg psilocybin fixed dose is approximately 2.5 grams of dried mushrooms. It's crucial to obtain mushrooms from a trusted source, as some varieties are poisonous and can cause severe illness or even death.
| Characteristics | Values |
|---|---|
| Microdose | 0.5 g of dried mushrooms |
| Fixed dose | 25 mg psilocybin |
| Average psilocybin content | 1% psilocybin per one gram of dried Psilocybe cubensis mushroom |
| Medium dose | 2.0 to 3.0 grams |
| Heroic dose | Over 5 grams of dried mushrooms |
| Weight-adjusted dose | 20 to 30 mg/70 kg |
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What You'll Learn
Microdosing: small, non-perceptual amounts
Microdosing involves taking a small amount of a hallucinogenic substance to seek a positive effect on the mind without a psychedelic experience. Microdosing is a method of studying and understanding the effects of pharmacologically active substances.
The commonly accepted phrase "microdosing" when it comes to psychedelics is a misnomer; the actual amounts consumed are more analogous to a "low dose" or "very low dose" of the psychedelic itself. Microdoses are typically defined as 5-10% of a standard psychoactive dose, which for psilocybin is generally estimated to be between 0.1 and 0.3 grams (100 to 300 mg) of dried Psilocybe cubensis mushrooms. However, the appropriate dosage can range widely based on the potency of the strain and individual factors. Generally, a microdose is considered to be between 50 mg (0.05 g) and 800 mg (0.8 g) of dried mushroom.
It is important to start with the lowest dose to gauge individual sensitivity, as factors such as personal biology and tolerance can significantly influence the effects. Microdoses will typically last four to six hours and are best taken at a time of day when one can allow for a level of emotions and creativity to come to the surface.
A significant trend in the microdosing community is the practice of "stacking", which involves combining a psilocybin microdose with other non-psychoactive supplements to create a synergistic effect.
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Medium dose: 2-3 grams
A medium dose of psychedelic mushrooms usually contains between two and three grams. This dose will induce noticeable changes in your perception and thought patterns. Generally speaking, consuming two to 3.5 grams of mushrooms means that you are taking a standard dose.
Ingesting this amount of psilocybin mushrooms generally brings on hallucinations and a suite of psychedelic effects, such as colourful visual imagery and an altered perception of time. It's important to note that a gram of dried mushrooms is about the same size as a paperclip. A fresh gram (undried) would look larger because fresh mushrooms are mostly water.
The price of a gram of shrooms varies depending on the location, type, and quality. On average, a gram of shrooms costs between $7 and $15. However, small purchases of 1-3 grams can cost users $10-$30 per gram. The price may also depend on the species of mushroom, the vendor, and the location.
When it comes to dosing out mushrooms, it's important to start with a low dose and increase gradually. This is especially important if you are using dried mushrooms, as the psilocybin content can vary from batch to batch. It's also worth noting that the same dose of mushrooms can affect different people in different ways. Individual experiences can be influenced by factors such as the species of mushroom, body composition, chemistry, emotional state, and environment.
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Fixed dose: 25 mg
A fixed dose of 25 mg of psilocybin has been validated in recent studies, which found no significant differences in psychedelic effects when compared to weight-based doses of 0.29 mg/kg and 0.43 mg/kg. This suggests that a fixed dose approach can be effective for patients, providing convenience and lower costs when compared to weight-adjusted dosing.
The 25 mg fixed dose of psilocybin is typically administered in the form of dried Psilocybe cubensis mushrooms, which are commonly known as "magic mushrooms." On average, dried Psilocybe cubensis mushrooms contain approximately 1% psilocybin per gram, so a 25 mg psilocybin dose would equate to around 2.5 grams of dried mushrooms. However, it is important to note that there can be variability in psilocybin content between different batches and species of mushrooms, so it is always good practice to start with a lower dose when using a new batch or species.
When taking a fixed dose of 25 mg psilocybin, it is essential to source the mushrooms from a trusted provider to ensure safety. Psilocybin is generally considered safe in low doses and has been used for centuries by indigenous peoples. However, taking too large of a dose can result in a traumatic experience, and it is very easy to accidentally consume poisonous mushrooms, which can cause severe illness or even death.
Additionally, it is worth noting that the effects of psilocybin can vary from person to person, and individual sensitivity to psilocybin may play a role in the variability of effects. Some people may experience subtle effects such as improved mood or energy at a 25 mg dose, while others may require a higher dose to achieve the desired therapeutic benefits. It is always recommended to start with a lower dose and gradually increase as needed to find the ideal dose for your specific needs and goals.
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Weight-adjusted dose: 20-30 mg/70 kg
Psilocybin, a naturally occurring psychedelic found in certain types of mushrooms, has gained popularity for its therapeutic effects. When it comes to dosing out mushrooms, there are a few approaches that can be considered, such as microdosing and weight-adjusted dosing.
Weight-adjusted dosing for psilocybin falls typically within the range of 20-30 mg/70 kg. This range has been identified as safe and likely to yield therapeutic outcomes in clinical populations, as well as positive persisting effects in healthy individuals. The specific dose within this range may depend on various factors and should be carefully considered and monitored.
For instance, in studies examining the effects of psilocybin on mood and substance use disorders, participants received doses of either 20 mg/70 kg or 30 mg/70 kg. These doses were chosen to evaluate the effects of different weights on acute subjective effects such as mystical effects, challenging effects, and intensity. The results of these studies showed no significant associations between subjective effects and demographic variables, including body weight or sex.
It is important to note that the effects of psilocybin can vary between individuals, and there may be intra- and inter-species variability in psilocybin content. Therefore, when using dried mushrooms, it is recommended to start with a lower weight, especially for individuals who are new to psilocybin. Additionally, the underlying causes for varying sensitivities to psilocybin effects are not yet fully understood, and further research is needed to optimize dosing protocols.
In conclusion, when considering weight-adjusted dosing for mushrooms, the range of 20-30 mg/70 kg has been studied and deemed safe, with potential therapeutic benefits. However, it is important to approach dosing with caution, considering individual factors and sensitivities, and to seek guidance from healthcare professionals familiar with psilocybin therapy.
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Heroic dose: over 5 grams
A 'heroic dose', as defined by Terrence McKenna, is a dose of over 5 grams of dried mushrooms, or roughly 50 mg of psilocybin. This massive dose may cause a complete loss of the sense of self, or "ego dissolution" and "ego death," as well as a loss of the ability to think or make decisions. This level of cognitive impairment should not be taken lightly, and careful preparation and supervision are necessary to ensure safety.
It is important to note that the effects of a heroic dose of mushrooms may be significantly more intense than those of a lower dose. While some people may experience positive effects such as enhanced mood, creativity, and problem-solving abilities, others may have negative experiences. The underlying causes for varying sensitivities to psilocybin effects are not fully understood, but research suggests that they may be due to differences in 5-HT2A receptors in the brain.
Before consuming a heroic dose of mushrooms, it is crucial to follow the golden rule of "start low, go slow." This means that individuals should start with a lower dose and gradually increase it over time to get used to the effects and reduce the risk of negative experiences. Additionally, it is essential to ensure that the mushrooms are obtained from a trusted source and that the species are correctly identified, as some mushrooms can be poisonous and harmful to the liver or even fatal.
When preparing for a heroic dose experience, it is recommended to do it on familiar ground and with people you are comfortable with. It may also be beneficial to have a practice run on your own to get a sense of the effects before partaking in social situations. During the experience, individuals may feel a sense of unity, sacredness, and a deeply positive mood. However, it is important to remember that every individual is unique, and each psychedelic experience is different, depending on various factors such as suggestibility and absorption.
Overall, while a heroic dose of mushrooms can be a profound and transformative experience, it should be approached with caution and respect. It is not a decision to be taken lightly, and proper preparation and a supportive environment are crucial for a safe and positive journey.
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Frequently asked questions
Microdosing involves consuming small, non-perceptual amounts of psilocybin-containing mushrooms. This means that you don’t feel or perceive any of the mind-altering effects of the mushroom, but you may feel subtle effects like a boost in mood or energy.
If you have limited or no experience with psilocybin, it is wise to follow the golden rule of “start low, go slow”. Microdosing protocols typically contain 100 mg to 250 mg of dried magic mushrooms (5-10% of a standard dose) consumed across dosing days and days off.
A medium dose of psilocybin mushrooms is considered to be between 2.0 and 3.0 grams. At this dose, you will likely feel psychedelic effects but may still be able to walk around and maintain a sense of self. A "heroic dose" is considered to be over 5 grams of dried mushrooms.
