
Microdosing is the practice of taking small amounts of psychedelic substances such as psilocybin mushrooms and LSD. The goal is to experience the potential benefits of psychedelics without impairing cognitive functioning or causing hallucinations. While some proponents of microdosing claim it offers a range of mental and physical health benefits, including enhanced creativity, reduced depression symptoms, and improved focus, the evidence from recent studies is mixed. The ambiguity of the science and the illegality of these substances in many places have not stopped people from experimenting with microdosing, with some reporting positive effects on their mood, mindset, and productivity.
| Characteristics | Values |
|---|---|
| Definition | Taking a fraction of a regular dose of psychedelics |
| Drugs | Psilocybin, LSD, caffeine, nicotine |
| Dosage | 0.1-0.3mg of psilocybin, 5-20mcg of LSD |
| Frequency | 3-5 times per week |
| Benefits | Enhanced mood, creativity, focus, energy, well-being, mental health, and performance |
| Side effects | Jitteriness, headaches, anxiety, neuroticism, dependence, abuse |
| Legality | Illegal in the US, potential legal consequences |
| Research | Mixed results, limited evidence, small sample sizes |
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What You'll Learn
- Microdosing may improve mood, focus, and mental health
- It may reduce symptoms of depression, stress, and anxiety
- There is limited research on its effectiveness, with mixed results
- Microdosing is generally regarded as low risk, but it may have side effects
- It is illegal in many places, and dosages may be inconsistent

Microdosing may improve mood, focus, and mental health
Microdosing involves the regular self-administration of psychedelic substances in doses small enough to not impair normal cognitive functioning. The most widely reported substances used for microdosing are psilocybin mushrooms and LSD, and to a lesser degree, other psychedelic substances such as mescaline and 2-CB.
Microdosing is said to offer a range of mental and physical health benefits, but the evidence is mixed. Some people claim that microdosing helps boost energy levels and enhance focus, and that it helps with certain medical concerns. A 2019 study found that participants reported some benefits, including decreased depression symptoms and increased focus. However, these effects were short-lived, disappearing after a day or two.
Proponents of microdosing claim that the practice offers a host of benefits, from enhanced creativity to reduced depression symptoms. However, current research suggests there is not much to support the hype. Microdosing is more complicated than it sounds, and most substances used in microdosing are illegal in many areas. This also means that there is a lack of high-quality scientific evidence on the topic.
A study published in Scientific Reports found that psilocybin microdosers demonstrated greater observed improvements in mood and mental health at one month relative to non-microdosing controls. The study followed psilocybin microdosers (n = 953) and non-microdosing comparators (n = 180) for approximately 30 days and identified small- to medium-sized improvements in mood and mental health that were generally consistent across gender, age, and presence of mental health concerns.
It is important to note that the effects of microdosing may be due to a large placebo effect, and that there is not yet enough scientific evidence to say whether microdosing is safe. The ambiguity of the science and the remaining taboo around psychedelics have not stopped people from trying it themselves, with some comparing the feeling to a strong cup of coffee or a state of flow.
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It may reduce symptoms of depression, stress, and anxiety
Microdosing involves the regular self-administration of psychedelic substances in doses small enough to not impair normal cognitive functioning. The most widely reported substances used for microdosing are psilocybin mushrooms and LSD, and to a lesser degree, other psychedelic substances such as mescaline and 2-CB.
Microdosing is said to offer a range of mental and physical health benefits, but the evidence from some recent studies is mixed. Some studies have shown that microdosing may reduce symptoms of depression, stress, and anxiety. For example, a 2021 study by Wang et al. found that psilocybin microdosers demonstrated greater improvements in mood and mental health at one month relative to non-microdosing controls. The study followed 953 psilocybin microdosers and 180 non-microdosers for approximately 30 days, identifying small- to medium-sized improvements in mood and mental health that were consistent across gender, age, and presence of mental health concerns.
Another study by Adam Golner and Patrick K. Kroupa in 2022 found that psilocybin microdosers reported improvements in mood, emotional well-being, and cognition, as well as reductions in stress, depression, and anxiety. The study surveyed microdosing practices and generally found the self-administration of 0.1 to 0.3 grams of dried mushrooms 3–5 times per week. These improvements were also reported by mothers in Colorado who began a regimen of microdosing psychedelics to ease the stress and anxiety associated with being a mother on the go.
However, it is important to note that the evidence for the benefits of microdosing is not conclusive. Some studies have found little to no benefit, and there is a lack of consistent research due to the varying definitions of microdosing and the illegal status of psychedelic substances in many areas. Additionally, the improvements reported in the studies mentioned above were based on self-reported data, which can be difficult to validate. Furthermore, there may be a large placebo effect with microdosing, where people who expect an effect from microdosing seem to notice the most benefit. More clinical trials and research are needed to fully understand the potential benefits of microdosing.
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There is limited research on its effectiveness, with mixed results
Microdosing involves taking a fraction of a regular dose of psychedelic substances. Many people believe that microdosing can enhance their mood, creativity, concentration, productivity, and ability to empathize with others. However, there is limited research on its effectiveness, with mixed results.
A 2024 review looked at existing controlled trials involving LSD, comparing the effects of a microdose of LSD to those of a placebo. The review found that microdosing showed little to no benefit for increasing creativity or productivity. Some participants experienced jitteriness, headaches, or anxiety, but no serious side effects were reported.
Another study conducted a randomized controlled trial with 34 participants, half of whom received psilocybin and half of whom received a placebo. While some intriguing subjective effects were observed, such as participants feeling happier and more creative, and changes in brain waves were recorded on an EEG machine, the researchers concluded that low-dose psilocybin mushrooms did not show objective evidence of improvements in creativity, well-being, and cognitive function.
The lack of consistent research in this area is partly due to the fact that there isn't a single, clearly recognized definition of microdosing for any psychedelic drug. The potency of mushrooms can also vary greatly, as they are not regulated outside of clinical trials. Additionally, most substances used in microdosing are illegal in many areas, further limiting the availability of high-quality scientific evidence.
While some studies have found limited or mixed results, other research suggests that microdosing psilocybin mushrooms may lead to improvements in mood and mental health. One study followed psilocybin microdosers (n = 953) and non-microdosing comparators (n = 180) for approximately 30 days and identified small- to medium-sized improvements in mood and mental health that were consistent across gender, age, and the presence of mental health concerns. However, more research is needed to confirm these findings and to understand the potential risks and benefits of microdosing.
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Microdosing is generally regarded as low risk, but it may have side effects
Microdosing typically involves taking small doses of psychedelic substances, including LSD and psilocybin ("magic mushrooms"). It is important to note that the substances used in microdosing are typically illegal in many areas, and there are potential legal consequences associated with their use.
While microdosing is generally regarded as low risk, it is essential to understand that it may still have side effects. The evidence regarding the benefits of microdosing is mixed, with some studies suggesting little to no improvement in creativity, productivity, or cognitive function. Additionally, the lack of standardised dosing in many studies makes it difficult to draw definitive conclusions.
Some people who have tried microdosing mushrooms have reported positive effects, claiming that it helps boost their mood, focus, and creativity, as well as reduce symptoms of depression and anxiety. However, it's important to note that these reports are often anecdotal and may be influenced by the "'expectancy effect,' where the belief in the substance's effectiveness influences the perceived outcome.
It is worth noting that the potential benefits of microdosing may be short-lived, lasting only a day or two. Additionally, some participants in studies have reported negative side effects, including jitteriness, headaches, increased neuroticism, and heightened intensity of emotions, both positive and negative. Furthermore, due to the lack of regulation of substances outside of clinical trials, it can be challenging to ensure the correct dosage and avoid taking higher doses than intended, which may lead to negative side effects.
While microdosing mushrooms may be regarded as relatively low risk, it is important to approach it with caution. The potential side effects, the possibility of incorrect dosing, and the legal status of the substances in many areas are all important considerations. More research is needed to fully understand the benefits and risks associated with microdosing mushrooms.
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It is illegal in many places, and dosages may be inconsistent
Microdosing involves taking small doses of psychedelic substances, such as psilocybin ("magic mushrooms"), several times a week. While some people claim that microdosing enhances their mood, creativity, concentration, and productivity, the evidence from recent studies is mixed. Furthermore, the substances used in microdosing are illegal in many places, and the dosages may be inconsistent, which can lead to negative side effects.
The legality of microdosing mushrooms varies depending on the region. In the United States, for example, psychedelics are still illegal, and people who use them may face legal repercussions. This illegality has hindered scientific research on the topic, as researchers may face legal challenges when conducting studies involving controlled substances. As a result, much of the existing research on microdosing relies on self-reported data, which can be difficult to validate.
The ambiguity of the science and the remaining taboo around psychedelics have not stopped people from experimenting with microdosing. However, it is important to note that the substances used in microdosing are often obtained from unregulated sources, and the potency and dosage of these substances can vary greatly. This inconsistency in dosage can lead to negative side effects, as it is difficult to determine the proper dose for each individual.
Psilocybin mushrooms, for example, can come in various strengths and forms, such as mushroom-infused honey or mushroom powder in capsules. A typical hallucinogenic dose of psilocybin is around 20 mg, while a microdose is generally considered to be between 1 mg and 2 mg. However, the potency of mushrooms can vary, and without proper regulation, it is challenging to ensure consistent dosages.
Additionally, physiological tolerance to the substances used in microdosing can develop over time, leading to diminishing returns and the need for higher doses to achieve the desired effect. This can further complicate the issue of inconsistent dosages, as individuals may unintentionally increase their dosage in an attempt to achieve the same effects as when they started microdosing. Therefore, while microdosing may offer potential benefits, it is important to approach it with caution due to the varying legal status, inconsistent dosages, and potential for negative side effects.
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Frequently asked questions
Microdosing is the act of taking a small amount of a psychedelic drug, such as psilocybin ("magic mushrooms"), several times a week. The amount is usually low enough to not cause hallucinations.
Some people who microdose mushrooms report benefits such as improved mood, enhanced focus, reduced depression and anxiety, and increased energy levels. However, it is important to note that the evidence for these benefits is mixed, with some studies showing little to no improvement in creativity, productivity, or cognitive function.
Microdosing mushrooms is generally considered to have a low risk of negative side effects when obtained from a trusted source. However, there is a potential for legal consequences depending on the region, as well as the possibility of contaminants or incorrect dosage when obtained from unregulated sources. Some reported side effects include jitteriness, headaches, and increased neuroticism or unwanted emotions.
A typical microdose of psilocybin mushrooms is around 0.1 to 0.3 grams of dried mushrooms, taken 3-5 times per week. However, it is important to note that the potency of mushrooms can vary, and there is no standard dosage that is universally agreed upon.
Microdosing psilocybin can be done through various methods, including consuming dried, powdered mushrooms, mushroom-infused honey, or mushroom capsules. Some people also combine psilocybin with other substances like lion's mane mushrooms and niacin (vitamin B3).

























